Foxo4 | ENSMUSG00000042903 | NCBI 54601

Details for: Foxo4

Gene ID: 54601

Symbol: Foxo4

Ensembl ID: ENSMUSG00000042903

Description: forkhead box O4

Associated with

Akt phosphorylates targets in the nucleus
(R-MMU-198693)
Deubiquitination
(R-MMU-5688426)
Foxo-mediated transcription
(R-MMU-9614085)
Foxo-mediated transcription of cell cycle genes
(R-MMU-9617828)
Foxo-mediated transcription of oxidative stress, metabolic and neuronal genes
(R-MMU-9615017)
Gene expression (transcription)
(R-MMU-74160)
Generic transcription pathway
(R-MMU-212436)
Intracellular signaling by second messengers
(R-MMU-9006925)
Metabolism of proteins
(R-MMU-392499)
Pip3 activates akt signaling
(R-MMU-1257604)
Post-translational protein modification
(R-MMU-597592)
Regulation of localization of foxo transcription factors
(R-MMU-9614399)
Rna polymerase ii transcription
(R-MMU-73857)
Signal transduction
(R-MMU-162582)
Ub-specific processing proteases
(R-MMU-5689880)
Beta-catenin binding
(GO:0008013)
Cell cycle
(GO:0007049)
Cell differentiation
(GO:0030154)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Dna-binding transcription activator activity, rna polymerase ii-specific
(GO:0001228)
Dna-binding transcription factor activity
(GO:0003700)
Dna-binding transcription factor activity, rna polymerase ii-specific
(GO:0000981)
Dna-binding transcription factor binding
(GO:0140297)
Dna binding
(GO:0003677)
Enzyme binding
(GO:0019899)
Identical protein binding
(GO:0042802)
Insulin receptor signaling pathway
(GO:0008286)
Mitotic g2 dna damage checkpoint signaling
(GO:0007095)
Multicellular organism development
(GO:0007275)
Muscle organ development
(GO:0007517)
Negative regulation of angiogenesis
(GO:0016525)
Negative regulation of cell population proliferation
(GO:0008285)
Negative regulation of g0 to g1 transition
(GO:0070317)
Negative regulation of smooth muscle cell differentiation
(GO:0051151)
Nuclear speck
(GO:0016607)
Nucleic acid binding
(GO:0003676)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Positive regulation of dna-templated transcription
(GO:0045893)
Positive regulation of smooth muscle cell migration
(GO:0014911)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Promoter-specific chromatin binding
(GO:1990841)
Protein binding
(GO:0005515)
Regulation of dna-templated transcription
(GO:0006355)
Regulation of transcription by rna polymerase ii
(GO:0006357)
Response to oxidative stress
(GO:0006979)
Rna polymerase ii cis-regulatory region sequence-specific dna binding
(GO:0000978)
Sequence-specific dna binding
(GO:0043565)
Sequence-specific double-stranded dna binding
(GO:1990837)
Stem cell differentiation
(GO:0048863)

Other Information

Proteins

Forkhead box protein O4
Q4KL34_MOUSE

Genular Protein ID: 129142243

Symbol: FOXO4_MOUSE

Name: Forkhead box protein O4

UniProtKB Accession Codes:

Q9WVH3

Database IDs:

Citations:

PubMed ID: 11353388

Title: Identification and characterization of members of the FKHR (FOX O) subclass of winged-helix transcription factors in the mouse.

PubMed ID: 11353388

DOI: 10.1007/s003350020002

PubMed ID: 16054032

Title: Phenotypic modulation of smooth muscle cells through interaction of Foxo4 and myocardin.

PubMed ID: 16054032

DOI: 10.1016/j.devcel.2005.05.017

PubMed ID: 22510882

Title: Novel repressor regulates insulin sensitivity through interaction with Foxo1.

PubMed ID: 22510882

DOI: 10.1038/emboj.2012.97

PubMed ID: 22956541

Title: Foxk1 promotes cell proliferation and represses myogenic differentiation by regulating Foxo4 and Mef2.

PubMed ID: 22956541

DOI: 10.1242/jcs.105239

Sequence Information:

Length: 505
Mass: 53649
Checksum: ABB99B54807C7CE5
Sequence:

MDPENKKSAT GAAAILDLDP DFEPQSRPRS CTWPLPRPDL ATEPHEPSEV EPSLGQKVPT 
EGHSEPILLP SRLPEPAGGP QPGILGAVTG PRKGGSRRNA WGNQSYAELI SQAIESAPEK 
RLTLAQIYEW MVRTVPYFKD KGDSNSSAGW KNSIRHNLSL HSKFIKVHNE ATGKSSWWML 
NPDGGKGGKA PRRRAASMDS SSKLLRGRSK GPKKKPSVLP APPEGATPRS PLGHFAKWSS 
SPCPRNREEA DVWTTFRPRS SSNASTVSTR LSPMRPESEV LAEEEMPASA SSYAGGVPPT 
LSEDLELLDG LNLASPHSLL SRSGLSGFSL QHPGLAGPLH SYGASLFGPI DGSLSAGEGC 
FSSSQSLEAL LTSDTPPPPA DVLMTQVDPI LSQAPTLLLL GGMPSSSKLG TGVSLCPTPL 
EGPGPSNLVP NLSVMAPPPV MAGAPIPKVL GTPVLASPTE DSSHDRMPQD LDLDMYMENL 
ECDMDNIISD LMDGEGLDFN FEPDP

Genular Protein ID: 3926827368

Symbol: Q4KL34_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q4KL34

Database IDs:

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

Length: 200
Mass: 21821
Checksum: 3CFBD944E7DF8E97
Sequence:

MDPENKKSAT GAAAILDLDP DFEPQSRPRS CTWPLPRPDL ATEPHEPSEV EPSLGQKVPT 
EGHSEPILLP SRLPEPAGGP QPGILGAVTG PRKGGSRRNA WGNQSYAELI SQAIESAPEK 
RLTLAQIYEW MVRTVPYFKD KGDSNSSAGW KVVCVSVPST ADRMDLHVDV RVREQIYNVR 
RGQTEQKMGQ LTETLGAISG

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Foxo4

Associated with

Other Information

Identification and characterization of members of the FKHR (FOX O) subclass of winged-helix transcription factors in the mouse. PubMed ID: 11353388

Phenotypic modulation of smooth muscle cells through interaction of Foxo4 and myocardin. PubMed ID: 16054032

Novel repressor regulates insulin sensitivity through interaction with Foxo1. PubMed ID: 22510882