Details for: Deaf1

Gene ID: 54006

Symbol: Deaf1

Ensembl ID: ENSMUSG00000058886

Description: DEAF1, transcription factor

Associated with

  • Behavioral fear response
    (GO:0001662)
  • Cytoplasm
    (GO:0005737)
  • Dna-binding transcription factor activity, rna polymerase ii-specific
    (GO:0000981)
  • Dna-binding transcription repressor activity, rna polymerase ii-specific
    (GO:0001227)
  • Dna binding
    (GO:0003677)
  • Embryonic skeletal system development
    (GO:0048706)
  • Fibrillar center
    (GO:0001650)
  • Metal ion binding
    (GO:0046872)
  • Multicellular organism development
    (GO:0007275)
  • Negative regulation of dna-templated transcription
    (GO:0045892)
  • Negative regulation of transcription by rna polymerase ii
    (GO:0000122)
  • Nervous system development
    (GO:0007399)
  • Neural tube closure
    (GO:0001843)
  • Nucleoplasm
    (GO:0005654)
  • Nucleus
    (GO:0005634)
  • Positive regulation of dna-templated transcription
    (GO:0045893)
  • Positive regulation of transcription by rna polymerase ii
    (GO:0045944)
  • Protein binding
    (GO:0005515)
  • Regulation of mammary gland epithelial cell proliferation
    (GO:0033599)
  • Regulation of transcription by rna polymerase ii
    (GO:0006357)
  • Rna polymerase ii transcription regulator complex
    (GO:0090575)
  • Rna polymerase ii transcription regulatory region sequence-specific dna binding
    (GO:0000977)
  • Visual learning
    (GO:0008542)

Other Information

Genular Protein ID: 3888193363

Symbol: DEAF1_MOUSE

Name: Deformed epidermal autoregulatory factor 1 homolog

UniProtKB Accession Codes:

Q9Z1T5 C7SHZ9 Q3UJA4

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CCDS 1 CTD 1 ChEBI 8 ChiTaRS 1 DNASU 1 EMBL 5 Ensembl 1 ExpressionAtlas 1 GO 19 Gene3D 2 GeneTree 1 Genevisible 1 GlyGen 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MGI 1 MINT 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PDB 1 PDBsum 1 PRO 1 PROSITE 3 PROSITE-ProRule 2 PaxDb 1 Pfam 2 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 RNAct 1 RefSeq 1 SAM 1 SMART 1 SMR 1 STRING 1 SUPFAM 2 TreeFam 1 UCSC 1 UniProtKB 2 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1

Citations:

PubMed ID: 9860983

Title: Mouse deformed epidermal autoregulatory factor 1 recruits a LIM domain factor, LMO-4, and CLIM coregulators.

PubMed ID: 9860983

DOI: 10.1073/pnas.95.26.15418

PubMed ID: 19668219

Title: Deaf1 isoforms control the expression of genes encoding peripheral tissue antigens in the pancreatic lymph nodes during type 1 diabetes.

PubMed ID: 19668219

DOI: 10.1038/ni.1773

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 14966286

Title: Defective neural tube closure and anteroposterior patterning in mice lacking the LIM protein LMO4 or its interacting partner Deaf-1.

PubMed ID: 14966286

DOI: 10.1128/mcb.24.5.2074-2082.2004

PubMed ID: 18826651

Title: Deaf-1 regulates epithelial cell proliferation and side-branching in the mammary gland.

PubMed ID: 18826651

DOI: 10.1186/1471-213x-8-94

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 22723967

Title: Contribution of DEAF1 structural domains to the interaction with the breast cancer oncogene LMO4.

PubMed ID: 22723967

DOI: 10.1371/journal.pone.0039218

PubMed ID: 24726472

Title: Mutations affecting the SAND domain of DEAF1 cause intellectual disability with severe speech impairment and behavioral problems.

PubMed ID: 24726472

DOI: 10.1016/j.ajhg.2014.03.013

Sequence Information:

  • Length: 566
  • Mass: 59633
  • Checksum: 6CC4B10E914EFD83
  • Sequence:
    • MEDSDSAAKQ LGLAEAAAVA AAAAVAAAAA AAAESEAEEP VLSRDEDSEE DADSEAERET 
RRVTAVAVMA AESGHMDMGT EALPSPDEAA AAAAAFAEVT TVTVANVGSS ADNVFTTSVA 
NAASISGHVL SGRTALQIGD SLNTEKATLI VVHTDGSIVE TTGLKGPAAP LTPGPQSPPT 
PLAPGQEKGG TKYNWDPSVY DSELPVRCRN ISGTLYKSRL GSGGRGRCIK QGENWYSPTE 
FEAMAGRASS KDWKRSIRYA GRPLQCLIQD GILNPHAASC TCAACCDDMT LSGPVRLFVP 
YKRRKKENEL PTTPVKKDSP KNITLLPATA ATTFTVTPSG QITTSGALTF DRASTVEATA 
VISESPAQGD VFAGATVQEA GVQPPCRVGH PEPHYPGYQD SCQIAPFPEA ALPTSHPKIV 
LTSLPALAVP PSTPTKAVSP TVVSGLEMSE HRSWLYLEEM VNSLLNTAQQ LKTLFEQAKQ 
ASSCREAAVT QARMQVDTER KEQSCVNCGR EAMSECTGCH KVNYCSTFCQ RKDWKDHQHV 
CGQSASVTVQ ADDVHVEESV IEKVAV

Genular Protein ID: 1171742538

Symbol: Q3TYJ5_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q3TYJ5

Database IDs:

AGR 1 ARBA 1 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 2 GO 2 Gene3D 1 InterPro 3 MGI 2 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 Pfam 1 RefSeq 1 SAM 1 SMART 1 SUPFAM 1

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

Sequence Information:

  • Length: 445
  • Mass: 47548
  • Checksum: 4BA79A9CF3F0EDCF
  • Sequence:
    • MGLAASLQRE KEVTTVTVAN VGSSADNVFT TSVANAASIS GHVLSGRTAL QIGDSLNTEK 
ATLIVVHTDG SIVETTGLKG PAAPLTPGPQ SPPTPLAPGQ EKGGTKYNWD PSVYDSELPV 
RCRNISGTLY KSRLGSGGRG RCIKQGENWY SPTEFEAMAG RASSKDWKRS IRYAGRPLQC 
LIQDGILNPH AASCTCAACC DDMTLSGPVR LFVPYKRRKK ENELPTTPVK KDSPKNITLL 
PATAATTFTV TPSGQITTSG ALTFDRASTV EATAVISESP AQGDVFAGAT VQEAGVQPPC 
RVGHPEPHYP GYQDSCQIAP FPEAALPTSH PKIVLTSLPA LAVPPSTPTK AVSPTVVSGL 
EMSEHRSWLY LEEMVNSLLN TAQQLKTLFE QAKQASSCRE AAVTQARMQV DTERKECNLV 
RIGYINTVFH QPLQCPASCG RWRML

Genular Protein ID: 2141099023

Symbol: Q80V49_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q80V49

Database IDs:

AGR 1 ARBA 1 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 2 GO 2 Gene3D 2 InterPro 3 MGI 2 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 Pfam 1 RefSeq 1 SAM 1 SMART 1 SUPFAM 1 UCSC 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 450
  • Mass: 47917
  • Checksum: FA82DB7F42C8BFF1
  • Sequence:
    • MGLAASLQRE KEVTTVTVAN VGSSADNVFT TSVANAASIS GHVLSGRTAL QIGDSLNTEK 
ATLIVVHTDG SIVETTGLKG PAAPLTPGPQ SPPTPLAPGQ EKGGTKYNWD PSVYDSELPV 
RCRNISGTLY KSRLGSGGRG RCIKQGENWY SPTEFEAMAG RASSKDWKRS IRYAGRPLQC 
LIQDGILNPH AASCTCAACC DDMTLSGPVR LFVPYKRRKK ENELPTTPVK KDSPKNITLL 
PATAATTFTV TPSGQITTSG ALTFDRASTV EATAVISESP AQGDVFAGAT VQEAGVQPPC 
RVGHPEPHYP GYQDSCQIAP FPEAALPTSH PKIVLTSLPA LAVPPSTPTK AVSPTVVSGL 
EMSEHRSWLY LEEMVNSLLN TAQQLKTLFE QAKQASSCRE AAVTQARMQV DTERKEDWKD 
HQHVCGQSAS VTVQADDVHV EESVIEKVAV

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.