Chrnb2 | ENSRNOG00000020778 | NCBI 54239

Details for: Chrnb2

Gene ID: 54239

Symbol: Chrnb2

Ensembl ID: ENSRNOG00000020778

Description: cholinergic receptor nicotinic beta 2 subunit

Associated with

Acetylcholine binding and downstream events
(R-RNO-181431)
Highly calcium permeable nicotinic acetylcholine receptors
(R-RNO-629597)
Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
(R-RNO-629594)
Highly sodium permeable postsynaptic acetylcholine nicotinic receptors
(R-RNO-629587)
Neuronal system
(R-RNO-112316)
Neurotransmitter receptors and postsynaptic signal transmission
(R-RNO-112314)
Postsynaptic nicotinic acetylcholine receptors
(R-RNO-622327)
Presynaptic nicotinic acetylcholine receptors
(R-RNO-622323)
Transmission across chemical synapses
(R-RNO-112315)
Acetylcholine-gated channel complex
(GO:0005892)
Acetylcholine-gated monoatomic cation-selective channel activity
(GO:0022848)
Acetylcholine binding
(GO:0042166)
Acetylcholine receptor activity
(GO:0015464)
Acetylcholine receptor signaling pathway
(GO:0095500)
Action potential
(GO:0001508)
Associative learning
(GO:0008306)
B cell activation
(GO:0042113)
B cell proliferation
(GO:0042100)
Behavioral response to nicotine
(GO:0035095)
Calcium ion transport
(GO:0006816)
Central nervous system neuron axonogenesis
(GO:0021955)
Central nervous system projection neuron axonogenesis
(GO:0021952)
Chemical synaptic transmission
(GO:0007268)
Cholinergic synapse
(GO:0098981)
Cognition
(GO:0050890)
Conditioned taste aversion
(GO:0001661)
Dopaminergic synapse
(GO:0098691)
Dopamine secretion
(GO:0014046)
Establishment of localization in cell
(GO:0051649)
Excitatory postsynaptic potential
(GO:0060079)
External side of plasma membrane
(GO:0009897)
Heterocyclic compound binding
(GO:1901363)
Lateral geniculate nucleus development
(GO:0021771)
Learning
(GO:0007612)
Locomotory behavior
(GO:0007626)
Membrane depolarization
(GO:0051899)
Memory
(GO:0007613)
Monoatomic ion transmembrane transport
(GO:0034220)
Negative regulation of neuronal action potential
(GO:1904456)
Nervous system process
(GO:0050877)
Neuronal action potential
(GO:0019228)
Neuron projection
(GO:0043005)
Optic nerve morphogenesis
(GO:0021631)
Plasma membrane
(GO:0005886)
Plasma membrane raft
(GO:0044853)
Positive regulation of b cell proliferation
(GO:0030890)
Positive regulation of dopamine secretion
(GO:0033603)
Positive regulation of synaptic transmission, dopaminergic
(GO:0032226)
Postsynaptic specialization membrane
(GO:0099634)
Presynapse
(GO:0098793)
Presynaptic membrane
(GO:0042734)
Presynaptic modulation of chemical synaptic transmission
(GO:0099171)
Protein-containing complex
(GO:0032991)
Protein-containing complex binding
(GO:0044877)
Protein binding
(GO:0005515)
Quaternary ammonium group binding
(GO:0050997)
Regulation of circadian sleep/wake cycle, non-rem sleep
(GO:0045188)
Regulation of circadian sleep/wake cycle, rem sleep
(GO:0042320)
Regulation of dendrite morphogenesis
(GO:0048814)
Regulation of dopamine metabolic process
(GO:0042053)
Regulation of dopamine secretion
(GO:0014059)
Regulation of membrane potential
(GO:0042391)
Regulation of synapse assembly
(GO:0051963)
Regulation of synaptic transmission, dopaminergic
(GO:0032225)
Response to acetylcholine
(GO:1905144)
Response to cocaine
(GO:0042220)
Response to ethanol
(GO:0045471)
Response to hypoxia
(GO:0001666)
Response to nicotine
(GO:0035094)
Sensory perception of pain
(GO:0019233)
Sensory perception of sound
(GO:0007605)
Signal transduction
(GO:0007165)
Smooth muscle contraction
(GO:0006939)
Social behavior
(GO:0035176)
Synapse
(GO:0045202)
Synaptic transmission, cholinergic
(GO:0007271)
Synaptic transmission involved in micturition
(GO:0060084)
Transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
(GO:1904315)
Vestibulocochlear nerve development
(GO:0021562)
Visual learning
(GO:0008542)
Visual perception
(GO:0007601)

Other Information

Proteins

Neuronal acetylcholine receptor subunit beta-2

Genular Protein ID: 4273216262

Symbol: ACHB2_RAT

Name: Neuronal acetylcholine receptor subunit beta-2

UniProtKB Accession Codes:

P12390 Q53YK1

Database IDs:

Citations:

PubMed ID: 3272154

Title: Primary structure and expression of beta 2: a novel subunit of neuronal nicotinic acetylcholine receptors.

PubMed ID: 3272154

DOI: 10.1016/0896-6273(88)90208-5

PubMed ID: 2444984

Title: Functional expression of two neuronal nicotinic acetylcholine receptors from cDNA clones identifies a gene family.

PubMed ID: 2444984

DOI: 10.1073/pnas.84.21.7763

PubMed ID: 15609996

Title: Alpha-conotoxins ImI and ImII target distinct regions of the human alpha7 nicotinic acetylcholine receptor and distinguish human nicotinic receptor subtypes.

PubMed ID: 15609996

DOI: 10.1021/bi048918g

PubMed ID: 15929983

Title: Beta2 subunit contribution to 4/7 alpha-conotoxin binding to the nicotinic acetylcholine receptor.

PubMed ID: 15929983

DOI: 10.1074/jbc.m504229200

PubMed ID: 16964981

Title: Determinants of alpha-conotoxin BuIA selectivity on the nicotinic acetylcholine receptor beta subunit.

PubMed ID: 16964981

DOI: 10.1021/bi0611715

Sequence Information:

Length: 500
Mass: 56909
Checksum: 54C007A48225931C
Sequence:

MAGHSNSMAL FSFSLLWLCS GVLGTDTEER LVEHLLDPSR YNKLIRPATN GSELVTVQLM 
VSLAQLISVH EREQIMTTNV WLTQEWEDYR LTWKPEDFDN MKKVRLPSKH IWLPDVVLYN 
NADGMYEVSF YSNAVVSYDG SIFWLPPAIY KSACKIEVKH FPFDQQNCTM KFRSWTYDRT 
EIDLVLKSDV ASLDDFTPSG EWDIIALPGR RNENPDDSTY VDITYDFIIR RKPLFYTINL 
IIPCVLITSL AILVFYLPSD CGEKMTLCIS VLLALTVFLL LISKIVPPTS LDVPLVGKYL 
MFTMVLVTFS IVTSVCVLNV HHRSPTTHTM APWVKVVFLE KLPTLLFLQQ PRHRCARQRL 
RLRRRQRERE GAGALFFREG PAADPCTCFV NPASVQGLAG AFRAEPTAAG PGRSVGPCSC 
GLREAVDGVR FIADHMRSED DDQSVREDWK YVAMVIDRLF LWIFVFVCVF GTVGMFLQPL 
FQNYTATTFL HPDHSAPSSK

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Chrnb2

Associated with

Other Information

Primary structure and expression of beta 2: a novel subunit of neuronal nicotinic acetylcholine receptors. PubMed ID: 3272154

Functional expression of two neuronal nicotinic acetylcholine receptors from cDNA clones identifies a gene family. PubMed ID: 2444984

Alpha-conotoxins ImI and ImII target distinct regions of the human alpha7 nicotinic acetylcholine receptor and distinguish human nicotinic receptor subtypes. PubMed ID: 15609996