Details for: SSH1

Gene ID: 54434

Symbol: SSH1

Ensembl ID: ENSG00000084112

Description: slingshot protein phosphatase 1

Associated with

Other Information

Genular Protein ID: 2396204678

Symbol: SSH1_HUMAN

Name: SSH-like protein 1

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11832213

Title: Control of actin reorganization by Slingshot, a family of phosphatases that dephosphorylate ADF/cofilin.

PubMed ID: 11832213

DOI: 10.1016/s0092-8674(01)00638-9

PubMed ID: 10718198

Title: Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.

PubMed ID: 10718198

DOI: 10.1093/dnares/7.1.65

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 14531860

Title: Differential activities, subcellular distribution and tissue expression patterns of three members of Slingshot family phosphatases that dephosphorylate cofilin.

PubMed ID: 14531860

DOI: 10.1046/j.1365-2443.2003.00678.x

PubMed ID: 12807904

Title: Cell cycle-associated changes in Slingshot phosphatase activity and roles in cytokinesis in animal cells.

PubMed ID: 12807904

DOI: 10.1074/jbc.m305802200

PubMed ID: 12684437

Title: Control of growth cone motility and morphology by LIM kinase and Slingshot via phosphorylation and dephosphorylation of cofilin.

PubMed ID: 12684437

DOI: 10.1523/jneurosci.23-07-02527.2003

PubMed ID: 15056216

Title: Efficient Salmonella entry requires activity cycles of host ADF and cofilin.

PubMed ID: 15056216

DOI: 10.1111/j.1462-5822.2004.00375.x

PubMed ID: 14645219

Title: Phosphoinositide 3-kinase-mediated activation of cofilin phosphatase Slingshot and its role for insulin-induced membrane protrusion.

PubMed ID: 14645219

DOI: 10.1074/jbc.m312591200

PubMed ID: 15159416

Title: A pathway of neuregulin-induced activation of cofilin-phosphatase Slingshot and cofilin in lamellipodia.

PubMed ID: 15159416

DOI: 10.1083/jcb.200401136

PubMed ID: 15660133

Title: Interplay between components of a novel LIM kinase-slingshot phosphatase complex regulates cofilin.

PubMed ID: 15660133

DOI: 10.1038/sj.emboj.7600543

PubMed ID: 15671020

Title: Calcium signal-induced cofilin dephosphorylation is mediated by Slingshot via calcineurin.

PubMed ID: 15671020

DOI: 10.1074/jbc.m411494200

PubMed ID: 16230460

Title: Spatial and temporal regulation of cofilin activity by LIM kinase and Slingshot is critical for directional cell migration.

PubMed ID: 16230460

DOI: 10.1083/jcb.200504029

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 1049
  • Mass: 115511
  • Checksum: 0600B9690F0E6F9C
  • Sequence:
  • MALVTLQRSP TPSAASSSAS NSELEAGSEE DRKLNLSLSE SFFMVKGAAL FLQQGSSPQG 
    QRSLQHPHKH AGDLPQHLQV MINLLRCEDR IKLAVRLESA WADRVRYMVV VYSSGRQDTE 
    ENILLGVDFS SKESKSCTIG MVLRLWSDTK IHLDGDGGFS VSTAGRMHIF KPVSVQAMWS 
    ALQVLHKACE VARRHNYFPG GVALIWATYY ESCISSEQSC INEWNAMQDL ESTRPDSPAL 
    FVDKPTEGER TERLIKAKLR SIMMSQDLEN VTSKEIRNEL EKQMNCNLKE LKEFIDNEML 
    LILGQMDKPS LIFDHLYLGS EWNASNLEEL QGSGVDYILN VTREIDNFFP GLFAYHNIRV 
    YDEETTDLLA HWNEAYHFIN KAKRNHSKCL VHCKMGVSRS ASTVIAYAMK EFGWPLEKAY 
    NYVKQKRSIT RPNAGFMRQL SEYEGILDAS KQRHNKLWRQ QTDSSLQQPV DDPAGPGDFL 
    PETPDGTPES QLPFLDDAAQ PGLGPPLPCC FRRLSDPLLP SPEDETGSLV HLEDPEREAL 
    LEEAAPPAEV HRPARQPQQG SGLCEKDVKK KLEFGSPKGR SGSLLQVEET EREEGLGAGR 
    WGQLPTQLDQ NLLNSENLNN NSKRSCPNGM EDDAIFGILN KVKPSYKSCA DCMYPTASGA 
    PEASRERCED PNAPAICTQP AFLPHITSSP VAHLASRSRV PEKPASGPTE PPPFLPPAGS 
    RRADTSGPGA GAALEPPASL LEPSRETPKV LPKSLLLKNS HCDKNPPSTE VVIKEESSPK 
    KDMKPAKDLR LLFSNESEKP TTNSYLMQHQ ESIIQLQKAG LVRKHTKELE RLKSVPADPA 
    PPSRDGPASR LEASIPEESQ DPAALHELGP LVMPSQAGSD EKSEAAPASL EGGSLKSPPP 
    FFYRLDHTSS FSKDFLKTIC YTPTSSSMSS NLTRSSSSDS IHSVRGKPGL VKQRTQEIET 
    RLRLAGLTVS SPLKRSHSLA KLGSLTFSTE DLSSEADPST VADSQDTTLS ESSFLHEPQG 
    TPRDPAATSK PSGKPAPENL KSPSWMSKS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.