Rragc | ENSMUSG00000028646 | NCBI 54170

Details for: Rragc

Gene ID: 54170

Symbol: Rragc

Ensembl ID: ENSMUSG00000028646

Description: Ras-related GTP binding C

Associated with

Amino acids regulate mtorc1
(R-MMU-9639288)
Autophagy
(R-MMU-9612973)
Cellular responses to stimuli
(R-MMU-8953897)
Cellular responses to stress
(R-MMU-2262752)
Energy dependent regulation of mtor by lkb1-ampk
(R-MMU-380972)
Gene expression (transcription)
(R-MMU-74160)
Generic transcription pathway
(R-MMU-212436)
Intracellular signaling by second messengers
(R-MMU-9006925)
Macroautophagy
(R-MMU-1632852)
Mtorc1-mediated signalling
(R-MMU-166208)
Mtor signalling
(R-MMU-165159)
Pip3 activates akt signaling
(R-MMU-1257604)
Pten regulation
(R-MMU-6807070)
Regulation of pten gene transcription
(R-MMU-8943724)
Rna polymerase ii transcription
(R-MMU-73857)
Signal transduction
(R-MMU-162582)
Tp53 regulates metabolic genes
(R-MMU-5628897)
Transcriptional regulation by tp53
(R-MMU-3700989)
Cellular response to amino acid starvation
(GO:0034198)
Cellular response to nutrient levels
(GO:0031669)
Cellular response to starvation
(GO:0009267)
Cytoplasm
(GO:0005737)
Enzyme-substrate adaptor activity
(GO:0140767)
Fnip-folliculin ragc/d gap
(GO:1990877)
Gdp binding
(GO:0019003)
Gtpase activity
(GO:0003924)
Gtpase binding
(GO:0051020)
Gtp binding
(GO:0005525)
Gtr1-gtr2 gtpase complex
(GO:1990131)
Hydrolase activity
(GO:0016787)
Intracellular membrane-bounded organelle
(GO:0043231)
Lysosomal membrane
(GO:0005765)
Lysosome
(GO:0005764)
Membrane
(GO:0016020)
Molecular adaptor activity
(GO:0060090)
Negative regulation of autophagy
(GO:0010507)
Nucleoplasm
(GO:0005654)
Nucleotide binding
(GO:0000166)
Nucleus
(GO:0005634)
Positive regulation of torc1 signaling
(GO:1904263)
Protein-membrane adaptor activity
(GO:0043495)
Protein binding
(GO:0005515)
Protein heterodimerization activity
(GO:0046982)
Protein localization to lysosome
(GO:0061462)
Protein localization to membrane
(GO:0072657)
Regulation of torc1 signaling
(GO:1903432)
Regulation of tor signaling
(GO:0032006)
Response to amino acid
(GO:0043200)

Other Information

Proteins

Ras-related GTP-binding protein C

Genular Protein ID: 1429796426

Symbol: RRAGC_MOUSE

Name: Ras-related GTP-binding protein C

UniProtKB Accession Codes:

Q99K70 A2A7K7 Q3TL69 Q6IQZ6 Q8CFT7 Q9Z124

Database IDs:

Citations:

PubMed ID: 10660099

Title: A new member of the GTPase superfamily that is upregulated in highly metastatic cells.

PubMed ID: 10660099

DOI: 10.1016/s0304-3835(99)00285-2

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 19144319

Title: The phagosomal proteome in interferon-gamma-activated macrophages.

PubMed ID: 19144319

DOI: 10.1016/j.immuni.2008.11.006

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 25259925

Title: Sestrins function as guanine nucleotide dissociation inhibitors for Rag GTPases to control mTORC1 signaling.

PubMed ID: 25259925

DOI: 10.1016/j.cell.2014.08.038

PubMed ID: 29644770

Title: TMEM55B contributes to lysosomal homeostasis and amino acid-induced mTORC1 activation.

PubMed ID: 29644770

DOI: 10.1111/gtc.12583

PubMed ID: 30595499

Title: Lysosomal signaling licenses embryonic stem cell differentiation via inactivation of Tfe3.

PubMed ID: 30595499

DOI: 10.1016/j.stem.2018.11.021

PubMed ID: 29158492

Title: Structural basis for the assembly of the Ragulator-Rag GTPase complex.

PubMed ID: 29158492

DOI: 10.1038/s41467-017-01762-3

Sequence Information:

Length: 398
Mass: 44121
Checksum: 094F670E44B37A25
Sequence:

MSLQYGAEET PLAGSYGAAD SFPKDFGYGV EEEEEEAAAG GGGGAGAGGG CGPGGADSSK 
PRILLMGLRR SGKSSIQKVV FHKMSPNETL FLESTNKIYK DDISNSSFVN FQIWDFPGQM 
DFFDPTFDYE MIFRGTGALI YVIDAQDDYM EALTRLHITV SKAYKVNPDM NFEVFIHKVD 
GLSDDHKIET QRDIHQRAND DLADAGLEKL HLSFYLTSIY DHSIFEAFSK VVQKLIPQLP 
TLENLLNIFI SNSGIEKAFL FDVVSKIYIA TDSSPVDMQS YELCCDMIDV VIDVSCIYGL 
KEDGSGSAYD KESMAIIKLN NTTVLYLKEV TKFLALVCIL REESFERKGL IDYNFHCFRK 
AIHEVFEVGV TSHRSCSHQT SAPSLKALAH NGTPRNAI

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Rragc

Associated with

Other Information

A new member of the GTPase superfamily that is upregulated in highly metastatic cells. PubMed ID: 10660099

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

The phagosomal proteome in interferon-gamma-activated macrophages. PubMed ID: 19144319

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Sestrins function as guanine nucleotide dissociation inhibitors for Rag GTPases to control mTORC1 signaling. PubMed ID: 25259925

TMEM55B contributes to lysosomal homeostasis and amino acid-induced mTORC1 activation. PubMed ID: 29644770

Lysosomal signaling licenses embryonic stem cell differentiation via inactivation of Tfe3. PubMed ID: 30595499

Structural basis for the assembly of the Ragulator-Rag GTPase complex. PubMed ID: 29158492