Lsr | ENSMUSG00000001247 | NCBI 54135

Details for: Lsr

Gene ID: 54135

Symbol: Lsr

Ensembl ID: ENSMUSG00000001247

Description: lipolysis stimulated lipoprotein receptor

Associated with

Anchoring junction
(GO:0070161)
Bicellular tight junction
(GO:0005923)
Cell junction
(GO:0030054)
Chylomicron
(GO:0042627)
Epithelial structure maintenance
(GO:0010669)
Establishment of blood-brain barrier
(GO:0060856)
Establishment of skin barrier
(GO:0061436)
Lipoprotein particle receptor activity
(GO:0030228)
Lipoprotein transport
(GO:0042953)
Liver development
(GO:0001889)
Low-density lipoprotein particle
(GO:0034362)
Low-density lipoprotein particle binding
(GO:0030169)
Membrane
(GO:0016020)
Plasma membrane
(GO:0005886)
Protein binding
(GO:0005515)
Protein localization to tricellular tight junction
(GO:0061833)
Regulation of lipid metabolic process
(GO:0019216)
Tight junction
(GO:0070160)
Tricellular tight junction
(GO:0061689)
Tricellular tight junction assembly
(GO:1904274)
Very-low-density lipoprotein particle
(GO:0034361)

Other Information

Proteins

Lipolysis-stimulated receptor

Genular Protein ID: 2056805175

Symbol: LSR_MOUSE

Name: Lipolysis-stimulated receptor

UniProtKB Accession Codes:

Q99KG5 Q3TJE7 Q3UIQ9 Q61148 Q61149 Q6U816

Database IDs:

Citations:

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15265030

Title: Distribution of the lipolysis stimulated receptor in adult and embryonic murine tissues and lethality of LSR-/- embryos at 12.5 to 14.5 days of gestation.

PubMed ID: 15265030

DOI: 10.1111/j.1432-1033.2004.04223.x

PubMed ID: 17242355

Title: Large-scale phosphorylation analysis of mouse liver.

PubMed ID: 17242355

DOI: 10.1073/pnas.0609836104

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 21245199

Title: LSR defines cell corners for tricellular tight junction formation in epithelial cells.

PubMed ID: 21245199

DOI: 10.1242/jcs.072058

PubMed ID: 23239027

Title: Analysis of the 'angulin' proteins LSR, ILDR1 and ILDR2--tricellulin recruitment, epithelial barrier function and implication in deafness pathogenesis.

PubMed ID: 23239027

DOI: 10.1242/jcs.116442

PubMed ID: 24889144

Title: JNK1/2-dependent phosphorylation of angulin-1/LSR is required for the exclusive localization of angulin-1/LSR and tricellulin at tricellular contacts in EpH4 epithelial sheet.

PubMed ID: 24889144

DOI: 10.1111/gtc.12158

PubMed ID: 30250217

Title: Identification of novel loci for pediatric cholestatic liver disease defined by KIF12, PPM1F, USP53, LSR, and WDR83OS pathogenic variants.

PubMed ID: 30250217

DOI: 10.1038/s41436-018-0288-x

Sequence Information:

Length: 594
Mass: 66108
Checksum: 2ADE28BB870A001D
Sequence:

MAPAASACAG APGSHPATTI FVCLFLIIYC PDRASAIQVT VPDPYHVVIL FQPVTLHCTY 
QMSNTLTAPI VIWKYKSFCR DRVADAFSPA SVDNQLNAQL AAGNPGYNPY VECQDSVRTV 
RVVATKQGNA VTLGDYYQGR RITITGNADL TFEQTAWGDS GVYYCSVVSA QDLDGNNEAY 
AELIVLGRTS EAPELLPGFR AGPLEDWLFV VVVCLASLLF FLLLGICWCQ CCPHTCCCYV 
RCPCCPDKCC CPEALYAAGK AATSGVPSIY APSIYTHLSP AKTPPPPPAM IPMRPPYGYP 
GDFDRTSSVG GHSSQVPLLR EVDGSVSSEV RSGYRIQANQ QDDSMRVLYY MEKELANFDP 
SRPGPPNGRV ERAMSEVTSL HEDDWRSRPS RAPALTPIRD EEWNRHSPRS PRTWEQEPLQ 
EQPRGGWGSG RPRARSVDAL DDINRPGSTE SGRSSPPSSG RRGRAYAPPR SRSRDDLYDP 
DDPRDLPHSR DPHYYDDLRS RDPRADPRSR QRSHDPRDAG FRSRDPQYDG RLLEEALKKK 
GAGERRRVYR EEEEEEEEGH YPPAPPPYSE TDSQASRERR MKKNLALSRE SLVV

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Lsr

Associated with

Other Information

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Distribution of the lipolysis stimulated receptor in adult and embryonic murine tissues and lethality of LSR-/- embryos at 12.5 to 14.5 days of gestation. PubMed ID: 15265030

Large-scale phosphorylation analysis of mouse liver. PubMed ID: 17242355

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

LSR defines cell corners for tricellular tight junction formation in epithelial cells. PubMed ID: 21245199

Analysis of the 'angulin' proteins LSR, ILDR1 and ILDR2--tricellulin recruitment, epithelial barrier function and implication in deafness pathogenesis. PubMed ID: 23239027

JNK1/2-dependent phosphorylation of angulin-1/LSR is required for the exclusive localization of angulin-1/LSR and tricellulin at tricellular contacts in EpH4 epithelial sheet. PubMed ID: 24889144

Identification of novel loci for pediatric cholestatic liver disease defined by KIF12, PPM1F, USP53, LSR, and WDR83OS pathogenic variants. PubMed ID: 30250217