Details for: Nell2

Gene ID: 54003

Symbol: Nell2

Ensembl ID: ENSMUSG00000022454

Description: NEL-like 2

Associated with

Other Information

Genular Protein ID: 1206562467

Symbol: NELL2_MOUSE

Name: Protein kinase C-binding protein NELL2

UniProtKB Accession Codes:

Q61220 Q80UM5

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CCDS 1 CDD 2 CTD 1 ChEBI 18 ChiTaRS 1 EMBL 5 Ensembl 2 ExpressionAtlas 1 GO 15 Gene3D 4 GeneTree 1 Genevisible 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 10 KEGG 1 MGI 2 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRO 1 PROSITE 7 PROSITE-ProRule 2 PaxDb 1 PeptideAtlas 1 Pfam 4 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 RefSeq 3 SMART 6 SMR 1 STRING 1 SUPFAM 3 SwissPalm 1 TreeFam 1 UCSC 1 UniProtKB 2 VEuPathDB 1 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 26586761

Title: Operational redundancy in axon guidance through the multifunctional receptor Robo3 and its ligand NELL2.

PubMed ID: 26586761

DOI: 10.1126/science.aad2615

PubMed ID: 32499443

Title: NELL2-mediated lumicrine signaling through OVCH2 is required for male fertility.

PubMed ID: 32499443

DOI: 10.1126/science.aay5134

PubMed ID: 32198364

Title: NELL2-Robo3 complex structure reveals mechanisms of receptor activation for axon guidance.

PubMed ID: 32198364

DOI: 10.1038/s41467-020-15211-1

PubMed ID: 37095084

Title: A small secreted protein NICOL regulates lumicrine-mediated sperm maturation and male fertility.

PubMed ID: 37095084

DOI: 10.1038/s41467-023-37984-x

Sequence Information:

  • Length: 819
  • Mass: 91432
  • Checksum: 530ECD363029571D
  • Sequence:
    • MHAMESRVLL RTFCVILGLG AVWGLGVDPS LQIDVLTELE LGESTDGVRQ VPGLHNGTKA 
FLFQESPRSI KASTATAERF FQKLRNKHEF TILVTLKQIH LNSGVILSIH HLDHRYLELE 
SSGHRNEIRL HYRSGTHRPH TEVFPYILAD AKWHKLSLAF SASHLILHID CNKIYERVVE 
MPSTDLPLGT TFWLGQRNNA HGYFKGIMQD VHVLVMPQGF IAQCPDLNRT CPTCNDFHGL 
VQKIMELQDI LSKTSAKLSR AEQRMNRLDQ CYCERTCTVK GTTYRESESW TDGCKNCTCL 
NGTIQCETLV CPAPDCPPKS APAYVDGKCC KECKSTCQFQ GRSYFEGERN TVYSSSGMCV 
LYECKDQTMK LVENIGCPPL DCPESHQIAL SHSCCKVCKG YDFCSEKHTC MENSVCRNLN 
DRAVCSCRDG FRALREDNAY CEDIDECAEG RHYCRENTMC VNTPGSFMCI CKTGYIRIDD 
YSCTEHDECL TNQHNCDENA LCFNTVGGHN CVCKPGYTGN GTTCKAFCKD GCRNGGACIA 
ANVCACPQGF TGPSCETDID ECSEGFVQCD SRANCINLPG WYHCECRDGY HDNGMFAPGG 
ESCEDIDECG TGRHSCTNDT ICFNLDGGYD CRCPHGKNCT GDCVHEGKVK HTGQIWVLEN 
DRCSVCSCQT GFVMCRRMVC DCENPTVDLS CCPECDPRLS SQCLHQNGET VYNSGDTWVQ 
DCRQCRCLQG EVDCWPLACP EVECEFSVLP ENECCPRCVT DPCQADTIRN DITKTCLDEM 
NVVRFTGSSW IKHGTECTLC QCKNGHLCCS VDPQCLQEL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.