Details for: Skap2

Gene ID: 54353

Symbol: Skap2

Ensembl ID: ENSMUSG00000059182

Description: src family associated phosphoprotein 2

Associated with

Other Information

Genular Protein ID: 3660137977

Symbol: SKAP2_MOUSE

Name: Src kinase-associated phosphoprotein 2

UniProtKB Accession Codes:

Q3UND0 Q8BK74 Q9Z2K4

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CCDS 1 CDD 1 CORUM 1 CTD 1 ChiTaRS 1 DNASU 1 DisProt 1 EMBL 5 EPD 1 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 6 Gene3D 3 GeneTree 1 Genevisible 1 GlyGen 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MGI 1 MINT 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PDB 8 PDBsum 5 PRINTS 1 PRO 1 PROSITE 2 PROSITE-ProRule 2 PaxDb 1 PeptideAtlas 1 Pfam 2 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 RNAct 1 Reactome 1 RefSeq 1 SAM 1 SMART 2 SMR 1 STRING 1 SUPFAM 2 TreeFam 1 UCSC 2 UniProtKB 2 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1

Citations:

PubMed ID: 11063873

Title: Adaptor protein SKAP55R is associated with myeloid differentiation and growth arrest.

PubMed ID: 11063873

DOI: 10.1016/s0301-472x(00)00537-3

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9755858

Title: SKAP-HOM, a novel adaptor protein homologous to the FYN-associated protein SKAP55.

PubMed ID: 9755858

DOI: 10.1016/s0014-5793(98)01040-0

PubMed ID: 11207596

Title: The Yersinia tyrosine phosphatase YopH targets a novel adhesion-regulated signalling complex in macrophages.

PubMed ID: 11207596

DOI: 10.1046/j.1462-5822.2000.00061.x

PubMed ID: 10469599

Title: SHPS-1 is a scaffold for assembling distinct adhesion-regulated multi-protein complexes in macrophages.

PubMed ID: 10469599

DOI: 10.1016/s0960-9822(99)80401-1

PubMed ID: 12893833

Title: Identification and characterization of a novel Pyk2/related adhesion focal tyrosine kinase-associated protein that inhibits alpha-synuclein phosphorylation.

PubMed ID: 12893833

DOI: 10.1074/jbc.m213217200

PubMed ID: 15894167

Title: Macrophage colony-stimulating factor receptor induces tyrosine phosphorylation of SKAP55R adaptor and its association with actin.

PubMed ID: 15894167

DOI: 10.1016/j.cellsig.2004.11.009

PubMed ID: 16135797

Title: Regulation of in vitro and in vivo immune functions by the cytosolic adaptor protein SKAP-HOM.

PubMed ID: 16135797

DOI: 10.1128/mcb.25.18.8052-8063.2005

PubMed ID: 15592455

Title: Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.

PubMed ID: 15592455

DOI: 10.1038/nbt1046

PubMed ID: 17003372

Title: ADAP is required for normal alphaIIb-beta3 activation by VWF/GP Ib-IX-V and other agonists.

PubMed ID: 17003372

DOI: 10.1182/blood-2006-05-022301

PubMed ID: 17947660

Title: Quantitative time-resolved phosphoproteomic analysis of mast cell signaling.

PubMed ID: 17947660

DOI: 10.4049/jimmunol.179.9.5864

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 19026786

Title: The Skap-hom dimerization and PH domains comprise a 3'-phosphoinositide-gated molecular switch.

PubMed ID: 19026786

DOI: 10.1016/j.molcel.2008.09.022

Sequence Information:

  • Length: 358
  • Mass: 40712
  • Checksum: B66973A656E44E05
  • Sequence:
    • MPNPSCTSSP GPLPEEIRNL LADVETFVAD TLKGENLSKK AKEKRESLIK KIKDVKSVYL 
QEFQDKGDAE DGDEYDDPFA GPADTISLAS ERYDKDDDGP SDGNQFPPIA AQDLPFVIKA 
GYLEKRRKDH SFLGFEWQKR WCALSKTVFY YYGSDKDKQQ KGEFAIDGYD VRMNNTLRKD 
GKKDCCFEIC APDKRIYQFT AASPKDAEEW VQQLKFILQD LGSDVIPEDD EERGELYDDV 
DHPAAVSSPQ RSQPIDDEIY EELPEEEEDT ASVKMDEQGK GSRDSVHHTS GDKSTDYANF 
YQGLWDCTGA LSDELSFKRG DVIYILSKEY NRYGWWVGEM KGAIGLVPKA YLMEMYDI

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.