Details for: RC3H2
Associated with
Other Information
Genular Protein ID: 839562079
Symbol: RC3H2_HUMAN
Name: Roquin-2
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10938276
Title: A human gene coding for a membrane-associated nucleic acid-binding protein.
PubMed ID: 10938276
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 17974005
Title: The full-ORF clone resource of the German cDNA consortium.
PubMed ID: 17974005
PubMed ID: 15164053
Title: DNA sequence and analysis of human chromosome 9.
PubMed ID: 15164053
DOI: 10.1038/nature02465
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 20412057
Title: The ROQUIN family of proteins localizes to stress granules via the ROQ domain and binds target mRNAs.
PubMed ID: 20412057
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 23550652
Title: Molecular control of Tfh-cell differentiation by Roquin family proteins.
PubMed ID: 23550652
DOI: 10.1111/imr.12056
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24448648
Title: Roquin-2 promotes ubiquitin-mediated degradation of ASK1 to regulate stress responses.
PubMed ID: 24448648
PubMed ID: 25697406
Title: Roquin binds microRNA-146a and Argonaute2 to regulate microRNA homeostasis.
PubMed ID: 25697406
DOI: 10.1038/ncomms7253
PubMed ID: 29186683
Title: TRIM48 Promotes ASK1 Activation and Cell Death through Ubiquitination-Dependent Degradation of the ASK1-Negative Regulator PRMT1.
PubMed ID: 29186683
PubMed ID: 26249698
Title: Structure of human Roquin-2 and its complex with constitutive-decay element RNA.
PubMed ID: 26249698
PubMed ID: 26489670
Title: New Insights into the RNA-Binding and E3 Ubiquitin Ligase Activities of Roquins.
PubMed ID: 26489670
DOI: 10.1038/srep15660
Sequence Information:
- Length: 1191
- Mass: 131669
- Checksum: 93633D8D83DC7409
- Sequence:
MPVQAAQWTE FLSCPICYNE FDENVHKPIS LGCSHTVCKT CLNKLHRKAC PFDQTAINTD IDVLPVNFAL LQLVGAQVPD HQSIKLSNLG ENKHYEVAKK CVEDLALYLK PLSGGKGVAS LNQSALSRPM QRKLVTLVNC QLVEEEGRVR AMRAARSLGE RTVTELILQH QNPQQLSANL WAAVRARGCQ FLGPAMQEEA LKLVLLALED GSALSRKVLV LFVVQRLEPR FPQASKTSIG HVVQLLYRAS CFKVTKRDED SSLMQLKEEF RSYEALRREH DAQIVHIAME AGLRISPEQW SSLLYGDLAH KSHMQSIIDK LQSPESFAKS VQELTIVLQR TGDPANLNRL RPHLELLANI DPNPDAVSPT WEQLENAMVA VKTVVHGLVD FIQNYSRKGH ETPQPQPNSK YKTSMCRDLR QQGGCPRGTN CTFAHSQEEL EKYRLRNKKI NATVRTFPLL NKVGVNNTVT TTAGNVISVI GSTETTGKIV PSTNGISNAE NSVSQLISRS TDSTLRALET VKKVGKVGAN GQNAAGPSAD SVTENKIGSP PKTPVSNVAA TSAGPSNVGT ELNSVPQKSS PFLTRVPVYP PHSENIQYFQ DPRTQIPFEV PQYPQTGYYP PPPTVPAGVA PCVPRFVRSN NVPESSLPPA SMPYADHYST FSPRDRMNSS PYQPPPPQPY GPVPPVPSGM YAPVYDSRRI WRPPMYQRDD IIRSNSLPPM DVMHSSVYQT SLRERYNSLD GYYSVACQPP SEPRTTVPLP REPCGHLKTS CEEQIRRKPD QWAQYHTQKA PLVSSTLPVA TQSPTPPSPL FSVDFRADFS ESVSGTKFEE DHLSHYSPWS CGTIGSCINA IDSEPKDVIA NSNAVLMDLD SGDVKRRVHL FETQRRTKEE DPIIPFSDGP IISKWGAISR SSRTGYHTTD PVQATASQGS ATKPISVSDY VPYVNAVDSR WSSYGNEATS SAHYVERDRF IVTDLSGHRK HSSTGDLLSL ELQQAKSNSL LLQREANALA MQQKWNSLDE GRHLTLNLLS KEIELRNGEL QSDYTEDATD TKPDRDIELE LSALDTDEPD GQSEPIEEIL DIQLGISSQN DQLLNGMAVE NGHPVQQHQK EPPKQKKQSL GEDHVILEEQ KTILPVTSCF SQPLPVSISN ASCLPITTSV SAGNLILKTH VMSEDKNDFL KPVANGKMVN S
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.