SMOX | ENSG00000088826 | NCBI 54498

Details for: SMOX

Gene ID: 54498

Symbol: SMOX

Ensembl ID: ENSG00000088826

Description: spermine oxidase

Associated with

Amine oxidase reactions
(R-HSA-140179)
Biological oxidations
(R-HSA-211859)
Interconversion of polyamines
(R-HSA-351200)
Metabolism
(R-HSA-1430728)
Metabolism of amino acids and derivatives
(R-HSA-71291)
Metabolism of polyamines
(R-HSA-351202)
Paos oxidise polyamines to amines
(R-HSA-141334)
Phase i - functionalization of compounds
(R-HSA-211945)
Cytosol
(GO:0005829)
Intracellular membrane-bounded organelle
(GO:0043231)
N1-acetylspermine:oxygen oxidoreductase (n1-acetylspermidine-forming) activity
(GO:0052895)
Norspermine:oxygen oxidoreductase activity
(GO:0052894)
Nuclear membrane
(GO:0031965)
Nucleoplasm
(GO:0005654)
Polyamine biosynthetic process
(GO:0006596)
Polyamine catabolic process
(GO:0006598)
Polyamine oxidase activity
(GO:0046592)
Spermine:oxygen oxidoreductase (spermidine-forming) activity
(GO:0052901)
Spermine catabolic process
(GO:0046208)
Xenobiotic metabolic process
(GO:0006805)

Other Information

Proteins

Spermine oxidase

Genular Protein ID: 38296162

Symbol: SMOX_HUMAN

Name: Spermine oxidase

UniProtKB Accession Codes:

Q9NWM0 A2A2P5 A2A2P6 A8BE87 D3DVZ4 Q5TE26 Q5TE27 Q6UY28 Q8IX00 Q96LC3 Q96LC4 Q96QT3 Q9BW38 Q9H6H1 Q9NP51 Q9NPY1 Q9NPY2

Database IDs:

Citations:

PubMed ID: 11454677

Title: Cloning and characterization of a human polyamine oxidase that is inducible by polyamine analogue exposure.

PubMed ID: 11454677

PubMed ID: 12398765

Title: Cloning and characterization of multiple human polyamine oxidase splice variants that code for isoenzymes with different biochemical characteristics.

PubMed ID: 12398765

DOI: 10.1042/bj20021587

PubMed ID: 18422650

Title: Nuclear localization of human spermine oxidase isoforms - possible implications in drug response and disease etiology.

PubMed ID: 18422650

DOI: 10.1111/j.1742-4658.2008.06419.x

PubMed ID: 12975309

Title: The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.

PubMed ID: 12975309

DOI: 10.1101/gr.1293003

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 11780052

Title: The DNA sequence and comparative analysis of human chromosome 20.

PubMed ID: 11780052

DOI: 10.1038/414865a

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 12727196

Title: Properties of purified recombinant human polyamine oxidase, PAOh1/SMO.

PubMed ID: 12727196

DOI: 10.1016/s0006-291x(03)00636-3

PubMed ID: 12141946

Title: Identification and characterization of a novel flavin-containing spermine oxidase of mammalian cell origin.

PubMed ID: 12141946

DOI: 10.1042/bj20020720

PubMed ID: 15221502

Title: Catabolism of polyamines.

PubMed ID: 15221502

DOI: 10.1007/s00726-004-0070-z

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

Sequence Information:

Length: 555
Mass: 61819
Checksum: BDBEA65ECE9F45BF
Sequence:

MQSCESSGDS ADDPLSRGLR RRGQPRVVVI GAGLAGLAAA KALLEQGFTD VTVLEASSHI 
GGRVQSVKLG HATFELGATW IHGSHGNPIY HLAEANGLLE ETTDGERSVG RISLYSKNGV 
ACYLTNHGRR IPKDVVEEFS DLYNEVYNLT QEFFRHDKPV NAESQNSVGV FTREEVRNRI 
RNDPDDPEAT KRLKLAMIQQ YLKVESCESS SHSMDEVSLS AFGEWTEIPG AHHIIPSGFM 
RVVELLAEGI PAHVIQLGKP VRCIHWDQAS ARPRGPEIEP RGEGDHNHDT GEGGQGGEEP 
RGGRWDEDEQ WSVVVECEDC ELIPADHVIV TVSLGVLKRQ YTSFFRPGLP TEKVAAIHRL 
GIGTTDKIFL EFEEPFWGPE CNSLQFVWED EAESHTLTYP PELWYRKICG FDVLYPPERY 
GHVLSGWICG EEALVMEKCD DEAVAEICTE MLRQFTGNPN IPKPRRILRS AWGSNPYFRG 
SYSYTQVGSS GADVEKLAKP LPYTESSKTA PMQVLFSGEA THRKYYSTTH GALLSGQREA 
ARLIEMYRDL FQQGT

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: SMOX

Associated with

Other Information

Cloning and characterization of a human polyamine oxidase that is inducible by polyamine analogue exposure. PubMed ID: 11454677

Cloning and characterization of multiple human polyamine oxidase splice variants that code for isoenzymes with different biochemical characteristics. PubMed ID: 12398765

Nuclear localization of human spermine oxidase isoforms - possible implications in drug response and disease etiology. PubMed ID: 18422650

The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. PubMed ID: 12975309

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

The DNA sequence and comparative analysis of human chromosome 20. PubMed ID: 11780052

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

The full-ORF clone resource of the German cDNA consortium. PubMed ID: 17974005

Properties of purified recombinant human polyamine oxidase, PAOh1/SMO. PubMed ID: 12727196

Identification and characterization of a novel flavin-containing spermine oxidase of mammalian cell origin. PubMed ID: 12141946

Catabolism of polyamines. PubMed ID: 15221502

The consensus coding sequences of human breast and colorectal cancers. PubMed ID: 16959974