Details for: UGT1A6

Gene ID: 54578

Symbol: UGT1A6

Ensembl ID: ENSG00000167165

Description: UDP glucuronosyltransferase family 1 member A6

Associated with

Other Information

Genular Protein ID: 1143302981

Symbol: UD16_HUMAN

Name: UDP-glucuronosyltransferase 1-6

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 1339448

Title: A novel complex locus UGT1 encodes human bilirubin, phenol, and other UDP-glucuronosyltransferase isozymes with identical carboxyl termini.

PubMed ID: 1339448

DOI: 10.1016/s0021-9258(19)50724-4

PubMed ID: 3141926

Title: Cloning and substrate specificity of a human phenol UDP-glucuronosyltransferase expressed in COS-7 cells.

PubMed ID: 3141926

DOI: 10.1073/pnas.85.22.8381

PubMed ID: 11434514

Title: Thirteen UDP-glucuronosyltransferase genes are encoded at the human UGT1 gene complex locus.

PubMed ID: 11434514

DOI: 10.1097/00008571-200106000-00011

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9466822

Title: Aryl hydrocarbon receptor-inducible or constitutive expression of human UDP glucuronosyltransferase UGT1A6.

PubMed ID: 9466822

DOI: 10.1006/abbi.1997.0485

PubMed ID: 18004212

Title: Genetic diversity at the UGT1 locus is amplified by a novel 3' alternative splicing mechanism leading to nine additional UGT1A proteins that act as regulators of glucuronidation activity.

PubMed ID: 18004212

DOI: 10.1097/fpc.0b013e3282f1f118

PubMed ID: 20610558

Title: Alternatively spliced products of the UGT1A gene interact with the enzymatically active proteins to inhibit glucuronosyltransferase activity in vitro.

PubMed ID: 20610558

DOI: 10.1124/dmd.110.034835

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 9429234

Title: Genetic polymorphism in the human UGT1A6 (planar phenol) UDP-glucuronosyltransferase: pharmacological implications.

PubMed ID: 9429234

DOI: 10.1097/00008571-199712000-00007

PubMed ID: 15284531

Title: Human UGT1A6 pharmacogenetics: identification of a novel SNP, characterization of allele frequencies and functional analysis of recombinant allozymes in human liver tissue and in cultured cells.

PubMed ID: 15284531

DOI: 10.1097/01.fpc.0000114771.78957.cb

PubMed ID: 19204906

Title: Analysis of inherited genetic variations at the UGT1 locus in the French-Canadian population.

PubMed ID: 19204906

DOI: 10.1002/humu.20946

Sequence Information:

  • Length: 532
  • Mass: 60751
  • Checksum: 4A9EA6A88CBC3136
  • Sequence:
  • MACLLRSFQR ISAGVFFLAL WGMVVGDKLL VVPQDGSHWL SMKDIVEVLS DRGHEIVVVV 
    PEVNLLLKES KYYTRKIYPV PYDQEELKNR YQSFGNNHFA ERSFLTAPQT EYRNNMIVIG 
    LYFINCQSLL QDRDTLNFFK ESKFDALFTD PALPCGVILA EYLGLPSVYL FRGFPCSLEH 
    TFSRSPDPVS YIPRCYTKFS DHMTFSQRVA NFLVNLLEPY LFYCLFSKYE ELASAVLKRD 
    VDIITLYQKV SVWLLRYDFV LEYPRPVMPN MVFIGGINCK KRKDLSQEFE AYINASGEHG 
    IVVFSLGSMV SEIPEKKAMA IADALGKIPQ TVLWRYTGTR PSNLANNTIL VKWLPQNDLL 
    GHPMTRAFIT HAGSHGVYES ICNGVPMVMM PLFGDQMDNA KRMETKGAGV TLNVLEMTSE 
    DLENALKAVI NDKSYKENIM RLSSLHKDRP VEPLDLAVFW VEFVMRHKGA PHLRPAAHDL 
    TWYQYHSLDV IGFLLAVVLT VAFITFKCCA YGYRKCLGKK GRVKKAHKSK TH

Genular Protein ID: 2458213257

Symbol: Q5DT01_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 14672974

Title: Multiple variable first exons: a mechanism for cell- and tissue-specific gene regulation.

PubMed ID: 14672974

DOI: 10.1101/gr.1225204

Sequence Information:

  • Length: 534
  • Mass: 60338
  • Checksum: 9C5833652A4D9B3D
  • Sequence:
  • MATGLQVPLP WLATGLLLLL SVQPWAESGK VLVVPIDGSH WLSMREVLRE LHARGHQAVV 
    LTPEVNMHIK EENFFTLTTY AISWTQDEFD RHVLGHTQLY FETEHFLKKF FRSMAMLNNM 
    SLVYHRSCVE LLHNEALIRH LNATSFDVVL TDPVNLCAAV LAKYLSIPTV FFLRNIPCDL 
    DFKGTQCPNP SSYIPRLLTT NSDHMTFMQR VKNMLYPLAL SYICHAFSAP YASLASELFQ 
    REVSVVDILS HASVWLFRGD FVMDYPRPIM PNMVFIGGIN CANRKPLSQE FEAYINASGE 
    HGIVVFSLGS MVSEIPEKKA MAIADALGKI PQTVLWRYTG TRPSNLANNT ILVKWLPQND 
    LLGHPMTRAF ITHAGSHGVY ESICNGVPMV MMPLFGDQMD NAKRMETKGA GVTLNVLEMT 
    SEDLENALKA VINDKSYKEN IMRLSSLHKD RPVEPLDLAV FWVEFVMRHK GAPHLRPAAH 
    DLTWYQYHSL DVIGFLLAVV LTVAFITFKC CAYGYRKCLG KKGRVKKAHK SKTH

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.