SOX18 | ENSG00000203883 | NCBI 54345

Details for: SOX18

Gene ID: 54345

Symbol: SOX18

Ensembl ID: ENSG00000203883

Description: SRY-box transcription factor 18

Associated with

Angiogenesis
(GO:0001525)
Blood vessel endothelial cell migration
(GO:0043534)
Cell maturation
(GO:0048469)
Chromatin
(GO:0000785)
Dna-binding transcription activator activity, rna polymerase ii-specific
(GO:0001228)
Dna-binding transcription factor activity, rna polymerase ii-specific
(GO:0000981)
Embryonic heart tube development
(GO:0035050)
Endocardial cell differentiation
(GO:0060956)
Endocardium formation
(GO:0060214)
Establishment of endothelial barrier
(GO:0061028)
Hair cycle process
(GO:0022405)
Hair follicle development
(GO:0001942)
Heart looping
(GO:0001947)
In utero embryonic development
(GO:0001701)
Lymphangiogenesis
(GO:0001946)
Lymphatic endothelial cell differentiation
(GO:0060836)
Negative regulation of dna-templated transcription
(GO:0045892)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Nucleus
(GO:0005634)
Outflow tract morphogenesis
(GO:0003151)
Positive regulation of dna-templated transcription
(GO:0045893)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Regulation of stem cell proliferation
(GO:0072091)
Rna polymerase ii cis-regulatory region sequence-specific dna binding
(GO:0000978)
Sequence-specific double-stranded dna binding
(GO:1990837)
Stem cell fate specification
(GO:0048866)
Transcription cis-regulatory region binding
(GO:0000976)
Transcription regulator complex
(GO:0005667)
Vasculature development
(GO:0001944)
Vasculogenesis
(GO:0001570)

Other Information

Proteins

Transcription factor SOX-18

Genular Protein ID: 579492162

Symbol: SOX18_HUMAN

Name: Transcription factor SOX-18

UniProtKB Accession Codes:

P35713 Q0VGA9 Q9NPH8

Database IDs:

Citations:

PubMed ID: 10858556

Title: The human SOX18 gene: cDNA cloning and high resolution mapping.

PubMed ID: 10858556

DOI: 10.1016/s0167-4781(00)00078-6

PubMed ID: 10807548

Title: cDNA cloning, tissue expression, and chromosome mapping of human homolog of SOX18.

PubMed ID: 10807548

DOI: 10.1007/s100380050210

PubMed ID: 11130989

Title: Structure, mapping, and expression of human SOX18.

PubMed ID: 11130989

DOI: 10.1007/s003350010216

PubMed ID: 11780052

Title: The DNA sequence and comparative analysis of human chromosome 20.

PubMed ID: 11780052

DOI: 10.1038/414865a

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 1614875

Title: A conserved family of genes related to the testis determining gene, SRY.

PubMed ID: 1614875

DOI: 10.1093/nar/20.11.2887

PubMed ID: 17603017

Title: A novel 9-amino-acid transactivation domain in the C-terminal part of Sox18.

PubMed ID: 17603017

DOI: 10.1016/j.bbrc.2007.06.095

PubMed ID: 12740761

Title: Mutations in the transcription factor gene SOX18 underlie recessive and dominant forms of hypotrichosis-lymphedema-telangiectasia.

PubMed ID: 12740761

DOI: 10.1086/375614

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24697860

Title: Hypotrichosis-lymphedema-telangiectasia-renal defect associated with a truncating mutation in the SOX18 gene.

PubMed ID: 24697860

DOI: 10.1111/cge.12388

Sequence Information:

Length: 384
Mass: 40891
Checksum: 327462E519770062
Sequence:

MQRSPPGYGA QDDPPARRDC AWAPGHGAAA DTRGLAAGPA ALAAPAAPAS PPSPQRSPPR 
SPEPGRYGLS PAGRGERQAA DESRIRRPMN AFMVWAKDER KRLAQQNPDL HNAVLSKMLG 
KAWKELNAAE KRPFVEEAER LRVQHLRDHP NYKYRPRRKK QARKARRLEP GLLLPGLAPP 
QPPPEPFPAA SGSARAFREL PPLGAEFDGL GLPTPERSPL DGLEPGEAAF FPPPAAPEDC 
ALRPFRAPYA PTELSRDPGG CYGAPLAEAL RTAPPAAPLA GLYYGTLGTP GPYPGPLSPP 
PEAPPLESAE PLGPAADLWA DVDLTEFDQY LNCSRTRPDA PGLPYHVALA KLGPRAMSCP 
EESSLISALS DASSAVYYSA CISG

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: SOX18

Associated with

Other Information

The human SOX18 gene: cDNA cloning and high resolution mapping. PubMed ID: 10858556

cDNA cloning, tissue expression, and chromosome mapping of human homolog of SOX18. PubMed ID: 10807548

Structure, mapping, and expression of human SOX18. PubMed ID: 11130989

The DNA sequence and comparative analysis of human chromosome 20. PubMed ID: 11780052

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

A conserved family of genes related to the testis determining gene, SRY. PubMed ID: 1614875

A novel 9-amino-acid transactivation domain in the C-terminal part of Sox18. PubMed ID: 17603017

Mutations in the transcription factor gene SOX18 underlie recessive and dominant forms of hypotrichosis-lymphedema-telangiectasia. PubMed ID: 12740761

Toward a comprehensive characterization of a human cancer cell phosphoproteome. PubMed ID: 23186163

Hypotrichosis-lymphedema-telangiectasia-renal defect associated with a truncating mutation in the SOX18 gene. PubMed ID: 24697860