Socs6 | ENSMUSG00000056153 | NCBI 54607

Details for: Socs6

Gene ID: 54607

Symbol: Socs6

Ensembl ID: ENSMUSG00000056153

Description: suppressor of cytokine signaling 6

Associated with

Cytokine signaling in immune system
(R-MMU-1280215)
Flt3 signaling
(R-MMU-9607240)
Immune system
(R-MMU-168256)
Metabolism of proteins
(R-MMU-392499)
Neddylation
(R-MMU-8951664)
Negative regulation of flt3
(R-MMU-9706369)
Post-translational protein modification
(R-MMU-597592)
1-phosphatidylinositol-3-kinase regulator activity
(GO:0046935)
Cytosol
(GO:0005829)
Immunological synapse
(GO:0001772)
Intracellular glucose homeostasis
(GO:0001678)
Intracellular signal transduction
(GO:0035556)
Negative regulation of signal transduction
(GO:0009968)
Negative regulation of t cell activation
(GO:0050868)
Phosphatidylinositol 3-kinase complex
(GO:0005942)
Phosphatidylinositol phosphate biosynthetic process
(GO:0046854)
Proteasomal protein catabolic process
(GO:0010498)
Protein binding
(GO:0005515)
Protein ubiquitination
(GO:0016567)
Regulation of growth
(GO:0040008)

Other Information

Proteins

Suppressor of cytokine signaling 6

Genular Protein ID: 2869892330

Symbol: SOCS6_MOUSE

Name: Suppressor of cytokine signaling 6

UniProtKB Accession Codes:

Q9JLY0 Q8VEN5 Q9D2A0

Database IDs:

Citations:

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12052866

Title: SOCS-6 binds to insulin receptor substrate 4, and mice lacking the SOCS-6 gene exhibit mild growth retardation.

PubMed ID: 12052866

DOI: 10.1128/mcb.22.13.4567-4578.2002

PubMed ID: 16643902

Title: The E3 ubiquitin ligase HOIL-1 induces the polyubiquitination and degradation of SOCS6 associated proteins.

PubMed ID: 16643902

DOI: 10.1016/j.febslet.2006.03.093

PubMed ID: 21099329

Title: Pim3 negatively regulates glucose-stimulated insulin secretion.

PubMed ID: 21099329

DOI: 10.4161/isl.2.5.13058

Sequence Information:

Length: 533
Mass: 59077
Checksum: F779C6519DB0A17B
Sequence:

MKKISLKTFR KSFNLSKSKD ETEFMVVQPQ SLAGDFVKDD SLFGSCYGKD MASCDIGSED 
EKGKNRSKSE SLMGTLKRRL SAKQKTKGKG GTASTDEDTF SSASAPGGLK DVRAPRPIRS 
TSLRSHHYSP TPWPLRPTSS EETCIKMEMR VKALVHAASP GPVNGVRKDL RELQPRELRD 
LQPEPRPESR CSPSSPGDLS LHLEEHVPVV IGLMSQDYLQ YTVPLDDGMC PLEGPRSCCL 
DTSSPMEVSA VPLPGASGAF SEDDSHVDQD LVVGPEILVD SSVNNLLIGT TGVMLQSPRG 
GHDDAPPLSP LLPPMQNNPI QRNFSGLSGP DLHMAESVRC HLNFDPNSAP GVARVYDSVQ 
SSGPMVVTSL TEELKKLAKQ GWYWGPITRW EAEGKLANVP DGSFLVRDSS DDRYLLSLSF 
RSHGKTLHTR IEHSNGRFSF YEQPDVEGHT SIVDLIEHSI RDSENGAFCY SRSRLPGSAT 
YPVRLTNPVS RFMQVRSLQY LCRFVIRQYT RIDLIQKLPL PNKMKDYLQE KHY

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Socs6

Associated with

Other Information

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

SOCS-6 binds to insulin receptor substrate 4, and mice lacking the SOCS-6 gene exhibit mild growth retardation. PubMed ID: 12052866