Arhgef5 | ENSMUSG00000033542 | NCBI 54324

Details for: Arhgef5

Gene ID: 54324

Symbol: Arhgef5

Ensembl ID: ENSMUSG00000033542

Description: Rho guanine nucleotide exchange factor 5

Associated with

Cdc42 gtpase cycle
(R-MMU-9013148)
Cell death signalling via nrage, nrif and nade
(R-MMU-204998)
Death receptor signaling
(R-MMU-73887)
G alpha (12/13) signalling events
(R-MMU-416482)
Gpcr downstream signalling
(R-MMU-388396)
Nrage signals death through jnk
(R-MMU-193648)
P75 ntr receptor-mediated signalling
(R-MMU-193704)
Rac1 gtpase cycle
(R-MMU-9013149)
Rhoa gtpase cycle
(R-MMU-8980692)
Rhob gtpase cycle
(R-MMU-9013026)
Rhoc gtpase cycle
(R-MMU-9013106)
Rhog gtpase cycle
(R-MMU-9013408)
Rho gtpase cycle
(R-MMU-9012999)
Signaling by gpcr
(R-MMU-372790)
Signaling by rho gtpases
(R-MMU-194315)
Signaling by rho gtpases, miro gtpases and rhobtb3
(R-MMU-9716542)
Signal transduction
(R-MMU-162582)
Actin cytoskeleton organization
(GO:0030036)
Activation of gtpase activity
(GO:0090630)
Anchoring junction
(GO:0070161)
Cell periphery
(GO:0071944)
Cell projection
(GO:0042995)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Guanyl-nucleotide exchange factor activity
(GO:0005085)
Hematopoietic stem cell homeostasis
(GO:0061484)
Intracellular signal transduction
(GO:0035556)
Lipid binding
(GO:0008289)
Myeloid dendritic cell chemotaxis
(GO:0002408)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Plasma membrane
(GO:0005886)
Positive regulation of dna-binding transcription factor activity
(GO:0051091)
Positive regulation of gtpase activity
(GO:0043547)
Positive regulation of jun kinase activity
(GO:0043507)
Positive regulation of podosome assembly
(GO:0071803)
Positive regulation of protein import
(GO:1904591)
Positive regulation of stress fiber assembly
(GO:0051496)
Protein binding
(GO:0005515)
Regulation of actin cytoskeleton organization
(GO:0032956)
Regulation of cytoskeleton organization
(GO:0051493)
Regulation of gtpase activity
(GO:0043087)

Other Information

Proteins

ARHG5_MOUSE

Genular Protein ID: 347388201

Symbol: ARHG5_MOUSE

Name: N/A

UniProtKB Accession Codes:

E9Q7D5 Q8R172 Q922T1

Database IDs:

Citations:

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 19713215

Title: Regulation of immature dendritic cell migration by RhoA guanine nucleotide exchange factor Arhgef5.

PubMed ID: 19713215

DOI: 10.1074/jbc.m109.047282

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 21525037

Title: The guanine nucleotide exchange factor Arhgef5 plays crucial roles in Src-induced podosome formation.

PubMed ID: 21525037

DOI: 10.1242/jcs.080291

Sequence Information:

Length: 1581
Mass: 176664
Checksum: CE61F8807C1C4102
Sequence:

MEAEEPEYGV STEVPDIEEL KTIPEGIMRS SQIPALDPEA QEDRDPSYKW TDGHRPVMNQ 
SKVLRDMGDH TPNSMAIFFK KESSDMETSQ EILLAEACNT PDQQEAVIQS LKDRLSRTIA 
APELLACAVQ EEWLDIPSKL DNRVGAELQS ELMSLTLAVS KEKEEEETSP DTSIPRGSWP 
PCKTHPGETE QTQGSGSELL RQGKQLQLEA TQENQGQEGF LQSQEAQGLE EQEGQEVEIQ 
EEGTLNEGIC FGGLLGEQEE VEEGFNGNEE EQKQGQIQSY MLLGGQWENE GLSGELEGLN 
YSERGQENRE RRVWVLRDSE EEGQDQESRE VEERRVATQY TENQRLVEKS EIVKRKQRDH 
DQTGKVMPVR DQKEVVDSGD RVQGNGDSGG QTAVEGSRPG EDSKPSLPVA SVDPEVLSPG 
TLFPGISSSV ADIPQIQKEP VCEELSPQAP ALEPTEWSHQ PISPPASFAP EESLDNRTHN 
SQQEEFRLRK GIEVVSASTS VAPSGTRDSP PFSPPNVFSS TATLSPVSSS VILPEETPTA 
SASADTPHHC GPCETPPLPA KSSRYPCATS DTANPHSPLS SYTGVTQHLR SNSFPGSHRT 
EQTPDSLGMS LSFSHLELPQ RPPKPAIYGS LTPRRNRRSR DGIVFSDSST ALFALKQDSE 
EFTSNPERPS SPHGSPTWGS PQNSAFAIGS PANVSSPPTV SMDMTIREAL LPIPPEKRHS 
YSHIVERDGL LHEVASTLKR HSHPPPLTLS SGLHRSSKGS FSLVPDSTVA RQHRPLPSTP 
ESPNHTQTSI PSRLRYNKPL PPTPDMPEFY HPSISSSYIS RMYRPLPPVP IIDPSSEPPP 
LPPKSRGRSK SIQGGVIHSG GQAKPRPNNQ DWTASTLSVG RTSWPPATGR STESLPLTSR 
CNNEVSPGLA FSNMTNLLSP SSPTTPWIPD LQRPTTKDES GLTEESEPPV RGSFRRSAPQ 
EEFNNTRRSA LGSRKNSEKP LHHQLEKASS WPHRRDPART SESSSEQVVL GQVPNKQKGW 
NRQGLRRPSI LPESSSDLRN PAAGRLPGSS DSVVFREKKP KEGMGGFSRR CSKLISSQLL 
YQEYSDVVLN KEIQSQQRLD SLAEPHGLSS PRHRRKALVS SDSYLQRLSM ASSGSLWQEI 
PVVRNSTVLL SMTHEDQKLQ EAKFELIVSE ASYLRSLNIA VDHFQHSAQL RGTLSNQDHQ 
WLFSRLQDVR DVSTTFLSDL EENFENNIFS FQVCDVVLNH AADFHRVYLP YVTNQTYQER 
TFQSLMNSNS SFREVLEKLE SDPICQRLSL KSFLILPFQR ITRLKLLLQN ILKRTQPGSS 
EEAEATKAHH ALEKLIRDCN SNVQRMRRTE ELIYLSQKIE FECKIFPLIS QSRWLVKSGE 
LTALEFSVSP GLRRKLTTRP VHLHLFNDCL LLSRPREGSR FLVFDHAPFS SIRGEKCEMK 
LHGPHKNLFR LFLLHNAQGT QVEFLFRTET QSEKLRWISA LAMPREELDL LECYDSPQVQ 
CLRAYKPREN DELALEKADV VMVTQQSSDG WLEGVRLSDG EQGWFPVQQV EFISNPEVRA 
QNLKEAHRVK TAKLQLVEQQ V

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Arhgef5

Associated with

Other Information

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Regulation of immature dendritic cell migration by RhoA guanine nucleotide exchange factor Arhgef5. PubMed ID: 19713215