Details for: Syt7

Gene ID: 54525

Symbol: Syt7

Ensembl ID: ENSMUSG00000024743

Description: synaptotagmin VII

Associated with

Other Information

Genular Protein ID: 1963800714

Symbol: SYT7_MOUSE

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10531343

Title: Conserved N-terminal cysteine motif is essential for homo- and heterodimer formation of synaptotagmins III, V, VI, and X.

PubMed ID: 10531343

DOI: 10.1074/jbc.274.44.31421

PubMed ID: 12071850

Title: Alternative splicing isoforms of synaptotagmin VII in the mouse, rat and human.

PubMed ID: 12071850

DOI: 10.1042/bj20011877

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10871604

Title: Distinct self-oligomerization activities of synaptotagmin family. Unique calcium-dependent oligomerization properties of synaptotagmin VII.

PubMed ID: 10871604

DOI: 10.1074/jbc.m001376200

PubMed ID: 11395007

Title: Synaptotagmin VII as a plasma membrane Ca(2+) sensor in exocytosis.

PubMed ID: 11395007

DOI: 10.1016/s0896-6273(01)00290-2

PubMed ID: 12925704

Title: Impaired membrane resealing and autoimmune myositis in synaptotagmin VII-deficient mice.

PubMed ID: 12925704

DOI: 10.1083/jcb.200305131

PubMed ID: 16982801

Title: Ca2+ and synaptotagmin VII-dependent delivery of lysosomal membrane to nascent phagosomes.

PubMed ID: 16982801

DOI: 10.1083/jcb.200605004

PubMed ID: 17720139

Title: Regulation of insulin secretion and GLUT4 trafficking by the calcium sensor synaptotagmin VII.

PubMed ID: 17720139

DOI: 10.1016/j.bbrc.2007.08.023

PubMed ID: 18539119

Title: Synaptotagmin VII regulates bone remodeling by modulating osteoclast and osteoblast secretion.

PubMed ID: 18539119

DOI: 10.1016/j.devcel.2008.03.022

PubMed ID: 18308938

Title: Impaired insulin secretion and glucose intolerance in synaptotagmin-7 null mutant mice.

PubMed ID: 18308938

DOI: 10.1073/pnas.0711700105

PubMed ID: 19171650

Title: Synaptotagmin-7 is a principal Ca2+ sensor for Ca2+ -induced glucagon exocytosis in pancreas.

PubMed ID: 19171650

DOI: 10.1113/jphysiol.2008.168005

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 21041449

Title: Palmitoylation-dependent association with CD63 targets the Ca2+ sensor synaptotagmin VII to lysosomes.

PubMed ID: 21041449

DOI: 10.1083/jcb.201003021

PubMed ID: 20956309

Title: Push-and-pull regulation of the fusion pore by synaptotagmin-7.

PubMed ID: 20956309

DOI: 10.1073/pnas.1014070107

PubMed ID: 24569478

Title: Synaptotagmin 7 functions as a Ca2+-sensor for synaptic vesicle replenishment.

PubMed ID: 24569478

DOI: 10.7554/elife.01524

PubMed ID: 24129315

Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.

PubMed ID: 24129315

DOI: 10.1074/mcp.o113.027870

PubMed ID: 25860611

Title: Cholesterol transport through lysosome-peroxisome membrane contacts.

PubMed ID: 25860611

DOI: 10.1016/j.cell.2015.02.019

PubMed ID: 26738595

Title: The calcium sensor synaptotagmin 7 is required for synaptic facilitation.

PubMed ID: 26738595

DOI: 10.1038/nature16507

PubMed ID: 30429473

Title: Presenilin-mediated cleavage of APP regulates synaptotagmin-7 and presynaptic plasticity.

PubMed ID: 30429473

DOI: 10.1038/s41467-018-06813-x

PubMed ID: 20824061

Title: Structural and mutational analysis of functional differentiation between synaptotagmins-1 and -7.

PubMed ID: 20824061

DOI: 10.1371/journal.pone.0012544

Sequence Information:

  • Length: 403
  • Mass: 45472
  • Checksum: 4E63C5779C2ED43E
  • Sequence:
  • MYRDPEAASP GAPTRDVLLV SAIITVSLSV TIVLCGLCHW CQRKLGKRYK NSLETVGTPD 
    SGRGRGEKKA IKLPAGGKAV NTAPVPGQTP HDESDRRTET RSSVSDLVNS LTSEMLMLSP 
    GSEEDEAHEG CSRENLGRIQ FSVGYNFQES TLTVKVMKAQ ELPAKDFSGT SDPFVKIYLL 
    PDKKHKLETK VKRKNLNPHW NETFLFEGFP YEKVVQRVLY LQVLDYDRFS RNDPIGEVSI 
    PLNKVDLTQM QTFWKDLKPC SDGSGSRGEL LLSLCYNPSA NSIIVNIIKA RNLKAMDIGG 
    TSDPYVKVWL MYKDKRVEKK KTVTKKRNLN PIFNESFAFD IPTEKLRETT IIITVMDKDK 
    LSRNDVIGKI YLSWKSGPGE VKHWKDMIAR PRQPVAQWHQ LKA

Genular Protein ID: 1267241852

Symbol: A0A498WGM0_MOUSE

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

Sequence Information:

  • Length: 687
  • Mass: 75778
  • Checksum: 20B5F34AA9845039
  • Sequence:
  • MYRDPEAASP GAPTRDVLLV SAIITVSLSV TIVLCGLCHW CQRKLGKRYK NSLETVGTPD 
    SGRGRGEKKA INDLDRDFWN NNESTVQQKW SSYPPKEFIL NISPYAPYGD PRLSLNGTLL 
    SGAKVATAAA GLAVEREGRL GEKPAPVPPP GEDALRSGGA APSEPGSSGK AGRGRWRMVQ 
    SHLAAGKLNL SNFEDSTLST ATTLESIPSS AGEPKCQRPR TLMRQQSLQQ PLSQNQQGRQ 
    PSQPTTSQSL GQLQAHAASA PGSNPRAYGR GQARQGTSAG SKYRAAGGRS RSNPGSWDHV 
    VGQIRNRGLD MKSFLEGRMV VLSLVLGLSE QDDFANIPDL QNPGTQQNQN AQGDKRLPAG 
    GKAVNTAPVP GQTPHDESDR RTETRSSVSD LVNSLTSEML MLSPGSEEDE AHEGCSRENL 
    GRIQFSVGYN FQESTLTVKV MKAQELPAKD FSGTSDPFVK IYLLPDKKHK LETKVKRKNL 
    NPHWNETFLF EGFPYEKVVQ RVLYLQVLDY DRFSRNDPIG EVSIPLNKVD LTQMQTFWKD 
    LKPCSDGSGS RGELLLSLCY NPSANSIIVN IIKARNLKAM DIGGTSDPYV KVWLMYKDKR 
    VEKKKTVTKK RNLNPIFNES FAFDIPTEKL RETTIIITVM DKDKLSRNDV IGKIYLSWKS 
    GPGEVKHWKD MIARPRQPVA QWHQLKA

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.