Details for: Il36rn

Gene ID: 54450

Symbol: Il36rn

Ensembl ID: ENSMUSG00000026983

Description: interleukin 36 receptor antagonist

Associated with

Other Information

Genular Protein ID: 150597093

Symbol: I36RA_MOUSE

Name: Interleukin-36 receptor antagonist protein

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11093146

Title: A tissue specific IL-1 receptor antagonist homolog from the IL-1 cluster lacks IL-1, IL-1ra, IL-18 and IL-18 antagonist activities.

PubMed ID: 11093146

DOI: 10.1002/1521-4141(200011)30:11<3299::aid-immu3299>3.0.co;2-s

PubMed ID: 10744718

Title: Identification and initial characterization of four novel members of the interleukin-1 family.

PubMed ID: 10744718

DOI: 10.1074/jbc.275.14.10308

PubMed ID: 11466363

Title: Two novel IL-1 family members, IL-1 delta and IL-1 epsilon, function as an antagonist and agonist of NF-kappa B activation through the orphan IL-1 receptor-related protein 2.

PubMed ID: 11466363

DOI: 10.4049/jimmunol.167.3.1440

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 17908936

Title: Opposing activities of two novel members of the IL-1 ligand family regulate skin inflammation.

PubMed ID: 17908936

DOI: 10.1084/jem.20070157

PubMed ID: 18284608

Title: IL-1F5 mediates anti-inflammatory activity in the brain through induction of IL-4 following interaction with SIGIRR/TIR8.

PubMed ID: 18284608

DOI: 10.1111/j.1471-4159.2008.05304.x

PubMed ID: 21860022

Title: IL-36R ligands are potent regulators of dendritic and T cells.

PubMed ID: 21860022

DOI: 10.1182/blood-2011-05-356873

PubMed ID: 21965679

Title: Interleukin-36 (IL-36) ligands require processing for full agonist (IL-36alpha, IL-36beta, and IL-36gamma) or antagonist (IL-36Ra) activity.

PubMed ID: 21965679

DOI: 10.1074/jbc.m111.267922

PubMed ID: 12974628

Title: High-resolution structure of murine interleukin 1 homologue IL-1F5 reveals unique loop conformations for receptor binding specificity.

PubMed ID: 12974628

DOI: 10.1021/bi0341197

Sequence Information:

  • Length: 156
  • Mass: 17136
  • Checksum: A4D1EE2F93CF77A7
  • Sequence:
  • MMVLSGALCF RMKDSALKVL YLHNNQLLAG GLHAEKVIKG EEISVVPNRA LDASLSPVIL 
    GVQGGSQCLS CGTEKGPILK LEPVNIMELY LGAKESKSFT FYRRDMGLTS SFESAAYPGW 
    FLCTSPEADQ PVRLTQIPED PAWDAPITDF YFQQCD

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.