APBB1IP | ENSG00000077420 | NCBI 54518

Details for: APBB1IP

Gene ID: 54518

Symbol: APBB1IP

Ensembl ID: ENSG00000077420

Description: amyloid beta precursor protein binding family B member 1 interacting protein

Associated with

Disease
(R-HSA-1643685)
Diseases of signal transduction by growth factor receptors and second messengers
(R-HSA-5663202)
Grb2:sos provides linkage to mapk signaling for integrins
(R-HSA-354194)
Hemostasis
(R-HSA-109582)
Integrin signaling
(R-HSA-354192)
Map2k and mapk activation
(R-HSA-5674135)
Mapk1/mapk3 signaling
(R-HSA-5684996)
Mapk family signaling cascades
(R-HSA-5683057)
Oncogenic mapk signaling
(R-HSA-6802957)
P130cas linkage to mapk signaling for integrins
(R-HSA-372708)
Paradoxical activation of raf signaling by kinase inactive braf
(R-HSA-6802955)
Platelet activation, signaling and aggregation
(R-HSA-76002)
Platelet aggregation (plug formation)
(R-HSA-76009)
Raf/map kinase cascade
(R-HSA-5673001)
Signaling by braf and raf1 fusions
(R-HSA-6802952)
Signaling by high-kinase activity braf mutants
(R-HSA-6802948)
Signaling by moderate kinase activity braf mutants
(R-HSA-6802946)
Signaling by raf1 mutants
(R-HSA-9656223)
Signaling by ras mutants
(R-HSA-6802949)
Signaling downstream of ras mutants
(R-HSA-9649948)
Cytoskeleton
(GO:0005856)
Cytosol
(GO:0005829)
Focal adhesion
(GO:0005925)
Lamellipodium
(GO:0030027)
Plasma membrane
(GO:0005886)
Positive regulation of cell adhesion
(GO:0045785)
Protein binding
(GO:0005515)
Signal transduction
(GO:0007165)
T cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell
(GO:0002291)
T cell receptor complex
(GO:0042101)

Other Information

Proteins

Amyloid beta A4 precursor protein-binding family B member 1-interacting protein

Genular Protein ID: 335478152

Symbol: AB1IP_HUMAN

Name: Amyloid beta A4 precursor protein-binding family B member 1-interacting protein

UniProtKB Accession Codes:

Q7Z5R6 Q8IWS8 Q8IYL7 Q8IZZ7

Database IDs:

Citations:

PubMed ID: 14530287

Title: The retinoic acid-responsive proline-rich protein is identified in promyeloleukemic HL-60 cells.

PubMed ID: 14530287

DOI: 10.1074/jbc.m308016200

PubMed ID: 15469846

Title: RIAM, an Ena/VASP and profilin ligand, interacts with Rap1-GTP and mediates Rap1-induced adhesion.

PubMed ID: 15469846

DOI: 10.1016/j.devcel.2004.07.021

PubMed ID: 15642358

Title: PREL1 provides a link from Ras signalling to the actin cytoskeleton via Ena/VASP proteins.

PubMed ID: 15642358

DOI: 10.1016/j.febslet.2004.10.110

PubMed ID: 15164054

Title: The DNA sequence and comparative analysis of human chromosome 10.

PubMed ID: 15164054

DOI: 10.1038/nature02462

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 19367720

Title: Phosphorylation analysis of primary human T lymphocytes using sequential IMAC and titanium oxide enrichment.

PubMed ID: 19367720

DOI: 10.1021/pr800500r

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 23389036

Title: RIAM and vinculin binding to talin are mutually exclusive and regulate adhesion assembly and turnover.

PubMed ID: 23389036

DOI: 10.1074/jbc.m112.438119

Sequence Information:

Length: 666
Mass: 73183
Checksum: 525C906C490D8D97
Sequence:

MGESSEDIDQ MFSTLLGEMD LLTQSLGVDT LPPPDPNPPR AEFNYSVGFK DLNESLNALE 
DQDLDALMAD LVADISEAEQ RTIQAQKESL QNQHHSASLQ ASIFSGAASL GYGTNVAATG 
ISQYEDDLPP PPADPVLDLP LPPPPPEPLS QEEEEAQAKA DKIKLALEKL KEAKVKKLVV 
KVHMNDNSTK SLMVDERQLA RDVLDNLFEK THCDCNVDWC LYEIYPELQI ERFFEDHENV 
VEVLSDWTRD TENKILFLEK EEKYAVFKNP QNFYLDNRGK KESKETNEKM NAKNKESLLE 
ESFCGTSIIV PELEGALYLK EDGKKSWKRR YFLLRASGIY YVPKGKTKTS RDLACFIQFE 
NVNIYYGTQH KMKYKAPTDY CFVLKHPQIQ KESQYIKYLC CDDTRTLNQW VMGIRIAKYG 
KTLYDNYQRA VAKAGLASRW TNLGTVNAAA PAQPSTGPKT GTTQPNGQIP QATHSVSAVL 
QEAQRHAETS KDKKPALGNH HDPAVPRAPH APKSSLPPPP PVRRSSDTSG SPATPLKAKG 
TGGGGLPAPP DDFLPPPPPP PPLDDPELPP PPPDFMEPPP DFVPPPPPSY AGIAGSELPP 
PPPPPPAPAP APVPDSARPP PAVAKRPPVP PKRQENPGHP GGAGGGEQDF MSDLMKALQK 
KRGNVS

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: APBB1IP

Associated with

Other Information

The retinoic acid-responsive proline-rich protein is identified in promyeloleukemic HL-60 cells. PubMed ID: 14530287

RIAM, an Ena/VASP and profilin ligand, interacts with Rap1-GTP and mediates Rap1-induced adhesion. PubMed ID: 15469846

PREL1 provides a link from Ras signalling to the actin cytoskeleton via Ena/VASP proteins. PubMed ID: 15642358

The DNA sequence and comparative analysis of human chromosome 10. PubMed ID: 15164054

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Phosphorylation analysis of primary human T lymphocytes using sequential IMAC and titanium oxide enrichment. PubMed ID: 19367720

Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. PubMed ID: 19690332

Initial characterization of the human central proteome. PubMed ID: 21269460

An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. PubMed ID: 24275569

RIAM and vinculin binding to talin are mutually exclusive and regulate adhesion assembly and turnover. PubMed ID: 23389036