Details for: Cldn8

Gene ID: 54420

Symbol: Cldn8

Ensembl ID: ENSMUSG00000050520

Description: claudin 8

Associated with

Other Information

Genular Protein ID: 1486424027

Symbol: CLD8_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q9Z260

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CCDS 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 2 Ensembl 1 ExpressionAtlas 1 GO 10 Gene3D 1 GeneTree 1 Genevisible 1 HOGENOM 1 InParanoid 1 InterPro 3 KEGG 1 MGI 2 MINT 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRINTS 2 PRO 1 PROSITE 1 PaxDb 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 RefSeq 1 SMR 1 STRING 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 9892664

Title: Claudin multigene family encoding four-transmembrane domain protein components of tight junction strands.

PubMed ID: 9892664

DOI: 10.1073/pnas.96.2.511

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10601346

Title: Direct binding of three tight junction-associated MAGUKs, ZO-1, ZO-2, and ZO-3, with the COOH termini of claudins.

PubMed ID: 10601346

DOI: 10.1083/jcb.147.6.1351

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 20921420

Title: Claudin-4 forms paracellular chloride channel in the kidney and requires claudin-8 for tight junction localization.

PubMed ID: 20921420

DOI: 10.1073/pnas.1009399107

PubMed ID: 25831548

Title: KLHL3 regulates paracellular chloride transport in the kidney by ubiquitination of claudin-8.

PubMed ID: 25831548

DOI: 10.1073/pnas.1421441112

Sequence Information:

  • Length: 225
  • Mass: 24947
  • Checksum: 12BB3C460F23D876
  • Sequence:
    • MATYALQMAA LVLGGVGMVG TVAVTIMPQW RVSAFIESNI VVFENRWEGL WMNCMRHANI 
RMQCKVYDSL LALSPDLQAS RGLMCAASVL AFLAFMTAIL GMKCTRCTGD DENVKSRILL 
TAGIIFFITG LVVLIPVSWV ANSIIRDFYN PLVDVALKRE LGEALYIGWT TALVLIAGGA 
LFCCVFCCTE RSNSYRYSVP SHRTTQRSFH AEKRSPSIYS KSQYV

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.