Details for: Irf7

Gene ID: 54123

Symbol: Irf7

Ensembl ID: ENSMUSG00000025498

Description: interferon regulatory factor 7

Associated with

Other Information

Genular Protein ID: 45446808

Symbol: IRF7_MOUSE

Name: Interferon regulatory factor 7

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11846980

Title: Structure and function of IRF-7.

PubMed ID: 11846980

DOI: 10.1089/107999002753452700

PubMed ID: 15743772

Title: Regulatory serine residues mediate phosphorylation-dependent and phosphorylation-independent activation of interferon regulatory factor 7.

PubMed ID: 15743772

DOI: 10.1074/jbc.m411389200

PubMed ID: 15361868

Title: Interferon-alpha induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6.

PubMed ID: 15361868

DOI: 10.1038/ni1118

PubMed ID: 15800576

Title: IRF-7 is the master regulator of type-I interferon-dependent immune responses.

PubMed ID: 15800576

DOI: 10.1038/nature03464

PubMed ID: 16846591

Title: Distinct functions of IRF-3 and IRF-7 in IFN-alpha gene regulation and control of anti-tumor activity in primary macrophages.

PubMed ID: 16846591

DOI: 10.1016/j.bcp.2006.06.002

PubMed ID: 16979567

Title: Type I interferon gene induction by the interferon regulatory factor family of transcription factors.

PubMed ID: 16979567

DOI: 10.1016/j.immuni.2006.08.009

PubMed ID: 18562536

Title: Interferon regulatory factor IRF-7 induces the antiviral alpha interferon response and protects against lethal West Nile virus infection.

PubMed ID: 18562536

DOI: 10.1128/jvi.00918-08

PubMed ID: 20049431

Title: Regulation of immunity and oncogenesis by the IRF transcription factor family.

PubMed ID: 20049431

DOI: 10.1007/s00262-009-0804-6

PubMed ID: 21490621

Title: IRF7: activation, regulation, modification and function.

PubMed ID: 21490621

DOI: 10.1038/gene.2011.21

PubMed ID: 23956435

Title: Negative regulation of Nmi on virus-triggered type I IFN production by targeting IRF7.

PubMed ID: 23956435

DOI: 10.4049/jimmunol.1300740

PubMed ID: 27129230

Title: The Type I Interferon-IRF7 Axis Mediates Transcriptional Expression of Usp25 Gene.

PubMed ID: 27129230

DOI: 10.1074/jbc.m116.718080

PubMed ID: 22095711

Title: Guanylate binding protein 4 negatively regulates virus-induced type I IFN and antiviral response by targeting IFN regulatory factor 7.

PubMed ID: 22095711

DOI: 10.4049/jimmunol.1003691

Sequence Information:

  • Length: 457
  • Mass: 51222
  • Checksum: 30B102C668F56142
  • Sequence:
  • MAEVRGVQRV LFGDWLLGEV SSGQYEGLQW LNEARTVFRV PWKHFGRRDL DEEDAQIFKA 
    WAVARGRWPP SGVNLPPPEA EAAERRERRG WKTNFRCALH STGRFILRQD NSGDPVDPHK 
    VYELSRELGS TVGPATENRE EVSLSNALPT QGVSPGSFLA RENAGLQTPS PLLSSDAGDL 
    LLQVLQYSHI LESESGADPV PPQAPGQEQD RVYEEPYAAW QVEAVPSPRP QQPALTERSL 
    GFLDVTIMYK GRTVLQAVVG HPRCVFLYSP MAPAVRTSEP QPVIFPSPAE LPDQKQLHYT 
    ETLLQHVSPG LQLELRGPSL WALRMGKCKV YWEVGSPMGT TGPSTPPQLL ERNRHTPIFD 
    FSTFFRELEE FRARRRQGSP HYTIYLGFGQ DLSAGRPKEK TLILVKLEPW VCKAYLEGVQ 
    REGVSSLDSS SLGLCLSSTN SLYEDIEHFL MDLGQWP

Genular Protein ID: 1703630943

Symbol: Q3TW14_MOUSE

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

Sequence Information:

  • Length: 426
  • Mass: 47699
  • Checksum: F74D8CFAE9D71A53
  • Sequence:
  • MAEVRGVQRV LFGDWLLGEV SSGQYEGLQW LNEARTVFRV PWKHFGRRDL DEEDAQIFKA 
    WAVARGRWPP SGVNLPPPEA EAAERRERRG WKTNFRCALH STGRFILRQD NSGDPVDPHK 
    VYELSRELGS TVGPATENRE EVSLSNALPT QGVSPGSFLA RENAGLQTPS PLLSSDAGDL 
    LLQVLQYSHI LESESGADPV PPQAPERSLG FLDVTIMYKG RTVLQAVVGH PRCVFLYSPM 
    APAVRTSEPQ PVIFPSPAEL PDQKQLHYTE TLLQHVSPGL QLELRGPSLW ALRMGKCKVY 
    WEVGSPMGTT GPSTPPQLLE RNRHTPIFDF STFFRELEEF RARRRQGSPH YTIYLGFGQD 
    LSAGRPKEKT LILVKLEPWV CKAYLEGVQR EGVSSLDSSS LGLCLSSTNS LYEDIEHFLM 
    DLGQWP

Genular Protein ID: 840868256

Symbol: D3Z4U9_MOUSE

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

Sequence Information:

  • Length: 425
  • Mass: 48028
  • Checksum: 268AC3332C699201
  • Sequence:
  • MAEVRGVQRV LFGDWLLGEV SSGQYEGLQW LNEARTVFRV PWKHFGRRDL DEEDAQIFKA 
    WAVARGRWPP SGVNLPPPEA EAAERRERRG WKTNFRCALH STGRFILRQD NSGDPVDPHK 
    VYELSRELGS TVGPATENRE EVSLSNALPT QVLQYSHILE SESGADPVPP QAPGQEQDRV 
    YEEPYAAWQV EAVPSPRPQQ PALTERSLGF LDVTIMYKGR TVLQAVVGHP RCVFLYSPMA 
    PAVRTSEPQP VIFPSPAELP DQKQLHYTET LLQHVSPGLQ LELRGPSLWA LRMGKCKVYW 
    EVGSPMGTTG PSTPPQLLER NRHTPIFDFS TFFRELEEFR ARRRQGSPHY TIYLGFGQDL 
    SAGRPKEKTL ILVKLEPWVC KAYLEGVQRE GVSSLDSSSL GLCLSSTNSL YEDIEHFLMD 
    LGQWP

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.