Usp27x | ENSMUSG00000046269 | NCBI 54651

Details for: Usp27x

Gene ID: 54651

Symbol: Usp27x

Ensembl ID: ENSMUSG00000046269

Description: ubiquitin specific peptidase 27, X chromosome

Associated with

Cysteine-type deubiquitinase activity
(GO:0004843)
Cysteine-type endopeptidase activity
(GO:0004197)
Cysteine-type peptidase activity
(GO:0008234)
Cytoplasm
(GO:0005737)
Defense response to virus
(GO:0051607)
Hydrolase activity
(GO:0016787)
Immune system process
(GO:0002376)
Innate immune response
(GO:0045087)
K48-linked deubiquitinase activity
(GO:1990380)
K63-linked deubiquitinase activity
(GO:0061578)
Nucleus
(GO:0005634)
Peptidase activity
(GO:0008233)
Positive regulation of apoptotic process
(GO:0043065)
Positive regulation of type i interferon-mediated signaling pathway
(GO:0060340)
Protein binding
(GO:0005515)
Protein deubiquitination
(GO:0016579)
Protein k48-linked deubiquitination
(GO:0071108)
Protein k63-linked deubiquitination
(GO:0070536)
Protein stabilization
(GO:0050821)
Proteolysis
(GO:0006508)

Other Information

Proteins

Ubiquitin carboxyl-terminal hydrolase 27

Genular Protein ID: 2667061565

Symbol: UBP27_MOUSE

Name: Ubiquitin carboxyl-terminal hydrolase 27

UniProtKB Accession Codes:

Q8CEG8 B1ATV2 Q8BSW2 Q9JIG5

Database IDs:

Citations:

PubMed ID: 10857745

Title: A transcript map of a 2-Mb BAC contig in the proximal portion of the mouse X chromosome and regional mapping of the scurfy mutation.

PubMed ID: 10857745

DOI: 10.1006/geno.2000.6173

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 27013495

Title: The deubiquitinase Usp27x stabilizes the BH3-only protein Bim and enhances apoptosis.

PubMed ID: 27013495

DOI: 10.15252/embr.201541392

PubMed ID: 31534008

Title: USP27X deubiquitinates and stabilizes the DNA sensor cGAS to regulate cytosolic DNA-mediated signaling.

PubMed ID: 31534008

DOI: 10.4049/jimmunol.1900514

Sequence Information:

Length: 438
Mass: 49599
Checksum: 159B156E0E00FEB9
Sequence:

MCKDYVYDID IEQIAKEEQG EALKLQASTS TEVSQQQCSV PGLGEKYPTW ETTKPELELL 
GHNPRRRRIA SSFTIGLRGL INLGNTCFMN CIVQALTHTP ILRDFFLSDR HRCEMPSPEL 
CLVCEMSSLF RELYSGNPSP HVPYKLLHLV WIHARHLAGY RQQDAHEFLI AALDVLHRHC 
KGDDVGKVAS NPNHCNCIID QIFTGGLQSD VTCQACHGVS TTIDPCWDIS LDLPGSCTSF 
WPMSPGRESS LNGESHIPGI TTLTDCLRRF TRPEHLGSSA KIKCGSCQSY QESTKQLTMK 
KLPVVACFHF KRFEHSAKQR RKITTYISFP LELDMTPFMA SSKETRVNGQ LQLPTNSANN 
ENKYSLFAVV NHQGTLESGH YTSFIRHHRD QWFKCDDAVI TKASIKDVLD SEGYLLFYHK 
QVLEPEPEKV KEMTPQAY

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Usp27x

Associated with

Other Information

A transcript map of a 2-Mb BAC contig in the proximal portion of the mouse X chromosome and regional mapping of the scurfy mutation. PubMed ID: 10857745

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303