Gabbr1 | ENSMUSG00000024462 | NCBI 54393

Details for: Gabbr1

Gene ID: 54393

Symbol: Gabbr1

Ensembl ID: ENSMUSG00000024462

Description: gamma-aminobutyric acid type B receptor subunit 1

Associated with

Activation of gabab receptors
(R-MMU-991365)
Activation of g protein gated potassium channels
(R-MMU-1296041)
Class c/3 (metabotropic glutamate/pheromone receptors)
(R-MMU-420499)
Gaba b receptor activation
(R-MMU-977444)
Gaba receptor activation
(R-MMU-977443)
G alpha (i) signalling events
(R-MMU-418594)
Gpcr downstream signalling
(R-MMU-388396)
Gpcr ligand binding
(R-MMU-500792)
G protein gated potassium channels
(R-MMU-1296059)
Inhibition of voltage gated ca2+ channels via gbeta/gamma subunits
(R-MMU-997272)
Inwardly rectifying k+ channels
(R-MMU-1296065)
Neuronal system
(R-MMU-112316)
Neurotransmitter receptors and postsynaptic signal transmission
(R-MMU-112314)
Potassium channels
(R-MMU-1296071)
Signaling by gpcr
(R-MMU-372790)
Transmission across chemical synapses
(R-MMU-112315)
Adenylate cyclase-inhibiting g protein-coupled receptor signaling pathway
(GO:0007193)
Axolemma
(GO:0030673)
Cell projection
(GO:0042995)
Chemical synaptic transmission
(GO:0007268)
Chemical synaptic transmission, postsynaptic
(GO:0099565)
Cytoplasm
(GO:0005737)
Dendritic shaft
(GO:0043198)
Dendritic spine
(GO:0043197)
Endoplasmic reticulum membrane
(GO:0005789)
Extracellular matrix protein binding
(GO:1990430)
Extracellular space
(GO:0005615)
Gaba-ergic synapse
(GO:0098982)
Gaba receptor complex
(GO:1902710)
Gamma-aminobutyric acid signaling pathway
(GO:0007214)
Glutamatergic synapse
(GO:0098978)
G protein-coupled gaba receptor activity
(GO:0004965)
G protein-coupled gaba receptor complex
(GO:1902712)
G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential
(GO:0099579)
G protein-coupled neurotransmitter receptor activity involved in regulation of presynaptic membrane potential
(GO:0150047)
G protein-coupled receptor activity
(GO:0004930)
G protein-coupled receptor dimeric complex
(GO:0038037)
G protein-coupled receptor heterodimeric complex
(GO:0038039)
G protein-coupled receptor signaling pathway
(GO:0007186)
Membrane
(GO:0016020)
Mitochondrial membrane
(GO:0031966)
Negative regulation of cell population proliferation
(GO:0008285)
Negative regulation of dopamine secretion
(GO:0033602)
Negative regulation of epinephrine secretion
(GO:0032811)
Negative regulation of gamma-aminobutyric acid secretion
(GO:0014053)
Negative regulation of synaptic transmission
(GO:0050805)
Neuron-glial cell signaling
(GO:0150099)
Neuronal cell body
(GO:0043025)
Osteoblast differentiation
(GO:0001649)
Plasma membrane
(GO:0005886)
Positive regulation of glutamate secretion
(GO:0014049)
Positive regulation of growth hormone secretion
(GO:0060124)
Postsynaptic membrane
(GO:0045211)
Presynapse
(GO:0098793)
Presynaptic membrane
(GO:0042734)
Protein binding
(GO:0005515)
Protein heterodimerization activity
(GO:0046982)
Regulation of glutamate secretion
(GO:0014048)
Regulation of postsynaptic membrane potential
(GO:0060078)
Schaffer collateral - ca1 synapse
(GO:0098685)
Signal transduction
(GO:0007165)
Synapse
(GO:0045202)
Synaptic membrane
(GO:0097060)
Synaptic transmission, gabaergic
(GO:0051932)
Synaptic vesicle
(GO:0008021)

Other Information

Proteins

Gamma-aminobutyric acid type B receptor subunit 1

Genular Protein ID: 864328178

Symbol: GABR1_MOUSE

Name: Gamma-aminobutyric acid type B receptor subunit 1

UniProtKB Accession Codes:

Q9WV18 Q6PGJ2 Q9WU48 Q9WV15 Q9WV16 Q9WV17

Database IDs:

Citations:

PubMed ID: 10773016

Title: Coexpression of full-length gamma-aminobutyric acid(B) (GABA(B)) receptors with truncated receptors and metabotropic glutamate receptor 4 supports the GABA(B) heterodimer as the functional receptor.

PubMed ID: 10773016

PubMed ID: 11306808

Title: The murine GABA(B) receptor 1: cDNA cloning, tissue distribution, structure of the Gabbr1 gene, and mapping to chromosome 17.

PubMed ID: 11306808

DOI: 10.1159/000056880

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10075644

Title: Identification of a GABAB receptor subunit, gb2, required for functional GABAB receptor activity.

PubMed ID: 10075644

DOI: 10.1074/jbc.274.12.7607

PubMed ID: 9872744

Title: Role of heteromer formation in GABAB receptor function.

PubMed ID: 9872744

DOI: 10.1126/science.283.5398.74

PubMed ID: 14718537

Title: Marlin-1, a novel RNA-binding protein associates with GABA receptors.

PubMed ID: 14718537

DOI: 10.1074/jbc.m311737200

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 960
Mass: 108216
Checksum: E4B5A9401E23E8B4
Sequence:

MLLLLLVPLF LRPLGAGGAQ TPNVTSEGCQ IIHPPWEGGI RYRGLTRDQV KAINFLPVDY 
EIEYVCRGER EVVGPKVRKC LANGSWTDMD TPSRCVRICS KSYLTLENGK VFLTGGDLPA 
LDGARVDFRC DPDFHLVGSS RSICSQGQWS TPKPHCQVNR TPHSERRAVY IGALFPMSGG 
WPGGQACQPA VEMALEDVNS RRDILPDYEL KLIHHDSKCD PGQATKYLYE LLYNDPIKII 
LMPGCSSVST LVAEAARMWN LIVLSYGSSS PALSNRQRFP TFFRTHPSAT LHNPTRVKLF 
EKWGWKKIAT IQQTTEVFTS TLDDLEERVK EAGIEITFRQ SFFSDPAVPV KNLKRQDARI 
IVGLFYETEA RKVFCEVYKE RLFGKKYVWF LIGWYADNWF KTYDPSINCT VEEMTEAVEG 
HITTEIVMLN PANTRSISNM TSQEFVEKLT KRLKRHPEET GGFQEAPLAY DAIWALALAL 
NKTSGGGGRS GVRLEDFNYN NQTITDQIYR AMNSSSFEGV SGHVVFDASG SRMAWTLIEQ 
LQGGSYKKIG YYDSTKDDLS WSKTDKWIGG SPPADQTLVI KTFRFLSQKL FISVSVLSSL 
GIVLAVVCLS FNIYNSHVRY IQNSQPNLNN LTAVGCSLAL AAVFPLGLDG YHIGRSQFPF 
VCQARLWLLG LGFSLGYGSM FTKIWWVHTV FTKKEEKKEW RKTLEPWKLY ATVGLLVGMD 
ILTLAIWQIV DPLHRTIETF AKEEPKEDID VSILPQLEHC SSKKMNTWLG IFYGYKGLLL 
LLGIFLAYET KSVSTEKIND HRAVGMAIYN VAVLCLITAP VTMILSSQQD AAFAFASLAI 
VFSSYITLVV LFVPKMRRLI TRGEWQSEAQ DTMKTGSSTN NNEEEKSRLL EKENRELEKI 
IAEKEERVSE LRHQLQSRQQ IRSRRHPPTP PDPSGGLPRG PSEPPDRLSC DGSRVHLLYK

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Gabbr1

Associated with

Other Information

Coexpression of full-length gamma-aminobutyric acid(B) (GABA(B)) receptors with truncated receptors and metabotropic glutamate receptor 4 supports the GABA(B) heterodimer as the functional receptor. PubMed ID: 10773016

The murine GABA(B) receptor 1: cDNA cloning, tissue distribution, structure of the Gabbr1 gene, and mapping to chromosome 17. PubMed ID: 11306808

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Identification of a GABAB receptor subunit, gb2, required for functional GABAB receptor activity. PubMed ID: 10075644

Role of heteromer formation in GABAB receptor function. PubMed ID: 9872744

Marlin-1, a novel RNA-binding protein associates with GABA receptors. PubMed ID: 14718537

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079