DDX56 | ENSG00000136271 | NCBI 54606

Details for: DDX56

Gene ID: 54606

Symbol: DDX56

Ensembl ID: ENSG00000136271

Description: DEAD-box helicase 56

Associated with

Atp binding
(GO:0005524)
Atp hydrolysis activity
(GO:0016887)
Cytosol
(GO:0005829)
Defense response to virus
(GO:0051607)
Membrane
(GO:0016020)
Modulation by host of viral rna genome replication
(GO:0044830)
Negative regulation of type i interferon production
(GO:0032480)
Nucleolus
(GO:0005730)
Nucleus
(GO:0005634)
Positive regulation of neuron projection development
(GO:0010976)
Protein binding
(GO:0005515)
Protein sequestering activity
(GO:0140311)
Rna binding
(GO:0003723)
Rna helicase activity
(GO:0003724)
Rna stem-loop binding
(GO:0035613)
Rrna processing
(GO:0006364)

Other Information

Proteins

Probable ATP-dependent RNA helicase DDX56

Genular Protein ID: 3950869267

Symbol: DDX56_HUMAN

Name: Probable ATP-dependent RNA helicase DDX56

UniProtKB Accession Codes:

Q9NY93 A4D2K9 C9JV95 Q6IAE2 Q9H9I8

Database IDs:

Citations:

PubMed ID: 10749921

Title: A novel helicase-type protein in the nucleolus: protein NOH61.

PubMed ID: 10749921

DOI: 10.1091/mbc.11.4.1153

PubMed ID: 11230166

Title: Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.

PubMed ID: 11230166

DOI: 10.1101/gr.gr1547r

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 12853948

Title: The DNA sequence of human chromosome 7.

PubMed ID: 12853948

DOI: 10.1038/nature01782

PubMed ID: 12690205

Title: Human chromosome 7: DNA sequence and biology.

PubMed ID: 12690205

DOI: 10.1126/science.1083423

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12429849

Title: Functional proteomic analysis of human nucleolus.

PubMed ID: 12429849

DOI: 10.1091/mbc.e02-05-0271

PubMed ID: 17525332

Title: ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.

PubMed ID: 17525332

DOI: 10.1126/science.1140321

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22925334

Title: The helicase activity of DDX56 is required for its role in assembly of infectious West Nile virus particles.

PubMed ID: 22925334

DOI: 10.1016/j.virol.2012.08.011

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 31340999

Title: DDX56 inhibits type I interferon by disrupting assembly of IRF3-IPO5 to inhibit IRF3 nucleus import.

PubMed ID: 31340999

DOI: 10.1242/jcs.230409

PubMed ID: 31445188

Title: DDX56 cooperates with FMDV 3A to enhance FMDV replication by inhibiting the phosphorylation of IRF3.

PubMed ID: 31445188

DOI: 10.1016/j.cellsig.2019.109393

PubMed ID: 33789112

Title: The DEAD-box helicase DDX56 is a conserved stemness regulator in normal and cancer stem cells.

PubMed ID: 33789112

DOI: 10.1016/j.celrep.2021.108903

PubMed ID: 34922148

Title: DDX56 antagonizes IFN-beta production to enhance EMCV replication by inhibiting IRF3 nuclear translocation.

PubMed ID: 34922148

DOI: 10.1016/j.vetmic.2021.109304

Sequence Information:

Length: 547
Mass: 61590
Checksum: 6D127CDAA73610D2
Sequence:

MEDSEALGFE HMGLDPRLLQ AVTDLGWSRP TLIQEKAIPL ALEGKDLLAR ARTGSGKTAA 
YAIPMLQLLL HRKATGPVVE QAVRGLVLVP TKELARQAQS MIQQLATYCA RDVRVANVSA 
AEDSVSQRAV LMEKPDVVVG TPSRILSHLQ QDSLKLRDSL ELLVVDEADL LFSFGFEEEL 
KSLLCHLPRI YQAFLMSATF NEDVQALKEL ILHNPVTLKL QESQLPGPDQ LQQFQVVCET 
EEDKFLLLYA LLKLSLIRGK SLLFVNTLER SYRLRLFLEQ FSIPTCVLNG ELPLRSRCHI 
ISQFNQGFYD CVIATDAEVL GAPVKGKRRG RGPKGDKASD PEAGVARGID FHHVSAVLNF 
DLPPTPEAYI HRAGRTARAN NPGIVLTFVL PTEQFHLGKI EELLSGENRG PILLPYQFRM 
EEIEGFRYRC RDAMRSVTKQ AIREARLKEI KEELLHSEKL KTYFEDNPRD LQLLRHDLPL 
HPAVVKPHLG HVPDYLVPPA LRGLVRPHKK RKKLSSSCRK AKRAKSQNPL RSFKHKGKKF 
RPTAKPS

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: DDX56

Associated with

Other Information

A novel helicase-type protein in the nucleolus: protein NOH61. PubMed ID: 10749921

Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. PubMed ID: 11230166

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

The DNA sequence of human chromosome 7. PubMed ID: 12853948

Human chromosome 7: DNA sequence and biology. PubMed ID: 12690205

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Functional proteomic analysis of human nucleolus. PubMed ID: 12429849

ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage. PubMed ID: 17525332

Initial characterization of the human central proteome. PubMed ID: 21269460

The helicase activity of DDX56 is required for its role in assembly of infectious West Nile virus particles. PubMed ID: 22925334

Toward a comprehensive characterization of a human cancer cell phosphoproteome. PubMed ID: 23186163

An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. PubMed ID: 24275569

DDX56 inhibits type I interferon by disrupting assembly of IRF3-IPO5 to inhibit IRF3 nucleus import. PubMed ID: 31340999

DDX56 cooperates with FMDV 3A to enhance FMDV replication by inhibiting the phosphorylation of IRF3. PubMed ID: 31445188

The DEAD-box helicase DDX56 is a conserved stemness regulator in normal and cancer stem cells. PubMed ID: 33789112

DDX56 antagonizes IFN-beta production to enhance EMCV replication by inhibiting IRF3 nuclear translocation. PubMed ID: 34922148