NDUFB11 | ENSG00000147123 | NCBI 54539

Details for: NDUFB11

Gene ID: 54539

Symbol: NDUFB11

Ensembl ID: ENSG00000147123

Description: NADH:ubiquinone oxidoreductase subunit B11

Associated with

Complex i biogenesis
(R-HSA-6799198)
Metabolism
(R-HSA-1430728)
Respiratory electron transport
(R-HSA-611105)
Respiratory electron transport, atp synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
(R-HSA-163200)
The citric acid (tca) cycle and respiratory electron transport
(R-HSA-1428517)
Aerobic respiration
(GO:0009060)
Mitochondrial inner membrane
(GO:0005743)
Mitochondrial respiratory chain complex i
(GO:0005747)
Mitochondrial respiratory chain complex i assembly
(GO:0032981)
Mitochondrion
(GO:0005739)
Protein binding
(GO:0005515)
Proton motive force-driven mitochondrial atp synthesis
(GO:0042776)

Other Information

Proteins

NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial

Genular Protein ID: 1556300801

Symbol: NDUBB_HUMAN

Name: NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial

UniProtKB Accession Codes:

Q9NX14 Q5JRR3 Q5JRR4 Q6IAB6 Q8WZ96 Q9BXX9

Database IDs:

Citations:

PubMed ID: 10544803

Title: Cloning and tissue expressional characterization of a full-length cDNA encoding human neuronal protein P17.3.

PubMed ID: 10544803

DOI: 10.1023/a:1018734605214

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 12975309

Title: The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.

PubMed ID: 12975309

DOI: 10.1101/gr.1293003

PubMed ID: 15772651

Title: The DNA sequence of the human X chromosome.

PubMed ID: 15772651

DOI: 10.1038/nature03440

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12611891

Title: The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification.

PubMed ID: 12611891

DOI: 10.1074/jbc.c300064200

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25772934

Title: Mutations in NDUFB11, encoding a complex I component of the mitochondrial respiratory chain, cause microphthalmia with linear skin defects syndrome.

PubMed ID: 25772934

DOI: 10.1016/j.ajhg.2015.02.002

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 25921236

Title: Exome sequencing of patients with histiocytoid cardiomyopathy reveals a de novo NDUFB11 mutation that plays a role in the pathogenesis of histiocytoid cardiomyopathy.

PubMed ID: 25921236

DOI: 10.1002/ajmg.a.37138

PubMed ID: 27626371

Title: Accessory subunits are integral for assembly and function of human mitochondrial complex I.

PubMed ID: 27626371

DOI: 10.1038/nature19754

PubMed ID: 31206022

Title: BAP31 regulates mitochondrial function via interaction with Tom40 within ER-mitochondria contact sites.

PubMed ID: 31206022

DOI: 10.1126/sciadv.aaw1386

PubMed ID: 26741492

Title: A comprehensive genomic analysis reveals the genetic landscape of mitochondrial respiratory chain complex deficiencies.

PubMed ID: 26741492

DOI: 10.1371/journal.pgen.1005679

Sequence Information:

Length: 153
Mass: 17317
Checksum: 2AF8FDD248A86C41
Sequence:

MAAGLFGLSA RRLLAAAATR GLPAARVRWE SSFSRTVVAP SAVAGKRPPE PTTPWQEDPE 
PEDENLYEKN PDSHGYDKDP VLDVWNMRLV FFFGVSIILV LGSTFVAYLP DYRMKEWSRR 
EAERLVKYRE ANGLPIMESN CFDPSKIQLP EDE

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: NDUFB11

Associated with

Other Information

Cloning and tissue expressional characterization of a full-length cDNA encoding human neuronal protein P17.3. PubMed ID: 10544803

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. PubMed ID: 12975309

The DNA sequence of the human X chromosome. PubMed ID: 15772651

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification. PubMed ID: 12611891

Initial characterization of the human central proteome. PubMed ID: 21269460

An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. PubMed ID: 24275569

Mutations in NDUFB11, encoding a complex I component of the mitochondrial respiratory chain, cause microphthalmia with linear skin defects syndrome. PubMed ID: 25772934

N-terminome analysis of the human mitochondrial proteome. PubMed ID: 25944712

Exome sequencing of patients with histiocytoid cardiomyopathy reveals a de novo NDUFB11 mutation that plays a role in the pathogenesis of histiocytoid cardiomyopathy. PubMed ID: 25921236

Accessory subunits are integral for assembly and function of human mitochondrial complex I. PubMed ID: 27626371

BAP31 regulates mitochondrial function via interaction with Tom40 within ER-mitochondria contact sites. PubMed ID: 31206022

A comprehensive genomic analysis reveals the genetic landscape of mitochondrial respiratory chain complex deficiencies. PubMed ID: 26741492