Inpp5d | ENSRNOG00000017020 | NCBI 54259

Details for: Inpp5d

Gene ID: 54259

Symbol: Inpp5d

Ensembl ID: ENSRNOG00000017020

Description: inositol polyphosphate-5-phosphatase D

Associated with

Adaptive immune system
(R-RNO-1280218)
Cell surface interactions at the vascular wall
(R-RNO-202733)
Cytokine signaling in immune system
(R-RNO-1280215)
Downstream tcr signaling
(R-RNO-202424)
Hemostasis
(R-RNO-109582)
Immune system
(R-RNO-168256)
Inositol phosphate metabolism
(R-RNO-1483249)
Interleukin-2 family signaling
(R-RNO-451927)
Interleukin-3, interleukin-5 and gm-csf signaling
(R-RNO-512988)
Interleukin receptor shc signaling
(R-RNO-912526)
Metabolism
(R-RNO-1430728)
Metabolism of lipids
(R-RNO-556833)
Pecam1 interactions
(R-RNO-210990)
Phospholipid metabolism
(R-RNO-1483257)
Pi metabolism
(R-RNO-1483255)
Signaling by interleukins
(R-RNO-449147)
Synthesis of ip3 and ip4 in the cytosol
(R-RNO-1855204)
Synthesis of pips at the plasma membrane
(R-RNO-1660499)
Tcr signaling
(R-RNO-202403)
Actin filament
(GO:0005884)
Apoptotic process
(GO:0006915)
Biological_process
(GO:0008150)
Cortical cytoskeleton
(GO:0030863)
Cytoskeleton
(GO:0005856)
Cytosol
(GO:0005829)
Determination of adult lifespan
(GO:0008340)
Immunoglobulin mediated immune response
(GO:0016064)
Inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity
(GO:0052659)
Inositol-1,4,5-trisphosphate 5-phosphatase activity
(GO:0052658)
Inositol-4,5-bisphosphate 5-phosphatase activity
(GO:0030487)
Inositol-polyphosphate 5-phosphatase activity
(GO:0004445)
Inositol phosphate phosphatase activity
(GO:0052745)
Intracellular signal transduction
(GO:0035556)
Membrane
(GO:0016020)
Membrane raft
(GO:0045121)
Negative regulation of b cell activation
(GO:0050869)
Negative regulation of b cell proliferation
(GO:0030889)
Negative regulation of bone resorption
(GO:0045779)
Negative regulation of cell population proliferation
(GO:0008285)
Negative regulation of granulocyte differentiation
(GO:0030853)
Negative regulation of immune response
(GO:0050777)
Negative regulation of interleukin-6 production
(GO:0032715)
Negative regulation of monocyte differentiation
(GO:0045656)
Negative regulation of neutrophil differentiation
(GO:0045659)
Negative regulation of osteoclast differentiation
(GO:0045671)
Negative regulation of signal transduction
(GO:0009968)
Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity
(GO:0034485)
Phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity
(GO:0004439)
Phosphatidylinositol dephosphorylation
(GO:0046856)
Phosphatidylinositol trisphosphate phosphatase activity
(GO:0034594)
Plasma membrane
(GO:0005886)
Positive regulation of apoptotic process
(GO:0043065)
Positive regulation of b cell differentiation
(GO:0045579)
Positive regulation of erythrocyte differentiation
(GO:0045648)
Positive regulation of lymphocyte differentiation
(GO:0045621)
Protein binding
(GO:0005515)
Ptb domain binding
(GO:0051425)
Regulation of immune response
(GO:0050776)
Sh3 domain binding
(GO:0017124)

Other Information

Proteins

Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1

Genular Protein ID: 2101834282

Symbol: SHIP1_RAT

Name: Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1

UniProtKB Accession Codes:

P97573

Database IDs:

Citations:

PubMed ID: 8910587

Title: The inositol 5'-phosphatase SHIP binds to immunoreceptor signaling motifs and responds to high affinity IgE receptor aggregation.

PubMed ID: 8910587

DOI: 10.1074/jbc.271.46.29271

PubMed ID: 22673903

Title: Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.

PubMed ID: 22673903

DOI: 10.1038/ncomms1871

Sequence Information:

Length: 1190
Mass: 133593
Checksum: 85DD4F2190F98700
Sequence:

MPAMVPGWNH GNITRSKAEE LLSRAGKDGS FLVRASESIP RAYALCVLFR NCVYTYRILP 
NEDDKFTVQA SEGVPMRFFT KLDQLIEFYK KENMGLVTHL QFPVPLEEED AIDEPEEDTE 
SVMSPPELPP RNIPVSGGPC EAKDLPLPTE NPRAPEVTRL SLSETLFQRL QSMDTSGLPE 
EHLKAIQDYL STQLMLDSDF LKTGSSNLPH LKKLTSLLCK ELHGEVIRTL PSLESLQRLF 
DQQLSPGLRP RPQVPGEANP ITMVAKLSQL TSLLSSIEDK VKALLHEGSE STNRRSLIPP 
VTFEVKSESL GIPQKMHLKV DVESGKLIIK KSRDGSEDKF YSHKKILQLI KSQKFLNKLV 
ILVETEKEKI LRKEYVFSDS KKREGFCQLL QQMKNKHSEQ SEPDMITIFI GTWNMGNAPP 
PKKITSWFLS KGQGKTRDDS ADYIPHDIYV IGTQEDPLGE KEWLEILRHS LQEVTSMTFK 
TVAIHTLWNI RIVVLAKPEH ENRISHICTD NVKTGIANTL GNKGAVGVSF MFNGTSLGFV 
NSHLTSGSEK KLRRNQNYMN ILRFLALGDK KLSPFNITHR FTHLFWLGDL NYRVELPTWE 
AEAIIQKIKQ QQYSDLLAHD QLLLERKEQE VFLHFEEEEI TFAPTYRFER LTRDKYAYTK 
QKATGMKYNL PSWCDRVLWK SYPLVHVVCQ SYGSTSDIMT SDHSPVFATF EAGVTSQFVS 
KNGPGAVDSQ GQIEFLACYA TLKTKSQTKF YLELHSSCLE SFVKSQEGEN EEGDEGELVV 
RFGETLPKLK PIISDPEYLL DQHILISIKS SDSDESYGEG CIALRLETTE SQLPIYTPLT 
HHGEMTGHFR GEIKLQTSEG KMREKLYDFV KTERDESSGM KCLKNLTSHD PMRQWEPAGR 
VPACGISSLN EIINPNYIGM GPFGQPLHGK STLSPDQQLT AWSYDQLPKD SSLGPGRGEG 
PPTPPSQPPL SPKKFSSSTA NRGSCPRVQE TRPGDLGKVE ALPQEDLPLT KPEMFENPLY 
GSVSPFPKLV PRKEQESPKM MRKEPPPCPD PGVSSPSIML PKAQEVENVK GTSKQAPVPV 
FGPTPRIRSF TCSSSAEGRM PSGDKSQGKP KAPASSQAPV PVKRPVKPSR SEMSQQTTPI 
PAPRPPLPVK SPAVLQLQHS KGRDYRDNTE LPHHGKHRQE ESLLGRTAMQ

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.