Dll4 | ENSMUSG00000027314 | NCBI 54485

Details for: Dll4

Gene ID: 54485

Symbol: Dll4

Ensembl ID: ENSMUSG00000027314

Description: delta like canonical Notch ligand 4

Associated with

Notch3 activation and transmission of signal to the nucleus
(R-MMU-9013507)
Signaling by notch
(R-MMU-157118)
Signaling by notch3
(R-MMU-9012852)
Signal transduction
(R-MMU-162582)
Angiogenesis
(GO:0001525)
Aortic valve morphogenesis
(GO:0003180)
Blood vessel lumenization
(GO:0072554)
Blood vessel remodeling
(GO:0001974)
Branching involved in blood vessel morphogenesis
(GO:0001569)
Calcium ion binding
(GO:0005509)
Cardiac atrium morphogenesis
(GO:0003209)
Cardiac ventricle morphogenesis
(GO:0003208)
Cell communication
(GO:0007154)
Cell differentiation
(GO:0030154)
Cellular response to fibroblast growth factor stimulus
(GO:0044344)
Cellular response to vascular endothelial growth factor stimulus
(GO:0035924)
Dorsal aorta morphogenesis
(GO:0035912)
Membrane
(GO:0016020)
Multicellular organism development
(GO:0007275)
Negative regulation of blood vessel endothelial cell migration
(GO:0043537)
Negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis
(GO:1903588)
Negative regulation of cell migration involved in sprouting angiogenesis
(GO:0090051)
Negative regulation of cell population proliferation
(GO:0008285)
Negative regulation of endothelial cell migration
(GO:0010596)
Negative regulation of gene expression
(GO:0010629)
Negative regulation of notch signaling pathway
(GO:0045746)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Nervous system development
(GO:0007399)
Notch binding
(GO:0005112)
Notch signaling pathway
(GO:0007219)
Pericardium morphogenesis
(GO:0003344)
Plasma membrane
(GO:0005886)
Positive regulation of gene expression
(GO:0010628)
Positive regulation of neural precursor cell proliferation
(GO:2000179)
Positive regulation of notch signaling pathway
(GO:0045747)
Protein binding
(GO:0005515)
Receptor ligand activity
(GO:0048018)
Regulation of neural retina development
(GO:0061074)
Regulation of neurogenesis
(GO:0050767)
Response to stimulus
(GO:0050896)
T cell differentiation
(GO:0030217)
Ventral spinal cord interneuron fate commitment
(GO:0060579)
Ventricular trabecula myocardium morphogenesis
(GO:0003222)
Visual perception
(GO:0007601)

Other Information

Proteins

Delta-like protein 4

Genular Protein ID: 3901444487

Symbol: DLL4_MOUSE

Name: Delta-like protein 4

UniProtKB Accession Codes:

Q9JI71 Q9DBU9 Q9JHZ7

Database IDs:

Citations:

PubMed ID: 10837024

Title: Dll4, a novel Notch ligand expressed in arterial endothelium.

PubMed ID: 10837024

PubMed ID: 11134954

Title: Molecular cloning of Delta-4, a new mouse and human Notch ligand.

PubMed ID: 11134954

DOI: 10.1093/oxfordjournals.jbchem.a002832

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 22323600

Title: Forkhead box N4 (Foxn4) activates Dll4-Notch signaling to suppress photoreceptor cell fates of early retinal progenitors.

PubMed ID: 22323600

DOI: 10.1073/pnas.1115767109

Sequence Information:

Length: 686
Mass: 74991
Checksum: E7DD4FC15C4AFFBA
Sequence:

MTPASRSACR WALLLLAVLW PQQRAAGSGI FQLRLQEFVN QRGMLANGQS CEPGCRTFFR 
ICLKHFQATF SEGPCTFGNV STPVLGTNSF VVRDKNSGSG RNPLQLPFNF TWPGTFSLNI 
QAWHTPGDDL RPETSPGNSL ISQIIIQGSL AVGKIWRTDE QNDTLTRLSY SYRVICSDNY 
YGESCSRLCK KRDDHFGHYE CQPDGSLSCL PGWTGKYCDQ PICLSGCHEQ NGYCSKPDEC 
ICRPGWQGRL CNECIPHNGC RHGTCSIPWQ CACDEGWGGL FCDQDLNYCT HHSPCKNGST 
CSNSGPKGYT CTCLPGYTGE HCELGLSKCA SNPCRNGGSC KDQENSYHCL CPPGYYGQHC 
EHSTLTCADS PCFNGGSCRE RNQGSSYACE CPPNFTGSNC EKKVDRCTSN PCANGGQCQN 
RGPSRTCRCR PGFTGTHCEL HISDCARSPC AHGGTCHDLE NGPVCTCPAG FSGRRCEVRI 
THDACASGPC FNGATCYTGL SPNNFVCNCP YGFVGSRCEF PVGLPPSFPW VAVSLGVGLV 
VLLVLLVMVV VAVRQLRLRR PDDESREAMN NLSDFQKDNL IPAAQLKNTN QKKELEVDCG 
LDKSNCGKLQ NHTLDYNLAP GLLGRGGMPG KYPHSDKSLG EKVPLRLHSE KPECRISAIC 
SPRDSMYQSV CLISEERNEC VIATEV

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Dll4

Associated with

Other Information

Dll4, a novel Notch ligand expressed in arterial endothelium. PubMed ID: 10837024

Molecular cloning of Delta-4, a new mouse and human Notch ligand. PubMed ID: 11134954

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334