Details for: Pfkfb4

Gene ID: 54283

Symbol: Pfkfb4

Ensembl ID: ENSRNOG00000020656

Description: 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4

Associated with

Other Information

Genular Protein ID: 3372457170

Symbol: F264_RAT

Name: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4

UniProtKB Accession Codes:

P25114

Database IDs:

AGR 1 AlphaFoldDB 1 BRENDA 2 Bgee 1 CDD 1 CTD 1 ChEBI 31 ComplexPortal 1 DIP 1 EC 2 EMBL 1 Ensembl 4 EvolutionaryTrace 1 ExpressionAtlas 1 GO 6 Gene3D 2 GeneTree 1 Genevisible 1 HOGENOM 1 InParanoid 1 InterPro 6 KEGG 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PDB 6 PDBsum 3 PIR 1 PIRSF 1 PRINTS 1 PRO 1 PROSITE 1 PaxDb 1 Pfam 2 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 RGD 1 Reactome 1 RefSeq 3 Rhea 4 SABIO-RK 1 SMART 1 SMR 1 STRING 1 SUPFAM 2 TreeFam 1 UCSC 1 UniProtKB 3 eggNOG 1 jPOST 1

Citations:

PubMed ID: 1651918

Title: Molecular cloning of the DNA and expression and characterization of rat testes fructose-6-phosphate,2-kinase:fructose-2,6-bisphosphatase.

PubMed ID: 1651918

DOI: 10.1016/s0021-9258(18)98475-9

PubMed ID: 8805587

Title: The crystal structure of the bifunctional enzyme 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase reveals distinct domain homologies.

PubMed ID: 8805587

DOI: 10.1016/s0969-2126(96)00109-8

PubMed ID: 9890980

Title: Crystal structure of the H256A mutant of rat testis fructose-6-phosphate,2-kinase/fructose-2,6-bisphosphatase. Fructose 6-phosphate in the active site leads to mechanisms for both mutant and wild type bisphosphatase activities.

PubMed ID: 9890980

DOI: 10.1074/jbc.274.4.2176

Sequence Information:

  • Length: 469
  • Mass: 54155
  • Checksum: E3D0AF34D3A09CA6
  • Sequence:
    • MASPRELTQN PLKKIWMPYS NGRPALHASQ RGVCMTNCPT LIVMVGLPAR GKTYISKKLT 
RYLNWIGVPT REFNVGQYRR DMVKTYKSFE FFLPDNEEGL KIRKQCALAA LNDVRKFLSE 
EGGHVAVFDA TNTTRERRAM IFNFGEQNGY KTFFVESICV DPEVIAANIV QVKLGSPDYV 
NRDSDEATED FMRRIECYEN SYESLDEEQD RDLSYIKIMD VGQSYVVNRV ADHIQSRIVY 
YLMNIHVTPR SIYLCRHGES ELNLKGRIGG DPGLSPRGRE FSKHLAQFIS DQNIKDLKVW 
TSQMKRTIQT AEALSVPYEQ WKVLNEIDAG VCEEMTYEEI QDHYPLEFAL RDQDKYRYRY 
PKGESYEDLV QRLEPVIMEL ERQENVLVIC HQAVMRCLLA YFLDKAAEEL PYLKCPLHTV 
LKLTPVAYGC KVESIFLNVA AVNTHRDRPQ NVDISRPSEE ALVTVPAHQ

Genular Protein ID: 780334530

Symbol: A0A8L2R9R3_RAT

Name: N/A

UniProtKB Accession Codes:

A0A8L2R9R3

Database IDs:

ARBA 5 CDD 1 CTD 1 Ensembl 2 GO 5 Gene3D 2 GeneTree 1 InterPro 6 NCBI Taxonomy 1 PANTHER 2 PIRSF 1 PIRSR 2 PRINTS 1 PROSITE 1 PeptideAtlas 1 Pfam 3 Proteomes 2 RGD 2 RefSeq 2 SMART 1 SUPFAM 2

Citations:

PubMed ID: 15057822

Title: Genome sequence of the Brown Norway rat yields insights into mammalian evolution.

PubMed ID: 15057822

DOI: 10.1038/nature02426

Sequence Information:

  • Length: 458
  • Mass: 52965
  • Checksum: B36C6B9FF62E9BFF
  • Sequence:
    • MDRWTLGGTS LTDLWRESHG QVCMTNCPTL IVMVGLPARG KTYISKKLTR YLNWIGVPTR 
EFNVGQYRRD MVKTYKSFEF FLPDNEEGLK IRKQCALAAL NDVRKFLSEE GGHVAVFDAT 
NTTRERRAMI FNFGEQNGYK TFFVESICVD PEVIAANIVQ VKLGSPDYVN RDSDEATEDF 
MRRIECYENS YESLDEEQDR DLSYIKIMDV GQSYVVNRVA DHIQSRIVYY LMNIHVTPRS 
IYLCRHGESE LNLKGRIGGD PGLSPRGREF SKHLAQFISD QNIKDLKVWT SQMKRTIQTA 
EALSVPYEQW KVLNEIDAGV CEEMTYEEIQ DHYPLEFALR DQDKYRYRYP KGESYEDLVQ 
RLEPVIMELE RQENVLVICH QAVMRCLLAY FLDKAAEELP YLKCPLHTVL KLTPVAYGCK 
VESIFLNVAA VNTHRDRPQN VDISRPSEEA LVTVPAHQ

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.