Details for: Sfrp5

Gene ID: 54612

Symbol: Sfrp5

Ensembl ID: ENSMUSG00000018822

Description: secreted frizzled-related sequence protein 5

Associated with

  • Canonical wnt signaling pathway
    (GO:0060070)
  • Cell differentiation
    (GO:0030154)
  • Convergent extension involved in axis elongation
    (GO:0060028)
  • Digestive tract morphogenesis
    (GO:0048546)
  • Extracellular region
    (GO:0005576)
  • Extracellular space
    (GO:0005615)
  • Multicellular organism development
    (GO:0007275)
  • Negative regulation of canonical wnt signaling pathway
    (GO:0090090)
  • Negative regulation of cell population proliferation
    (GO:0008285)
  • Negative regulation of jun kinase activity
    (GO:0043508)
  • Negative regulation of non-canonical wnt signaling pathway
    (GO:2000051)
  • Negative regulation of phosphatidylinositol 3-kinase/protein kinase b signal transduction
    (GO:0051898)
  • Negative regulation of planar cell polarity pathway involved in axis elongation
    (GO:2000041)
  • Negative regulation of wnt signaling pathway
    (GO:0030178)
  • Non-canonical wnt signaling pathway
    (GO:0035567)
  • Planar cell polarity pathway involved in axis elongation
    (GO:0003402)
  • Planar cell polarity pathway involved in neural tube closure
    (GO:0090179)
  • Post-anal tail morphogenesis
    (GO:0036342)
  • Regulation of establishment of planar polarity
    (GO:0090175)
  • Regulation of transcription by rna polymerase ii
    (GO:0006357)
  • Wnt-protein binding
    (GO:0017147)
  • Wnt signaling pathway
    (GO:0016055)

Other Information

Genular Protein ID: 2610034096

Symbol: SFRP5_MOUSE

Name: Secreted frizzled-related protein 5

UniProtKB Accession Codes:

Q9WU66 Q8K269

Database IDs:

AGR 1 AlphaFoldDB 1 BioGRID 1 BioGRID-ORCS 1 CCDS 1 CDD 2 CTD 1 ChiTaRS 1 DNASU 1 EMBL 2 GO 17 Gene3D 2 InParanoid 1 InterPro 7 KEGG 1 MGI 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRO 1 PROSITE 2 PROSITE-ProRule 2 PaxDb 1 Pfam 2 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 RefSeq 1 SMART 2 SMR 1 STRING 1 SUPFAM 2 TreeFam 1 UCSC 1 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 10072424

Title: Cloning and characterization of a secreted frizzled-related protein that is expressed by the retinal pigment epithelium.

PubMed ID: 10072424

DOI: 10.1093/hmg/8.4.575

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 314
  • Mass: 35382
  • Checksum: 296847F56D1CAFDD
  • Sequence:
    • MWVAWSARTA ALALLLGALH GAPTRGQEYD YYGWQAEPLH GRSYSKPPQC LDIPADLPLC 
HTVGYKRMRL PNLLEHESLA EVKQQASSWL PLLAKRCHSD TQVFLCSLFA PVCLDRPIYP 
CRSLCEAARA GCAPLMEAYG FPWPEMLHCH KFPLDNDLCI AVQFGHLPAT APPVTKICAQ 
CEMEHSADGL MEQMCSSDFV VKMRIKEIKI DNGDRKLIGA QKKKKLLKAG PLKRKDTKKL 
VLHMKNGASC PCPQLDNLTG SFLVMGRKVE GQLLLTAVYR WDKKNKEMKF AVKFMFSYPC 
SLYYPFFYGA AEPH

Genular Protein ID: 3352842477

Symbol: A0A0R4J001_MOUSE

Name: N/A

UniProtKB Accession Codes:

A0A0R4J001

Database IDs:

AGR 1 ARBA 6 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 2 CTD 1 ChiTaRS 1 DNASU 1 Ensembl 2 GO 9 Gene3D 2 GeneTree 1 InterPro 7 KEGG 1 MGI 2 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PROSITE 4 PROSITE-ProRule 1 Pfam 2 PhylomeDB 1 Proteomes 2 ProteomicsDB 2 RefSeq 1 SAM 1 SMART 2 SMR 1 SUPFAM 2 VEuPathDB 1

Citations:

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

Sequence Information:

  • Length: 314
  • Mass: 35410
  • Checksum: 29775FF26513B7DA
  • Sequence:
    • MWVAWSARTA ALALLLGALH GAPTRGQEYD YYGWQAEPLH GRSYSKPPQC LDIPADLPLC 
HTVGYKRMRL PNLLEHESLA EVKQQASSWL PLLAKRCHSD TQVFLCSLFA PVCLDRPIYP 
CRSLCEAVRA GCAPLMEAYG FPWPEMLHCH KFPLDNDLCI AVQFGHLPAT APPVTKICAQ 
CEMEHSADGL MEQMCSSDFV VKMRIKEIKI DNGDRKLIGA QKKKKLLKAG PLKRKDTKKL 
VLHMKNGASC PCPQLDNLTG SFLVMGRKVE GQLLLTAVYR WDKKNKEMKF AVKFMFSYPC 
SLYYPFFYGA AEPH

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.