Ezr | ENSRNOG00000018524 | NCBI 54319

Details for: Ezr

Gene ID: 54319

Symbol: Ezr

Ensembl ID: ENSRNOG00000018524

Description: ezrin

Associated with

Axon guidance
(R-RNO-422475)
Developmental biology
(R-RNO-1266738)
L1cam interactions
(R-RNO-373760)
Nervous system development
(R-RNO-9675108)
Netrin-1 signaling
(R-RNO-373752)
Recycling pathway of l1
(R-RNO-437239)
Actin binding
(GO:0003779)
Actin cytoskeleton
(GO:0015629)
Actin cytoskeleton organization
(GO:0030036)
Actin filament
(GO:0005884)
Actin filament binding
(GO:0051015)
Actin filament bundle assembly
(GO:0051017)
Adherens junction
(GO:0005912)
Apical part of cell
(GO:0045177)
Apical plasma membrane
(GO:0016324)
Astral microtubule organization
(GO:0030953)
Astrocyte projection
(GO:0097449)
Atpase binding
(GO:0051117)
Basolateral plasma membrane
(GO:0016323)
Brush border
(GO:0005903)
Cell adhesion molecule binding
(GO:0050839)
Cell body
(GO:0044297)
Cell cortex
(GO:0005938)
Cell periphery
(GO:0071944)
Cell projection
(GO:0042995)
Cell tip
(GO:0051286)
Cellular response to camp
(GO:0071320)
Ciliary basal body
(GO:0036064)
Cortical microtubule organization
(GO:0043622)
Cytoplasm
(GO:0005737)
Cytoskeleton
(GO:0005856)
Cytosol
(GO:0005829)
Disordered domain specific binding
(GO:0097718)
Endosome
(GO:0005768)
Epithelial cell differentiation
(GO:0030855)
Establishment of centrosome localization
(GO:0051660)
Establishment of endothelial barrier
(GO:0061028)
Establishment of epithelial cell apical/basal polarity
(GO:0045198)
Establishment or maintenance of apical/basal cell polarity
(GO:0035088)
Fibrillar center
(GO:0001650)
Filopodium
(GO:0030175)
Filopodium assembly
(GO:0046847)
Focal adhesion
(GO:0005925)
Gland morphogenesis
(GO:0022612)
Identical protein binding
(GO:0042802)
Immunological synapse
(GO:0001772)
Intestinal d-glucose absorption
(GO:0001951)
Leukocyte cell-cell adhesion
(GO:0007159)
Membrane to membrane docking
(GO:0022614)
Microspike
(GO:0044393)
Microtubule binding
(GO:0008017)
Microvillus
(GO:0005902)
Microvillus assembly
(GO:0030033)
Microvillus membrane
(GO:0031528)
Negative regulation of erk1 and erk2 cascade
(GO:0070373)
Negative regulation of interleukin-2 production
(GO:0032703)
Negative regulation of p38mapk cascade
(GO:1903753)
Negative regulation of t cell receptor signaling pathway
(GO:0050860)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Perinuclear region of cytoplasm
(GO:0048471)
Plasma membrane
(GO:0005886)
Plasma membrane raft
(GO:0044853)
Positive regulation of early endosome to late endosome transport
(GO:2000643)
Positive regulation of gene expression
(GO:0010628)
Positive regulation of multicellular organism growth
(GO:0040018)
Positive regulation of protein catabolic process
(GO:0045732)
Positive regulation of protein localization to early endosome
(GO:1902966)
Positive regulation of protein localization to plasma membrane
(GO:1903078)
Postsynaptic actin cytoskeleton organization
(GO:0098974)
Protein-containing complex
(GO:0032991)
Protein-containing complex binding
(GO:0044877)
Protein-containing complex localization
(GO:0031503)
Protein binding
(GO:0005515)
Protein domain specific binding
(GO:0019904)
Protein kinase a binding
(GO:0051018)
Protein kinase a catalytic subunit binding
(GO:0034236)
Protein kinase a regulatory subunit binding
(GO:0034237)
Protein kinase a signaling
(GO:0010737)
Protein localization to cell cortex
(GO:0072697)
Protein localization to plasma membrane
(GO:0072659)
Receptor internalization
(GO:0031623)
Regulation of actin cytoskeleton organization
(GO:0032956)
Regulation of cell shape
(GO:0008360)
Regulation of cell size
(GO:0008361)
Regulation of microvillus length
(GO:0032532)
Regulation of non-canonical nf-kappab signal transduction
(GO:1901222)
Regulation of organelle assembly
(GO:1902115)
Ruffle
(GO:0001726)
Ruffle membrane
(GO:0032587)
S100 protein binding
(GO:0044548)
Sphingosine-1-phosphate receptor signaling pathway
(GO:0003376)
Structural molecule activity
(GO:0005198)
T-tubule
(GO:0030315)
Terminal web assembly
(GO:1902896)
Uropod
(GO:0001931)

Other Information

Proteins

Ezrin

Genular Protein ID: 1086100458

Symbol: EZRI_RAT

Name: Ezrin

UniProtKB Accession Codes:

P31977 Q5WQV4 Q66H97 Q8VHK3

Database IDs:

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 7640303

Title: Transcriptional regulation of the ezrin gene during rat intestinal development and epithelial differentiation.

PubMed ID: 7640303

DOI: 10.1016/0167-4781(95)00090-4

PubMed ID: 11457882

Title: Loss of glomerular foot processes is associated with uncoupling of podocalyxin from the actin cytoskeleton.

PubMed ID: 11457882

DOI: 10.1172/jci12539

PubMed ID: 15797715

Title: Characterization of the NF2 protein merlin and the ERM protein ezrin in human, rat, and mouse central nervous system.

PubMed ID: 15797715

DOI: 10.1016/j.mcn.2004.11.014

PubMed ID: 22673903

Title: Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.

PubMed ID: 22673903

DOI: 10.1038/ncomms1871

PubMed ID: 11163215

Title: Direct binding of the Na--H exchanger NHE1 to ERM proteins regulates the cortical cytoskeleton and cell shape independently of H(+) translocation.

PubMed ID: 11163215

DOI: 10.1016/s1097-2765(00)00139-8

Sequence Information:

Length: 586
Mass: 69391
Checksum: 3A5287052E74CCC9
Sequence:

MPKPINVRVT TMDAELEFAI QPNTTGKQLF DQVVKTIGLR EVWYFGLQYV DNKGFPTWLK 
LDKKVSAQEV RKENPVQFKF RAKFYPEDVA DELIQDITQK LFFLQVKEGI LSDEIYCPPE 
TAVLLGSYAV QAKFGDYNKE MHKSGYLSSE RLIPQRVMDQ HKLSRDQWED RIQVWHAEHR 
GMLKDSAMLE YLKIAQDLEM YGINYFEIKN KKGTDLWLGV DALGLNIYEK DDKLTPKIGF 
PWSEIRNISF NDKKFVIKPI DKKAPDFVFY APRLRINKRI LQLCMGNHEL YMRRRKPDTI 
EVQQMKAQAR EEKHQKQLER QQLETEKKRR ETVEREKEQM LREKEELMLR LQDFEQKTKR 
AEKELSEQIE KALQLEEERR RAQEEAERLE ADRMAALRAK EELERQAQDQ IKSQEQLAAE 
LAEYTAKIAL LEEARRRKED EVEEWQHRAK EAQDDLVKTK EELHLVMTAP PPPPPPVYEP 
VNYHVQEGLQ DEGAEPMGYS AELSSEGILD DRNEEKRITE AEKNERVQRQ LLTLSNELSQ 
ARDENKRTHN DIIHNENMRQ GRDKYKTLRQ IRQGNTKQRI DEFEAM

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Ezr

Associated with

Other Information

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Transcriptional regulation of the ezrin gene during rat intestinal development and epithelial differentiation. PubMed ID: 7640303

Loss of glomerular foot processes is associated with uncoupling of podocalyxin from the actin cytoskeleton. PubMed ID: 11457882

Characterization of the NF2 protein merlin and the ERM protein ezrin in human, rat, and mouse central nervous system. PubMed ID: 15797715

Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues. PubMed ID: 22673903