Details for: GSAP

Gene ID: 54103

Symbol: GSAP

Ensembl ID: ENSG00000186088

Description: gamma-secretase activating protein

Associated with

Other Information

Genular Protein ID: 104604300

Symbol: GSAP_HUMAN

Name: Gamma-secretase-activating protein

UniProtKB Accession Codes:

A4D1B5 A4D1B6 Q3MJC0 Q8ND73 Q9UMH3 Q9Y4L9

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CTD 1 ChEMBL 1 ChiTaRS 1 DIP 1 DNASU 1 DisGeNET 1 EMBL 9 EPD 1 Ensembl 1 ExpressionAtlas 1 GO 4 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 2 KEGG 1 MANE-Select 1 MIM 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 RNAct 1 RefSeq 1 STRING 1 SignaLink 1 TopDownProteomics 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 neXtProt 1

Citations:

PubMed ID: 12853948

Title: The DNA sequence of human chromosome 7.

PubMed ID: 12853948

DOI: 10.1038/nature01782

PubMed ID: 12690205

Title: Human chromosome 7: DNA sequence and biology.

PubMed ID: 12690205

DOI: 10.1126/science.1083423

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 20811458

Title: Gamma-secretase activating protein is a therapeutic target for Alzheimer's disease.

PubMed ID: 20811458

DOI: 10.1038/nature09325

Sequence Information:

  • Length: 854
  • Mass: 97802
  • Checksum: D7B4A3A95E2E8C3B
  • Sequence:
    • MALRLVADFD LGKDVLPWLR AQRAVSEASG AGSGGADVLE NDYESLHVLN VERNGNIIYT 
YKDDKGNVVF GLYDCQTRQN ELLYTFEKDL QVFSCSVNSE RTLLAASLVQ STKEGKRNEL 
QPGSKCLTLL VEIHPVNNVK VLKAVDSYIW VQFLYPHIES HPLPENHLLL ISEEKYIEQF 
RIHVAQEDGN RVVIKNSGHL PRDRIAEDFV WAQWDMSEQR LYYIDLKKSR SILKCIQFYA 
DESYNLMFEV PLDISLSNSG FKLVNFGCDY HQYRDKFSKH LTLCVFTNHT GSLCVCYSPK 
CASWGQITYS VFYIHKGHSK TFTTSLENVG SHMTKGITFL NLDYYVAVYL PGHFFHLLNV 
QHPDLICHNL FLTGNNEMID MLPHCPLQSL SGSLVLDCCS GKLYRALLSQ SSLLQLLQNT 
CLDCEKMAAL HCALYCGQGA QFLEAQIIQW ISENVSACHS FDLIQEFIIA SSYWSVYSET 
SNMDKLLPHS SVLTWNTEIP GITLVTEDIA LPLMKVLSFK GYWEKLNSNL EYVKYAKPHF 
HYNNSVVRRE WHNLISEEKT GKRRSAAYVR NILDNAVKVI SNLEARNLGP RLTPLLQEED 
SHQRLLMGLM VSELKDHFLR HLQGVEKKKI EQMVLDYISK LLDLICHIVE TNWRKHNLHS 
WVLHFNSRGS AAEFAVFHIM TRILEATNSL FLPLPPGFHT LHTILGVQCL PLHNLLHCID 
SGVLLLTETA VIRLMKDLDN TEKNEKLKFS IIVRLPPLIG QKICRLWDHP MSSNIISRNH 
VTRLLQNYKK QPRNSMINKS SFSVEFLPLN YFIEILTDIE SSNQALYPFE GHDNVDAEFV 
EEAALKHTAM LLGL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.