Details for: Il36a

Gene ID: 54448

Symbol: Il36a

Ensembl ID: ENSMUSG00000026984

Description: interleukin 36A

Associated with

Other Information

Genular Protein ID: 1901939528

Symbol: IL36A_MOUSE

Name: Interleukin-36 alpha

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10744718

Title: Identification and initial characterization of four novel members of the interleukin-1 family.

PubMed ID: 10744718

DOI: 10.1074/jbc.275.14.10308

PubMed ID: 11466363

Title: Two novel IL-1 family members, IL-1 delta and IL-1 epsilon, function as an antagonist and agonist of NF-kappa B activation through the orphan IL-1 receptor-related protein 2.

PubMed ID: 11466363

DOI: 10.4049/jimmunol.167.3.1440

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 20101239

Title: Local overexpression of interleukin-1 family, member 6 relates to the development of tubulointerstitial lesions.

PubMed ID: 20101239

DOI: 10.1038/labinvest.2009.148

PubMed ID: 21860022

Title: IL-36R ligands are potent regulators of dendritic and T cells.

PubMed ID: 21860022

DOI: 10.1182/blood-2011-05-356873

PubMed ID: 21965679

Title: Interleukin-36 (IL-36) ligands require processing for full agonist (IL-36alpha, IL-36beta, and IL-36gamma) or antagonist (IL-36Ra) activity.

PubMed ID: 21965679

DOI: 10.1074/jbc.m111.267922

PubMed ID: 21881584

Title: Inter-regulation of Th17 cytokines and the IL-36 cytokines in vitro and in vivo: implications in psoriasis pathogenesis.

PubMed ID: 21881584

DOI: 10.1038/jid.2011.234

PubMed ID: 23029241

Title: IL-36alpha exerts pro-inflammatory effects in the lungs of mice.

PubMed ID: 23029241

DOI: 10.1371/journal.pone.0045784

PubMed ID: 24829417

Title: IL-36 promotes myeloid cell infiltration, activation, and inflammatory activity in skin.

PubMed ID: 24829417

DOI: 10.4049/jimmunol.1301481

Sequence Information:

  • Length: 160
  • Mass: 18015
  • Checksum: AA0434D68FF62F4A
  • Sequence:
  • MNKEKELRAA SPSLRHVQDL SSRVWILQNN ILTAVPRKEQ TVPVTITLLP CQYLDTLETN 
    RGDPTYMGVQ RPMSCLFCTK DGEQPVLQLG EGNIMEMYNK KEPVKASLFY HKKSGTTSTF 
    ESAAFPGWFI AVCSKGSCPL ILTQELGEIF ITDFEMIVVH

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.