Paf1 | ENSMUSG00000003437 | NCBI 54624

Details for: Paf1

Gene ID: 54624

Symbol: Paf1

Ensembl ID: ENSMUSG00000003437

Description: Paf1, RNA polymerase II complex component

Associated with

E3 ubiquitin ligases ubiquitinate target proteins
(R-MMU-8866654)
Formation of rna pol ii elongation complex
(R-MMU-112382)
Gene expression (transcription)
(R-MMU-74160)
Metabolism of proteins
(R-MMU-392499)
Post-translational protein modification
(R-MMU-597592)
Protein ubiquitination
(R-MMU-8852135)
Rna polymerase ii pre-transcription events
(R-MMU-674695)
Rna polymerase ii transcription
(R-MMU-73857)
Rna polymerase ii transcription elongation
(R-MMU-75955)
Cdc73/paf1 complex
(GO:0016593)
Cellular response to lipopolysaccharide
(GO:0071222)
Chromatin binding
(GO:0003682)
Cytoplasm
(GO:0005737)
Endodermal cell fate commitment
(GO:0001711)
Fibrillar center
(GO:0001650)
Intracellular membrane-bounded organelle
(GO:0043231)
Membrane
(GO:0016020)
Mrna 3'-end processing
(GO:0031124)
Negative regulation of myeloid cell differentiation
(GO:0045638)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Positive regulation of cell cycle g1/s phase transition
(GO:1902808)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Protein binding
(GO:0005515)
Protein localization to nucleus
(GO:0034504)
Rna polymerase ii complex binding
(GO:0000993)
Stem cell population maintenance
(GO:0019827)
Transcription elongation by rna polymerase ii
(GO:0006368)
Wnt signaling pathway
(GO:0016055)

Other Information

Proteins

RNA polymerase II-associated factor 1 homolog

Genular Protein ID: 2648076608

Symbol: PAF1_MOUSE

Name: RNA polymerase II-associated factor 1 homolog

UniProtKB Accession Codes:

Q8K2T8 Q3UY97 Q9CS63 Q9JJ99

Database IDs:

Citations:

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 19345177

Title: A genome-scale RNAi screen for Oct4 modulators defines a role of the Paf1 complex for embryonic stem cell identity.

PubMed ID: 19345177

DOI: 10.1016/j.stem.2009.03.009

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 27749823

Title: Regulation of transcriptional elongation in pluripotency and cell differentiation by the PHD-finger protein Phf5a.

PubMed ID: 27749823

DOI: 10.1038/ncb3424

Sequence Information:

Length: 535
Mass: 60518
Checksum: 7A5EAB1284988070
Sequence:

MAPTIQTQAQ REDGHRPNSH RTLPERSGVV CRVKYCNSLP DIPFDPKFIT YPFDQNRFVQ 
YKATSLEKQH KHDLLTEPDL GVTIDLINPD TYRIDPNVLL DPADEKLLEE EIQAPTSSKR 
SQQHAKVVPW MRKTEYISTE FNRYGISNEK PEVKIGVSVK QQFTEEEIYK DRDSQITAIE 
KTFEDAQKSI SQHYSKPRVT PVEVMPVFPD FKMWINPCAQ VIFDSDPAPK DTSGAAALEM 
MSQAMIRGMM DEEGNQFVAY FLPVEETLKK RKRDQEEEMD YAPDDVYDYK IAREYNWNVK 
NKASKGYEEN YFFIFREGDG VYYNELETRV RLSKRRAKAG VQSGTNALLV VKHRDMNEKE 
LEAQEARKAQ LENHEPEEEE EEEMEAEEKE AGGSDEEQEK GSSSEKEGSE DEHSGSESDR 
EEGDRDEASD KSGSGEDESS EDEARAARDK EEIFGSDADS EDDADSDDED RGQAHRGSDN 
DSDSGSDGGG QRSRSQSRSR SRSASPFPSG SEHSAQEDGS EAAASDSSEA DSDSD

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Paf1

Associated with

Other Information

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

A genome-scale RNAi screen for Oct4 modulators defines a role of the Paf1 complex for embryonic stem cell identity. PubMed ID: 19345177