Details for: Unc93b1

Gene ID: 54445

Symbol: Unc93b1

Ensembl ID: ENSMUSG00000036908

Description: unc-93 homolog B1, TLR signaling regulator

Associated with

Other Information

Genular Protein ID: 2351332131

Symbol: UN93B_MOUSE

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9798653

Title: Expressed genes in interleukin-4 treated B cells identified by cDNA representational difference analysis.

PubMed ID: 9798653

DOI: 10.1016/s0161-5890(98)00031-5

PubMed ID: 16415873

Title: The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9.

PubMed ID: 16415873

DOI: 10.1038/ni1297

PubMed ID: 17452530

Title: The interaction between the ER membrane protein UNC93B and TLR3, 7, and 9 is crucial for TLR signaling.

PubMed ID: 17452530

DOI: 10.1083/jcb.200612056

PubMed ID: 18305481

Title: UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes.

PubMed ID: 18305481

DOI: 10.1038/nature06726

PubMed ID: 19451267

Title: Unc93B1 biases Toll-like receptor responses to nucleic acid in dendritic cells toward DNA- but against RNA-sensing.

PubMed ID: 19451267

DOI: 10.1084/jem.20082316

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 33432245

Title: Cryo-EM structures of Toll-like receptors in complex with UNC93B1.

PubMed ID: 33432245

DOI: 10.1038/s41594-020-00542-w

Sequence Information:

  • Length: 598
  • Mass: 66981
  • Checksum: E0E8AC1C3BBD9E10
  • Sequence:
  • MEVEPPLYPV AGAAGPQGDE DRHGVPDGPE APLDELVGAY PNYNEEEEER RYYRRKRLGV 
    VKNVLAASTG VTLTYGVYLG LLQMQLILHY DETYREVKYG NMGLPDIDSK MLMGINVTPI 
    AALLYTPVLI RFFGTKWMMF LAVGIYALFV STNYWERYYT LVPSAVALGM AIVPLWASMG 
    NYITRMSQKY YEYSHYKEQD EQGPQQRPPR GSHAPYLLVF QAIFYSFFHL SFACAQLPMI 
    YFLNNYLYDL NHTLINVQSC GTKSQGILNG FNKTVLRTLP RSKNLIVVES VLMAVAFLAM 
    LMVLGLCGAA YRPTEEIDLR SVGWGNIFQL PFKHVRDFRL RHLVPFFIYS GFEVLFACTG 
    FALGYGVCSM GLERLAYLLI AYSLGASASS VLGLLGLWLP RSVPLVAGAG LHLLLTLSLF 
    FWAPAPRVLQ HSWIFYFVAA LWGVGSALNK TGLSTLLGIL YEDKERQDFI FTIYHWWQAV 
    AIFVVYLGSS LPMKAKLAVL LVTLVAAAAS YLWMEQKLQQ GLVPRQPRIP KPQHKVRGYR 
    YLEEDNSDES DMEGEQGQGD CAEDEAPQAG PLGAEPAGPC RKPCPYEQAL GGDGPEEQ

Genular Protein ID: 2024917020

Symbol: E9PYK0_MOUSE

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

  • Length: 619
  • Mass: 69353
  • Checksum: 3E2E5986A634E853
  • Sequence:
  • MKEVPTSCWC PELQALDLDL VMEVEPPLYP VAGAAGPQGD EDRHGVPDGP EAPLDELVGA 
    YPNYNEEEEE RRYYRRKRLG VVKNVLAAST GVTLTYGVYL GLLQMQLILH YDETYREVKY 
    GNMGLPDIDS KMLMGINVTP IAALLYTPVL IRFFGTKWMM FLAVGIYALF VSTNYWERYY 
    TLVPSAVALG MAIVPLWASM GNYITRMSQK YYEYSHYKEQ DEQGPQQRPP RGSHAPYLLV 
    FQAIFYSFFH LSFACAQLPM IYFLNNYLYD LNHTLINVQS CGTKSQGILN GFNKTVLRTL 
    PRSKNLIVVE SVLMAVAFLA MLMVLGLCGA AYRPTEEIDL RSVGWGNIFQ LPFKHVRDFR 
    LRHLVPFFIY SGFEVLFACT GFALGYGVCS MGLERLAYLL IAYSLGASAS SVLGLLGLWL 
    PRSVPLVAGA GLHLLLTLSL FFWAPAPRVL QHSWIFYFVA ALWGVGSALN KTGLSTLLGI 
    LYEDKERQDF IFTIYHWWQA VAIFVVYLGS SLPMKAKLAV LLVTLVAAAA SYLWMEQKLQ 
    QGLVPRQPRI PKPQHKVRGY RYLEEDNSDE SDMEGEQGQG DCAEDEAPQA GPLGAEPAGP 
    CRKPCPYEQA LGGDGPEEQ

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.