Sstr2 | ENSRNOG00000002793 | NCBI 54305

Details for: Sstr2

Gene ID: 54305

Symbol: Sstr2

Ensembl ID: ENSRNOG00000002793

Description: somatostatin receptor 2

Associated with

Class a/1 (rhodopsin-like receptors)
(R-RNO-373076)
G alpha (i) signalling events
(R-RNO-418594)
Gpcr downstream signalling
(R-RNO-388396)
Gpcr ligand binding
(R-RNO-500792)
Peptide ligand-binding receptors
(R-RNO-375276)
Signaling by gpcr
(R-RNO-372790)
Signal transduction
(R-RNO-162582)
Adenylate cyclase-inhibiting g protein-coupled receptor signaling pathway
(GO:0007193)
Cellular response to estradiol stimulus
(GO:0071392)
Cellular response to glucocorticoid stimulus
(GO:0071385)
Cerebellum development
(GO:0021549)
Cytosol
(GO:0005829)
Forebrain development
(GO:0030900)
G protein-coupled receptor heterodimeric complex
(GO:0038039)
G protein-coupled receptor signaling pathway
(GO:0007186)
Membrane
(GO:0016020)
Negative regulation of growth hormone secretion
(GO:0060125)
Neuron projection
(GO:0043005)
Neuropeptide binding
(GO:0042923)
Neuropeptide signaling pathway
(GO:0007218)
Pdz domain binding
(GO:0030165)
Peristalsis
(GO:0030432)
Plasma membrane
(GO:0005886)
Protein heterodimerization activity
(GO:0046982)
Response to starvation
(GO:0042594)
Somatostatin receptor activity
(GO:0004994)
Spermatogenesis
(GO:0007283)

Other Information

Proteins

Somatostatin receptor type 2

Genular Protein ID: 693142163

Symbol: SSR2_RAT

Name: Somatostatin receptor type 2

UniProtKB Accession Codes:

P30680

Database IDs:

Citations:

PubMed ID: 1374909

Title: Expression cloning of a rat brain somatostatin receptor cDNA.

PubMed ID: 1374909

DOI: 10.1073/pnas.89.10.4618

PubMed ID: 1348934

Title: Partial amino acid sequence of a somatostatin receptor isolated from GH4C1 pituitary cells.

PubMed ID: 1348934

DOI: 10.1016/0006-291x(92)91168-p

PubMed ID: 8386508

Title: Multiple gene transcripts of the somatostatin receptor SSTR2: tissue selective distribution and cAMP regulation.

PubMed ID: 8386508

DOI: 10.1006/bbrc.1993.1412

PubMed ID: 11134004

Title: Homo- and heterodimerization of somatostatin receptor subtypes. Inactivation of sst(3) receptor function by heterodimerization with sst(2A).

PubMed ID: 11134004

DOI: 10.1074/jbc.m006084200

PubMed ID: 17981995

Title: Distinct phosphorylation sites in the SST2A somatostatin receptor control internalization, desensitization, and arrestin binding.

PubMed ID: 17981995

DOI: 10.1124/mol.107.038570

PubMed ID: 19389921

Title: Site specificity of agonist and second messenger-activated kinases for somatostatin receptor subtype 2A (Sst2A) phosphorylation.

PubMed ID: 19389921

DOI: 10.1124/mol.108.054262

PubMed ID: 19434240

Title: The somatostatin 2A receptor is enriched in migrating neurons during rat and human brain development and stimulates migration and axonal outgrowth.

PubMed ID: 19434240

DOI: 10.1371/journal.pone.0005509

Sequence Information:

Length: 369
Mass: 41200
Checksum: 4990E489E88D7D19
Sequence:

MELTSEQFNG SQVWIPSPFD LNGSLGPSNG SNQTEPYYDM TSNAVLTFIY FVVCVVGLCG 
NTLVIYVILR YAKMKTITNI YILNLAIADE LFMLGLPFLA MQVALVHWPF GKAICRVVMT 
VDGINQFTSI FCLTVMSIDR YLAVVHPIKS AKWRRPRTAK MINVAVWGVS LLVILPIMIY 
AGLRSNQWGR SSCTINWPGE SGAWYTGFII YAFILGFLVP LTIICLCYLF IIIKVKSSGI 
RVGSSKRKKS EKKVTRMVSI VVAVFIFCWL PFYIFNVSSV SVAISPTPAL KGMFDFVVIL 
TYANSCANPI LYAFLSDNFK KSFQNVLCLV KVSGAEDGER SDSKQDKSRL NETTETQRTL 
LNGDLQTSI

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Sstr2

Associated with

Other Information

Expression cloning of a rat brain somatostatin receptor cDNA. PubMed ID: 1374909

Partial amino acid sequence of a somatostatin receptor isolated from GH4C1 pituitary cells. PubMed ID: 1348934

Multiple gene transcripts of the somatostatin receptor SSTR2: tissue selective distribution and cAMP regulation. PubMed ID: 8386508

Homo- and heterodimerization of somatostatin receptor subtypes. Inactivation of sst(3) receptor function by heterodimerization with sst(2A). PubMed ID: 11134004

Distinct phosphorylation sites in the SST2A somatostatin receptor control internalization, desensitization, and arrestin binding. PubMed ID: 17981995

Site specificity of agonist and second messenger-activated kinases for somatostatin receptor subtype 2A (Sst2A) phosphorylation. PubMed ID: 19389921

The somatostatin 2A receptor is enriched in migrating neurons during rat and human brain development and stimulates migration and axonal outgrowth. PubMed ID: 19434240