DDX4 | ENSG00000152670 | NCBI 54514

Details for: DDX4

Gene ID: 54514

Symbol: DDX4

Ensembl ID: ENSG00000152670

Description: DEAD-box helicase 4

Associated with

Gene expression (transcription)
(R-HSA-74160)
Gene silencing by rna
(R-HSA-211000)
Piwi-interacting rna (pirna) biogenesis
(R-HSA-5601884)
Rho gtpase cycle
(R-HSA-9012999)
Rnd3 gtpase cycle
(R-HSA-9696264)
Signaling by rho gtpases
(R-HSA-194315)
Signaling by rho gtpases, miro gtpases and rhobtb3
(R-HSA-9716542)
Signal transduction
(R-HSA-162582)
Atp binding
(GO:0005524)
Atp hydrolysis activity
(GO:0016887)
Cell differentiation
(GO:0030154)
Cytoplasm
(GO:0005737)
Flagellated sperm motility
(GO:0030317)
Gamete generation
(GO:0007276)
Germ cell development
(GO:0007281)
Male meiosis i
(GO:0007141)
Male meiotic nuclear division
(GO:0007140)
Molecular condensate scaffold activity
(GO:0140693)
Mrna binding
(GO:0003729)
Nucleus
(GO:0005634)
Perinuclear region of cytoplasm
(GO:0048471)
P granule
(GO:0043186)
Pi-body
(GO:0071546)
Pip-body
(GO:0071547)
Pirna-mediated retrotransposon silencing by heterochromatin formation
(GO:0141006)
Pirna processing
(GO:0034587)
Rna helicase activity
(GO:0003724)
Sirna-mediated retrotransposon silencing by heterochromatin formation
(GO:0141007)
Spermatogenesis
(GO:0007283)

Other Information

Proteins

Probable ATP-dependent RNA helicase DDX4

Genular Protein ID: 3364840916

Symbol: DDX4_HUMAN

Name: Probable ATP-dependent RNA helicase DDX4

UniProtKB Accession Codes:

Q9NQI0 A8K8Q2 B3KSF4 D6RDK4 E9PCD8 Q5M7Z3 Q86VX0 Q9NT92 Q9NYB1

Database IDs:

Citations:

PubMed ID: 10920202

Title: The human VASA gene is specifically expressed in the germ cell lineage.

PubMed ID: 10920202

DOI: 10.1073/pnas.160274797

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15372022

Title: The DNA sequence and comparative analysis of human chromosome 5.

PubMed ID: 15372022

DOI: 10.1038/nature02919

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 21034600

Title: Spermatozoal protein profiles in male infertility with asthenozoospermia.

PubMed ID: 21034600

PubMed ID: 21421998

Title: NANOS3 function in human germ cell development.

PubMed ID: 21421998

DOI: 10.1093/hmg/ddr114

PubMed ID: 27622290

Title: Structural Basis for the Interaction between the IUS-SPRY Domain of RanBPM and DDX-4 in Germ Cell Development.

PubMed ID: 27622290

DOI: 10.1016/j.jmb.2016.09.004

Sequence Information:

Length: 724
Mass: 79308
Checksum: 6D313DD98B177067
Sequence:

MGDEDWEAEI NPHMSSYVPI FEKDRYSGEN GDNFNRTPAS SSEMDDGPSR RDHFMKSGFA 
SGRNFGNRDA GECNKRDNTS TMGGFGVGKS FGNRGFSNSR FEDGDSSGFW RESSNDCEDN 
PTRNRGFSKR GGYRDGNNSE ASGPYRRGGR GSFRGCRGGF GLGSPNNDLD PDECMQRTGG 
LFGSRRPVLS GTGNGDTSQS RSGSGSERGG YKGLNEEVIT GSGKNSWKSE AEGGESSDTQ 
GPKVTYIPPP PPEDEDSIFA HYQTGINFDK YDTILVEVSG HDAPPAILTF EEANLCQTLN 
NNIAKAGYTK LTPVQKYSIP IILAGRDLMA CAQTGSGKTA AFLLPILAHM MHDGITASRF 
KELQEPECII VAPTRELVNQ IYLEARKFSF GTCVRAVVIY GGTQLGHSIR QIVQGCNILC 
ATPGRLMDII GKEKIGLKQI KYLVLDEADR MLDMGFGPEM KKLISCPGMP SKEQRQTLMF 
SATFPEEIQR LAAEFLKSNY LFVAVGQVGG ACRDVQQTVL QVGQFSKREK LVEILRNIGD 
ERTMVFVETK KKADFIATFL CQEKISTTSI HGDREQRERE QALGDFRFGK CPVLVATSVA 
ARGLDIENVQ HVINFDLPST IDEYVHRIGR TGRCGNTGRA ISFFDLESDN HLAQPLVKVL 
TDAQQDVPAW LEEIAFSTYI PGFSGSTRGN VFASVDTRKG KSTLNTAGFS SSQAPNPVDD 
ESWD

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: DDX4

Associated with

Other Information

The human VASA gene is specifically expressed in the germ cell lineage. PubMed ID: 10920202

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

The DNA sequence and comparative analysis of human chromosome 5. PubMed ID: 15372022

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

The full-ORF clone resource of the German cDNA consortium. PubMed ID: 17974005

Lysine acetylation targets protein complexes and co-regulates major cellular functions. PubMed ID: 19608861

Spermatozoal protein profiles in male infertility with asthenozoospermia. PubMed ID: 21034600

NANOS3 function in human germ cell development. PubMed ID: 21421998

Structural Basis for the Interaction between the IUS-SPRY Domain of RanBPM and DDX-4 in Germ Cell Development. PubMed ID: 27622290