Details for: DCUN1D1

Gene ID: 54165

Symbol: DCUN1D1

Ensembl ID: ENSG00000043093

Description: defective in cullin neddylation 1 domain containing 1

Associated with

Other Information

Genular Protein ID: 1465192577

Symbol: DCNL1_HUMAN

Name: DCUN1 domain-containing protein 1

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10777668

Title: Cloning and expression analysis of a novel gene, RP42, mapping to an autism susceptibility locus on 6q16.

PubMed ID: 10777668

DOI: 10.1006/geno.2000.6126

PubMed ID: 17018598

Title: Squamous cell carcinoma related oncogene/DCUN1D1 is highly conserved and activated by amplification in squamous cell carcinomas.

PubMed ID: 17018598

DOI: 10.1158/0008-5472.can-06-2074

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12796399

Title: The role of novel oncogenes squamous cell carcinoma-related oncogene and phosphatidylinositol 3-kinase p110alpha in squamous cell carcinoma of the oral tongue.

PubMed ID: 12796399

PubMed ID: 15123463

Title: Squamous cell carcinoma related oncogene regulates angiogenesis through vascular endothelial growth factor-A.

PubMed ID: 15123463

DOI: 10.1245/aso.2004.03.014

PubMed ID: 15511464

Title: SCCRO expression correlates with invasive progression in bronchioloalveolar carcinoma.

PubMed ID: 15511464

DOI: 10.1016/j.athoracsur.2004.05.056

PubMed ID: 15657565

Title: Squamous cell carcinoma-related oncogene is highly expressed in developing, normal, and adenomatous adrenal tissue but not in aggressive adrenocortical carcinomas.

PubMed ID: 15657565

DOI: 10.1016/j.surg.2004.06.041

PubMed ID: 15623817

Title: Two-step differential expression analysis reveals a new set of genes involved in thyroid oncocytic tumors.

PubMed ID: 15623817

DOI: 10.1210/jc.2004-1337

PubMed ID: 18826954

Title: SCCRO (DCUN1D1) is an essential component of the E3 complex for neddylation.

PubMed ID: 18826954

DOI: 10.1074/jbc.m804440200

PubMed ID: 19617556

Title: The human Dcn1-like protein DCNL3 promotes Cul3 neddylation at membranes.

PubMed ID: 19617556

DOI: 10.1073/pnas.0812528106

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23401859

Title: DCNL1 functions as a substrate sensor and activator of cullin 2-RING ligase.

PubMed ID: 23401859

DOI: 10.1128/mcb.01342-12

PubMed ID: 23201271

Title: Structural conservation of distinctive N-terminal acetylation-dependent interactions across a family of mammalian NEDD8 ligation enzymes.

PubMed ID: 23201271

DOI: 10.1016/j.str.2012.10.013

PubMed ID: 25349211

Title: SCCRO3 (DCUN1D3) antagonizes the neddylation and oncogenic activity of SCCRO (DCUN1D1).

PubMed ID: 25349211

DOI: 10.1074/jbc.m114.585505

PubMed ID: 26906416

Title: Characterization of the mammalian family of DCN-type NEDD8 E3 ligases.

PubMed ID: 26906416

DOI: 10.1242/jcs.181784

PubMed ID: 30587576

Title: Coupled monoubiquitylation of the co-E3 ligase DCNL1 by Ariadne-RBR E3 ubiquitin ligases promotes cullin-RING ligase complex remodeling.

PubMed ID: 30587576

DOI: 10.1074/jbc.ra118.005861

PubMed ID: 21940857

Title: N-terminal acetylation acts as an avidity enhancer within an interconnected multiprotein complex.

PubMed ID: 21940857

DOI: 10.1126/science.1209307

PubMed ID: 28581483

Title: Blocking an N-terminal acetylation-dependent protein interaction inhibits an E3 ligase.

PubMed ID: 28581483

DOI: 10.1038/nchembio.2386

Sequence Information:

  • Length: 259
  • Mass: 30124
  • Checksum: F3709235E0610C54
  • Sequence:
  • MNKLKSSQKD KVRQFMIFTQ SSEKTAVSCL SQNDWKLDVA TDNFFQNPEL YIRESVKGSL 
    DRKKLEQLYN RYKDPQDENK IGIDGIQQFC DDLALDPASI SVLIIAWKFR AATQCEFSKQ 
    EFMDGMTELG CDSIEKLKAQ IPKMEQELKE PGRFKDFYQF TFNFAKNPGQ KGLDLEMAIA 
    YWNLVLNGRF KFLDLWNKFL LEHHKRSIPK DTWNLLLDFS TMIADDMSNY DEEGAWPVLI 
    DDFVEFARPQ IAGTKSTTV

Genular Protein ID: 2698058455

Symbol: B4DM76_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 219
  • Mass: 25611
  • Checksum: 7732BD40EF2677AD
  • Sequence:
  • MNKLKSSQKD KVRQFMIFTQ SSEKTAVSCL SQNDWKLDVA TDNFFQNPEL YIRESVKGSL 
    DRKKLEQLYN RYKDPQDENK IGMDGMTELG CDSIEKLKAQ TPKMEQELKE PGRFKDFYQF 
    TFNFAKNPGQ KGLDLEMAIA YWNLVLNGRF KFLDLWNKFL LEHHKRSIPK DTWNLLLDFS 
    TMIADDMSNY DEEGAWPVLI DDFVEFARPQ IAGTKSTTV

Genular Protein ID: 968305940

Symbol: C9JVE2_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 16641997

Title: The DNA sequence, annotation and analysis of human chromosome 3.

PubMed ID: 16641997

DOI: 10.1038/nature04728

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

Sequence Information:

  • Length: 244
  • Mass: 28305
  • Checksum: 641E83EC03F5498E
  • Sequence:
  • MIFTQSSEKT AVSCLSQNDW KLDVATDNFF QNPELYIRES VKGSLDRKKL EQLYNRYKDP 
    QDENKIGIDG IQQFCDDLAL DPASISVLII AWKFRAATQC EFSKQEFMDG MTELGCDSIE 
    KLKAQIPKME QELKEPGRFK DFYQFTFNFA KNPGQKGLDL EMAIAYWNLV LNGRFKFLDL 
    WNKFLLEHHK RSIPKDTWNL LLDFSTMIAD DMSNYDEEGA WPVLIDDFVE FARPQIAGTK 
    STTV

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.