Prdx5 | ENSMUSG00000024953 | NCBI 54683

Details for: Prdx5

Gene ID: 54683

Symbol: Prdx5

Ensembl ID: ENSMUSG00000024953

Description: peroxiredoxin 5

Associated with

Cellular responses to stimuli
(R-MMU-8953897)
Cellular responses to stress
(R-MMU-2262752)
Cellular response to chemical stress
(R-MMU-9711123)
Detoxification of reactive oxygen species
(R-MMU-3299685)
Gene expression (transcription)
(R-MMU-74160)
Generic transcription pathway
(R-MMU-212436)
Rna polymerase ii transcription
(R-MMU-73857)
Tp53 regulates metabolic genes
(R-MMU-5628897)
Transcriptional regulation by tp53
(R-MMU-3700989)
Antioxidant activity
(GO:0016209)
Cell redox homeostasis
(GO:0045454)
Cellular response to oxidative stress
(GO:0034599)
Cellular response to reactive oxygen species
(GO:0034614)
Cysteine-type endopeptidase inhibitor activity involved in apoptotic process
(GO:0043027)
Cytoplasm
(GO:0005737)
Cytoplasmic vesicle
(GO:0031410)
Cytosol
(GO:0005829)
Hydrogen peroxide catabolic process
(GO:0042744)
Identical protein binding
(GO:0042802)
Intracellular membrane-bounded organelle
(GO:0043231)
Mitochondrion
(GO:0005739)
Nadph oxidation
(GO:0070995)
Negative regulation of apoptotic process
(GO:0043066)
Negative regulation of oxidoreductase activity
(GO:0051354)
Negative regulation of transcription by rna polymerase iii
(GO:0016480)
Nucleus
(GO:0005634)
Oxidoreductase activity
(GO:0016491)
Perinuclear region of cytoplasm
(GO:0048471)
Peroxidase activity
(GO:0004601)
Peroxisomal matrix
(GO:0005782)
Peroxisome
(GO:0005777)
Peroxynitrite reductase activity
(GO:0072541)
Positive regulation of collagen biosynthetic process
(GO:0032967)
Protein binding
(GO:0005515)
Reactive nitrogen species metabolic process
(GO:2001057)
Regulation of apoptosis involved in tissue homeostasis
(GO:0060785)
Response to oxidative stress
(GO:0006979)
Rna polymerase iii transcription regulatory region sequence-specific dna binding
(GO:0001016)
Signaling receptor binding
(GO:0005102)
Thioredoxin-dependent peroxiredoxin activity
(GO:0140824)
Thioredoxin peroxidase activity
(GO:0008379)

Other Information

Proteins

Peroxiredoxin-5, mitochondrial

Genular Protein ID: 659358523

Symbol: PRDX5_MOUSE

Name: Peroxiredoxin-5, mitochondrial

UniProtKB Accession Codes:

P99029 Q9QX45 Q9QZ75

Database IDs:

Citations:

PubMed ID: 10679306

Title: Mouse peroxiredoxin V is a thioredoxin peroxidase that inhibits p53-induced apoptosis.

PubMed ID: 10679306

DOI: 10.1006/bbrc.2000.2231

PubMed ID: 10514471

Title: Characterization of human and murine PMP20 peroxisomal proteins that exhibit antioxidant activity in vitro.

PubMed ID: 10514471

DOI: 10.1074/jbc.274.42.29897

PubMed ID: 10521424

Title: Cloning and characterization of AOEB166, a novel mammalian antioxidant enzyme of the peroxiredoxin family.

PubMed ID: 10521424

DOI: 10.1074/jbc.274.43.30451

PubMed ID: 10753630

Title: Molecular cloning and characterization of the mouse Peroxiredoxin V gene.

PubMed ID: 10753630

DOI: 10.1006/bbrc.2000.2430

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 23806337

Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.

PubMed ID: 23806337

DOI: 10.1016/j.molcel.2013.06.001

PubMed ID: 23576753

Title: Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways.

PubMed ID: 23576753

DOI: 10.1073/pnas.1302961110

PubMed ID: 31740833

Title: ABHD10 is an S-depalmitoylase affecting redox homeostasis through peroxiredoxin-5.

PubMed ID: 31740833

DOI: 10.1038/s41589-019-0399-y

Sequence Information:

Length: 210
Mass: 21897
Checksum: E944104CC468BDD8
Sequence:

MLQLGLRVLG CKASSVLRAS TCLAGRAGRK EAGWECGGAR SFSSSAVTMA PIKVGDAIPS 
VEVFEGEPGK KVNLAELFKG KKGVLFGVPG AFTPGCSKTH LPGFVEQAGA LKAKGAQVVA 
CLSVNDVFVI EEWGRAHQAE GKVRLLADPT GAFGKATDLL LDDSLVSLFG NRRLKRFSMV 
IDNGIVKALN VEPDGTGLTC SLAPNILSQL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Prdx5

Associated with

Other Information

Mouse peroxiredoxin V is a thioredoxin peroxidase that inhibits p53-induced apoptosis. PubMed ID: 10679306

Characterization of human and murine PMP20 peroxisomal proteins that exhibit antioxidant activity in vitro. PubMed ID: 10514471

Cloning and characterization of AOEB166, a novel mammalian antioxidant enzyme of the peroxiredoxin family. PubMed ID: 10521424

Molecular cloning and characterization of the mouse Peroxiredoxin V gene. PubMed ID: 10753630

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. PubMed ID: 23806337

Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways. PubMed ID: 23576753

ABHD10 is an S-depalmitoylase affecting redox homeostasis through peroxiredoxin-5. PubMed ID: 31740833