Details for: Cd160

Gene ID: 54215

Symbol: Cd160

Ensembl ID: ENSMUSG00000038304

Description: CD160 antigen

Associated with

  • Adaptive immune system
    (R-MMU-1280218)
  • Immune system
    (R-MMU-168256)
  • Immunoregulatory interactions between a lymphoid and a non-lymphoid cell
    (R-MMU-198933)
  • Activating mhc class i receptor activity
    (GO:0032397)
  • Adaptive immune response
    (GO:0002250)
  • Defense response to gram-negative bacterium
    (GO:0050829)
  • Extracellular region
    (GO:0005576)
  • Immune system process
    (GO:0002376)
  • Innate immune response
    (GO:0045087)
  • Kinase binding
    (GO:0019900)
  • Membrane
    (GO:0016020)
  • Mhc class ib receptor activity
    (GO:0032394)
  • Mhc class i protein complex binding
    (GO:0023024)
  • Mhc class i receptor activity
    (GO:0032393)
  • Mucosal immune response
    (GO:0002385)
  • Negative regulation of adaptive immune memory response
    (GO:1905675)
  • Negative regulation of angiogenesis
    (GO:0016525)
  • Negative regulation of cd4-positive, alpha-beta t cell costimulation
    (GO:1900280)
  • Negative regulation of t cell receptor signaling pathway
    (GO:0050860)
  • Phosphatidylinositol 3-kinase/protein kinase b signal transduction
    (GO:0043491)
  • Plasma membrane
    (GO:0005886)
  • Positive regulation of endothelial cell apoptotic process
    (GO:2000353)
  • Positive regulation of natural killer cell cytokine production
    (GO:0002729)
  • Positive regulation of natural killer cell degranulation
    (GO:0043323)
  • Positive regulation of natural killer cell mediated cytotoxicity
    (GO:0045954)
  • Positive regulation of natural killer cell mediated immune response to tumor cell
    (GO:0002857)
  • Positive regulation of type ii interferon production
    (GO:0032729)
  • Protein binding
    (GO:0005515)
  • Regulation of adaptive immune response
    (GO:0002819)
  • Side of membrane
    (GO:0098552)
  • Signaling receptor binding
    (GO:0005102)
  • T cell costimulation
    (GO:0031295)
  • Transmembrane signaling receptor activity
    (GO:0004888)

Other Information

Genular Protein ID: 1272628469

Symbol: BY55_MOUSE

Name: CD160 antigen

UniProtKB Accession Codes:

O88875 Q8C9H4

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CCDS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 4 Ensembl 2 ExpressionAtlas 1 GO 25 Gene3D 1 GeneTree 1 Genevisible 1 GlyCosmos 1 GlyGen 1 InParanoid 1 InterPro 6 KEGG 1 MGI 2 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRO 1 PROSITE 1 PROSITE-ProRule 1 PaxDb 1 Pfam 1 PhosphoSitePlus 1 Proteomes 1 ProteomicsDB 1 RNAct 1 Reactome 1 RefSeq 2 SMART 1 SMR 1 STRING 1 SUPFAM 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1

Citations:

PubMed ID: 9743336

Title: Cloning of BY55, a novel Ig superfamily member expressed on NK cells, CTL, and intestinal intraepithelial lymphocytes.

PubMed ID: 9743336

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 16177084

Title: Murine CD160, Ig-like receptor on NK cells and NKT cells, recognizes classical and nonclassical MHC class I and regulates NK cell activation.

PubMed ID: 16177084

DOI: 10.4049/jimmunol.175.7.4426

PubMed ID: 18193050

Title: CD160 inhibits activation of human CD4+ T cells through interaction with herpesvirus entry mediator.

PubMed ID: 18193050

DOI: 10.1038/ni1554

PubMed ID: 22801499

Title: HVEM signalling at mucosal barriers provides host defence against pathogenic bacteria.

PubMed ID: 22801499

DOI: 10.1038/nature11242

PubMed ID: 25711213

Title: CD160 is essential for NK-mediated IFN-gamma production.

PubMed ID: 25711213

DOI: 10.1084/jem.20131601

Sequence Information:

  • Length: 185
  • Mass: 20570
  • Checksum: 37071CB339E032E2
  • Sequence:
    • MQRILMAPGQ SCCALAILLA IVNFQHGGCI HVTSSASQKG GRLDLTCTLW HKKDEAEGLI 
LFWCKDNPWN CSPETNLEQL RVKRDPETDG ITEKSSQLVF TIEQATPSDS GTYQCCARSQ 
KPEIYIHGHF LSVLVTGNHT EIRQRQRSHP DFSHINGTLS SGFLQVKAWG MLVTSLVALQ 
ALYTL

Genular Protein ID: 2349501489

Symbol: E9Q0X3_MOUSE

Name: N/A

UniProtKB Accession Codes:

E9Q0X3

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 EPD 2 Ensembl 2 ExpressionAtlas 1 GO 2 Gene3D 1 GeneTree 1 Genevisible 1 HOGENOM 1 InterPro 6 MGI 2 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 Pfam 1 Proteomes 2 ProteomicsDB 2 RefSeq 1 SAM 1 SMART 1 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

Sequence Information:

  • Length: 141
  • Mass: 15669
  • Checksum: B51ADD5B8E451275
  • Sequence:
    • MQRILMAPGQ SCCALAILLA IVNFQHGGCI HVTSSASQKG GRLDLTCTLW HKKDEAEGLI 
LFWCKDNPWN CSPETNLEQL RVKRDPETDG ITEKSSQLVF TIEQATPSDS GTYQCCARSQ 
KPEIYIHGHF LSVLVTALYT L

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.