Details for: KIF1A

Gene ID: 547

Symbol: KIF1A

Ensembl ID: ENSG00000130294

Description: kinesin family member 1A

Associated with

Cells (max top 100)

(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: 2.77
    Marker Score: 12799
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 2.67
    Marker Score: 1559
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 2.57
    Marker Score: 5223
  • Cell Name: endocrine cell (CL0000163)
    Fold Change: 2.33
    Marker Score: 1204
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 2.2
    Marker Score: 2657
  • Cell Name: glycinergic amacrine cell (CL4030028)
    Fold Change: 2.19
    Marker Score: 2067.5
  • Cell Name: vip GABAergic cortical interneuron (CL4023016)
    Fold Change: 2.18
    Marker Score: 82966.5
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: 2.07
    Marker Score: 30879
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: 2.06
    Marker Score: 15798
  • Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 2.01
    Marker Score: 7783.5
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: 2
    Marker Score: 39786
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 2
    Marker Score: 20607.5
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 1.98
    Marker Score: 4184
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: 1.95
    Marker Score: 8081.5
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 1.95
    Marker Score: 65708
  • Cell Name: primary sensory neuron (sensu Teleostei) (CL0000531)
    Fold Change: 1.94
    Marker Score: 651
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: 1.92
    Marker Score: 40904
  • Cell Name: neuron (CL0000540)
    Fold Change: 1.9
    Marker Score: 7750
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: 1.89
    Marker Score: 69611
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: 1.87
    Marker Score: 17562
  • Cell Name: brainstem motor neuron (CL2000047)
    Fold Change: 1.84
    Marker Score: 1071
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.84
    Marker Score: 113211
  • Cell Name: type A enteroendocrine cell (CL0002067)
    Fold Change: 1.8
    Marker Score: 724
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 1.8
    Marker Score: 3402
  • Cell Name: peripheral nervous system neuron (CL2000032)
    Fold Change: 1.77
    Marker Score: 1985
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: 1.76
    Marker Score: 15120
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 1.75
    Marker Score: 2119
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: 1.74
    Marker Score: 16572
  • Cell Name: neuron associated cell (sensu Vertebrata) (CL0000123)
    Fold Change: 1.66
    Marker Score: 8713
  • Cell Name: plasma cell (CL0000786)
    Fold Change: 1.65
    Marker Score: 1840.5
  • Cell Name: OFF retinal ganglion cell (CL4023033)
    Fold Change: 1.64
    Marker Score: 689
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 1.61
    Marker Score: 621
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.61
    Marker Score: 1169
  • Cell Name: pyramidal neuron (CL0000598)
    Fold Change: 1.56
    Marker Score: 2619
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: 1.55
    Marker Score: 2389
  • Cell Name: chromaffin cell (CL0000166)
    Fold Change: 1.55
    Marker Score: 2175
  • Cell Name: inhibitory motor neuron (CL0008015)
    Fold Change: 1.53
    Marker Score: 724
  • Cell Name: cerebellar granule cell precursor (CL0002362)
    Fold Change: 1.52
    Marker Score: 854
  • Cell Name: acinar cell (CL0000622)
    Fold Change: 1.51
    Marker Score: 1064
  • Cell Name: rod bipolar cell (CL0000751)
    Fold Change: 1.49
    Marker Score: 776
  • Cell Name: kidney proximal convoluted tubule epithelial cell (CL1000838)
    Fold Change: 1.48
    Marker Score: 3069
  • Cell Name: mature astrocyte (CL0002627)
    Fold Change: 1.42
    Marker Score: 932
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 1.39
    Marker Score: 5814
  • Cell Name: granulocyte monocyte progenitor cell (CL0000557)
    Fold Change: 1.37
    Marker Score: 871
  • Cell Name: PP cell (CL0000696)
    Fold Change: 1.36
    Marker Score: 306
  • Cell Name: P/D1 enteroendocrine cell (CL0002268)
    Fold Change: 1.34
    Marker Score: 500
  • Cell Name: A2 amacrine cell (CL0004219)
    Fold Change: 1.34
    Marker Score: 425
  • Cell Name: granule cell (CL0000120)
    Fold Change: 1.28
    Marker Score: 9618
  • Cell Name: stellate neuron (CL0000122)
    Fold Change: 1.26
    Marker Score: 6757.5
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 1.26
    Marker Score: 374
  • Cell Name: macroglial cell (CL0000126)
    Fold Change: 1.22
    Marker Score: 2810.5
  • Cell Name: motor neuron (CL0000100)
    Fold Change: 1.22
    Marker Score: 722
  • Cell Name: ON retinal ganglion cell (CL4023032)
    Fold Change: 1.21
    Marker Score: 331
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 1.2
    Marker Score: 3420
  • Cell Name: CNS interneuron (CL0000402)
    Fold Change: 1.19
    Marker Score: 574
  • Cell Name: neuroblast (sensu Vertebrata) (CL0000031)
    Fold Change: 1.18
    Marker Score: 740
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 1.15
    Marker Score: 4809.5
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 1.07
    Marker Score: 444
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: 1.06
    Marker Score: 2159
  • Cell Name: sympathetic neuron (CL0011103)
    Fold Change: 1.05
    Marker Score: 348
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: 1.04
    Marker Score: 797
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: 1.04
    Marker Score: 2486
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: 1.04
    Marker Score: 251792
  • Cell Name: goblet cell (CL0000160)
    Fold Change: 1.03
    Marker Score: 6841
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.03
    Marker Score: 16081
  • Cell Name: type G enteroendocrine cell (CL0000508)
    Fold Change: 1.01
    Marker Score: 349
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: 1
    Marker Score: 71810
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: 1
    Marker Score: 48036
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 1
    Marker Score: 458
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.99
    Marker Score: 511
  • Cell Name: neuronal brush cell (CL0000555)
    Fold Change: 0.99
    Marker Score: 3315
  • Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
    Fold Change: 0.98
    Marker Score: 464
  • Cell Name: absorptive cell (CL0000212)
    Fold Change: 0.98
    Marker Score: 30407
  • Cell Name: astrocyte (CL0000127)
    Fold Change: 0.97
    Marker Score: 841
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.95
    Marker Score: 2412
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: 0.95
    Marker Score: 3956
  • Cell Name: enteroendocrine cell (CL0000164)
    Fold Change: 0.94
    Marker Score: 489
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.94
    Marker Score: 376
  • Cell Name: transit amplifying cell (CL0009010)
    Fold Change: 0.94
    Marker Score: 5349
  • Cell Name: neural crest cell (CL0011012)
    Fold Change: 0.93
    Marker Score: 996.5
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: 0.93
    Marker Score: 295
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: 0.92
    Marker Score: 2638
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.92
    Marker Score: 1239
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.92
    Marker Score: 2743
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.91
    Marker Score: 328
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: 0.9
    Marker Score: 539
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.89
    Marker Score: 261
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.87
    Marker Score: 5287
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 0.84
    Marker Score: 286
  • Cell Name: Mueller cell (CL0000636)
    Fold Change: 0.8
    Marker Score: 1105
  • Cell Name: migratory enteric neural crest cell (CL0002607)
    Fold Change: 0.79
    Marker Score: 741
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.78
    Marker Score: 1262
  • Cell Name: brush cell (CL0002204)
    Fold Change: 0.78
    Marker Score: 709
  • Cell Name: Cajal-Retzius cell (CL0000695)
    Fold Change: 0.77
    Marker Score: 399
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: 0.77
    Marker Score: 958
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.73
    Marker Score: 7368.5
  • Cell Name: Sertoli cell (CL0000216)
    Fold Change: 0.73
    Marker Score: 4304.5
  • Cell Name: cortical thymic epithelial cell (CL0002364)
    Fold Change: 0.72
    Marker Score: 2666
  • Cell Name: retina horizontal cell (CL0000745)
    Fold Change: 0.7
    Marker Score: 675
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.7
    Marker Score: 180

Hover over a box to see details here...

Hover over a box to see details here...

Hover over a box to see details here...

Other Information

**Key characteristics:** - KIF1A is a large protein with a molecular weight of approximately 130 kDa. - It is a microtubule-associated protein that is involved in various cellular processes, including anterograde axonal transport. - KIF1A is a key regulator of dendritic spine development and axonal transport. **Pathways and functions:** - KIF1A is involved in the anterograde axonal transport of vesicles and organelles within neurons. - It is a key regulator of dendritic spine development, ensuring the correct positioning of synaptic vesicles at the presynaptic terminal. - It also plays a role in axonal transport, transporting vesicles and organelles to their appropriate destinations within the neuron. **Clinical significance:** - Mutations in KIF1A have been linked to several neurodevelopmental disorders, including autism spectrum disorder, schizophrenia, and epilepsy. - These disorders are characterized by problems with brain development and function, which are likely caused by defects in axonal transport. - Targeting KIF1A could be a potential therapeutic strategy for these disorders. **Additional notes:** - KIF1A is a highly conserved protein with homologs in other species. - It is a regulated protein that is expressed in a cell-type-specific manner. - It is a key player in neuronal development and function.

Genular Protein ID: 2608053695

Symbol: KIF1A_HUMAN

Name: Kinesin-like protein KIF1A

UniProtKB Accession Codes:

Q12756 B0I1S5 F5H045 O95068 Q13355 Q14752 Q2NKJ6 Q4LE42 Q53T78 Q59GH1 Q63Z40 Q6P1R9 Q7KZ57

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 3 CTD 1 ChEBI 1 ChEMBL 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 2 EMBL 14 EPD 1 Ensembl 4 ExpressionAtlas 1 GO 24 Gene3D 4 GeneCards 1 GeneReviews 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 11 KEGG 1 MANE-Select 1 MIM 7 MINT 1 MalaCards 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 4 OrthoDB 1 PANTHER 2 PDB 8 PDBsum 6 PRINTS 1 PRO 1 PROSITE 4 PROSITE-ProRule 3 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 6 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 Pumba 1 RNAct 1 Reactome 2 RefSeq 4 SAM 1 SIGNOR 1 SMART 3 SMR 1 STRING 1 SUPFAM 3 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 UniProtKB 2 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8661001

Title: Characterization of a kinesin-related gene ATSV, within the tuberous sclerosis locus (TSC1) candidate region on chromosome 9q34.

PubMed ID: 8661001

DOI: 10.1006/geno.1996.0217

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 21820098

Title: KIF1A, an axonal transporter of synaptic vesicles, is mutated in hereditary sensory and autonomic neuropathy type 2.

PubMed ID: 21820098

DOI: 10.1016/j.ajhg.2011.06.013

PubMed ID: 21376300

Title: Excess of de novo deleterious mutations in genes associated with glutamatergic systems in nonsyndromic intellectual disability.

PubMed ID: 21376300

DOI: 10.1016/j.ajhg.2011.02.001

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 30021165

Title: Regulation of KIF1A-Driven Dense Core Vesicle Transport: Ca2+/CaM Controls DCV Binding and Liprin-alpha/TANC2 Recruits DCVs to Postsynaptic Sites.

PubMed ID: 30021165

DOI: 10.1016/j.celrep.2018.06.071

PubMed ID: 25585697

Title: Dominant transmission of de novo KIF1A motor domain variant underlying pure spastic paraplegia.

PubMed ID: 25585697

DOI: 10.1038/ejhg.2014.297

PubMed ID: 26410750

Title: Variants in KIF1A gene in dominant and sporadic forms of hereditary spastic paraparesis.

PubMed ID: 26410750

DOI: 10.1007/s00415-015-7899-9

PubMed ID: 21487076

Title: Exome sequencing and disease-network analysis of a single family implicate a mutation in KIF1A in hereditary spastic paraparesis.

PubMed ID: 21487076

DOI: 10.1101/gr.117143.110

PubMed ID: 22258533

Title: KIF1A missense mutations in SPG30, an autosomal recessive spastic paraplegia: distinct phenotypes according to the nature of the mutations.

PubMed ID: 22258533

DOI: 10.1038/ejhg.2011.261

PubMed ID: 25253658

Title: KIF1A mutation in a patient with progressive neurodegeneration.

PubMed ID: 25253658

DOI: 10.1038/jhg.2014.80

PubMed ID: 26125038

Title: De novo mutations in KIF1A cause progressive encephalopathy and brain atrophy.

PubMed ID: 26125038

DOI: 10.1002/acn3.198

PubMed ID: 26354034

Title: De novo KIF1A mutations cause intellectual deficit, cerebellar atrophy, lower limb spasticity and visual disturbance.

PubMed ID: 26354034

DOI: 10.1038/jhg.2015.108

PubMed ID: 25265257

Title: De novo mutations in the motor domain of KIF1A cause cognitive impairment, spastic paraparesis, axonal neuropathy, and cerebellar atrophy.

PubMed ID: 25265257

DOI: 10.1002/humu.22709

PubMed ID: 26486474

Title: De novo dominant variants affecting the motor domain of KIF1A are a cause of PEHO syndrome.

PubMed ID: 26486474

DOI: 10.1038/ejhg.2015.217

PubMed ID: 27034427

Title: Novel De Novo Mutations in KIF1A as a Cause of Hereditary Spastic Paraplegia With Progressive Central Nervous System Involvement.

PubMed ID: 27034427

DOI: 10.1177/0883073816639718

PubMed ID: 29159194

Title: Multigeneration family with dominant SPG30 hereditary spastic paraplegia.

PubMed ID: 29159194

DOI: 10.1002/acn3.452

PubMed ID: 28832565

Title: Massive sequencing of 70 genes reveals a myriad of missing genes or mechanisms to be uncovered in hereditary spastic paraplegias.

PubMed ID: 28832565

DOI: 10.1038/ejhg.2017.124

PubMed ID: 28834584

Title: A de novo dominant mutation in KIF1A associated with axonal neuropathy, spasticity and autism spectrum disorder.

PubMed ID: 28834584

DOI: 10.1111/jns.12235

PubMed ID: 29934652

Title: Targeted next-generation sequencing improves diagnosis of hereditary spastic paraplegia in Chinese patients.

PubMed ID: 29934652

DOI: 10.1007/s00109-018-1655-4

PubMed ID: 31796088

Title: Long-term follow-up until early adulthood in autosomal dominant, complex SPG30 with a novel KIF1A variant: a case report.

PubMed ID: 31796088

DOI: 10.1186/s13052-019-0752-5

PubMed ID: 31488895

Title: KIF1A variants are a frequent cause of autosomal dominant hereditary spastic paraplegia.

PubMed ID: 31488895

DOI: 10.1038/s41431-019-0497-z

PubMed ID: 32652677

Title: Expansion of the phenotypic spectrum of de novo missense variants in kinesin family member 1A (KIF1A).

PubMed ID: 32652677

DOI: 10.1002/humu.24079

PubMed ID: 32096284

Title: KIF1A-related disorders in children: A wide spectrum of central and peripheral nervous system involvement.

PubMed ID: 32096284

DOI: 10.1111/jns.12368

PubMed ID: 31805580

Title: Mobility characteristics of children with spastic paraplegia due to a mutation in the KIF1A gene.

PubMed ID: 31805580

DOI: 10.1055/s-0039-3400988

PubMed ID: 33880452

Title: Genotype and defects in microtubule-based motility correlate with clinical severity in KIF1A-associated neurological disorder.

PubMed ID: 33880452

DOI: 10.1016/j.xhgg.2021.100026

Sequence Information:

  • Length: 1690
  • Mass: 191064
  • Checksum: FB3CA33B7060AF60
  • Sequence:
    • MAGASVKVAV RVRPFNSREM SRDSKCIIQM SGSTTTIVNP KQPKETPKSF SFDYSYWSHT 
SPEDINYASQ KQVYRDIGEE MLQHAFEGYN VCIFAYGQTG AGKSYTMMGK QEKDQQGIIP 
QLCEDLFSRI NDTTNDNMSY SVEVSYMEIY CERVRDLLNP KNKGNLRVRE HPLLGPYVED 
LSKLAVTSYN DIQDLMDSGN KARTVAATNM NETSSRSHAV FNIIFTQKRH DAETNITTEK 
VSKISLVDLA GSERADSTGA KGTRLKEGAN INKSLTTLGK VISALAEMDS GPNKNKKKKK 
TDFIPYRDSV LTWLLRENLG GNSRTAMVAA LSPADINYDE TLSTLRYADR AKQIRCNAVI 
NEDPNNKLIR ELKDEVTRLR DLLYAQGLGD ITDMTNALVG MSPSSSLSAL SSRAASVSSL 
HERILFAPGS EEAIERLKET EKIIAELNET WEEKLRRTEA IRMEREALLA EMGVAMREDG 
GTLGVFSPKK TPHLVNLNED PLMSECLLYY IKDGITRVGR EDGERRQDIV LSGHFIKEEH 
CVFRSDSRGG SEAVVTLEPC EGADTYVNGK KVTEPSILRS GNRIIMGKSH VFRFNHPEQA 
RQERERTPCA ETPAEPVDWA FAQRELLEKQ GIDMKQEMEQ RLQELEDQYR REREEATYLL 
EQQRLDYESK LEALQKQMDS RYYPEVNEEE EEPEDEVQWT ERECELALWA FRKWKWYQFT 
SLRDLLWGNA IFLKEANAIS VELKKKVQFQ FVLLTDTLYS PLPPDLLPPE AAKDRETRPF 
PRTIVAVEVQ DQKNGATHYW TLEKLRQRLD LMREMYDRAA EVPSSVIEDC DNVVTGGDPF 
YDRFPWFRLV GRAFVYLSNL LYPVPLVHRV AIVSEKGEVK GFLRVAVQAI SADEEAPDYG 
SGVRQSGTAK ISFDDQHFEK FQSESCPVVG MSRSGTSQEE LRIVEGQGQG ADVGPSADEV 
NNNTCSAVPP EGLLLDSSEK AALDGPLDAA LDHLRLGNTF TFRVTVLQAS SISAEYADIF 
CQFNFIHRHD EAFSTEPLKN TGRGPPLGFY HVQNIAVEVT KSFIEYIKSQ PIVFEVFGHY 
QQHPFPPLCK DVLSPLRPSR RHFPRVMPLS KPVPATKLST LTRPCPGPCH CKYDLLVYFE 
ICELEANGDY IPAVVDHRGG MPCMGTFLLH QGIQRRITVT LLHETGSHIR WKEVRELVVG 
RIRNTPETDE SLIDPNILSL NILSSGYIHP AQDDRTFYQF EAAWDSSMHN SLLLNRVTPY 
REKIYMTLSA YIEMENCTQP AVVTKDFCMV FYSRDAKLPA SRSIRNLFGS GSLRASESNR 
VTGVYELSLC HVADAGSPGM QRRRRRVLDT SVAYVRGEEN LAGWRPRSDS LILDHQWELE 
KLSLLQEVEK TRHYLLLREK LETAQRPVPE ALSPAFSEDS ESHGSSSASS PLSAEGRPSP 
LEAPNERQRE LAVKCLRLLT HTFNREYTHS HVCVSASESK LSEMSVTLLR DPSMSPLGVA 
TLTPSSTCPS LVEGRYGATD LRTPQPCSRP ASPEPELLPE ADSKKLPSPA RATETDKEPQ 
RLLVPDIQEI RVSPIVSKKG YLHFLEPHTS GWARRFVVVR RPYAYMYNSD KDTVERFVLN 
LATAQVEYSE DQQAMLKTPN TFAVCTEHRG ILLQAASDKD MHDWLYAFNP LLAGTIRSKL 
SRRRSAQMRV

Genular Protein ID: 2508115858

Symbol: A0A3B3IU40_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A3B3IU40

Database IDs:

ARBA 7 Antibodypedia 1 Bgee 1 CDD 3 CTD 1 ChEBI 1 ChiTaRS 1 DNASU 1 EMBL 2 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 7 Gene3D 4 GeneTree 1 HGNC 1 InterPro 11 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 7 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 6 Proteomes 2 RefSeq 1 SAM 2 SMART 3 SMR 1 SUPFAM 3 VEuPathDB 1

Citations:

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

Sequence Information:

  • Length: 1699
  • Mass: 191898
  • Checksum: D1FE33C15470BDA8
  • Sequence:
    • MAGASVKVAV RVRPFNSREM SRDSKCIIQM SGSTTTIVNP KQPKETPKSF SFDYSYWSHT 
SPEDINYASQ KQVYRDIGEE MLQHAFEGYN VCIFAYGQTG AGKSYTMMGK QEKDQQGIIP 
QLCEDLFSRI NDTTNDNMSY SVEVSYMEIY CERVRDLLNP KNKGNLRVRE HPLLGPYVED 
LSKLAVTSYN DIQDLMDSGN KARTVAATNM NETSSRSHAV FNIIFTQKRH DAETNITTEK 
VSKISLVDLA GSERADSTGA KGTRLKEGAN INKSLTTLGK VISALAEMDS GPNKNKKKKK 
TDFIPYRDSV LTWLLRENLG GNSRTAMVAA LSPADINYDE TLSTLRYADR AKQIRCNAVI 
NEDPNNKLIR ELKDEVTRLR DLLYAQGLGD ITDTNTVPGG PKLTNALVGM SPSSSLSALS 
SRAASVSSLH ERILFAPGSE EAIERLKETE KIIAELNETW EEKLRRTEAI RMEREALLAE 
MGVAMREDGG TLGVFSPKKT PHLVNLNEDP LMSECLLYYI KDGITRVGRE DGERRQDIVL 
SGHFIKEEHC VFRSDSRGGS EAVVTLEPCE GADTYVNGKK VTEPSILRSG NRIIMGKSHV 
FRFNHPEQAR QERERTPCAE TPAEPVDWAF AQRELLEKQG IDMKQEMEQR LQELEDQYRR 
EREEATYLLE QQRLDYESKL EALQKQMDSR YYPEVNEEEE EPEDEVQWTE RECELALWAF 
RKWKWYQFTS LRDLLWGNAI FLKEANAISV ELKKKVQFQF VLLTDTLYSP LPPDLLPPEA 
AKDRETRPFP RTIVAVEVQD QKNGATHYWT LEKLRQRLDL MREMYDRAAE VPSSVIEDCD 
NVVTGGDPFY DRFPWFRLVG RAFVYLSNLL YPVPLVHRVA IVSEKGEVKG FLRVAVQAIS 
ADEEAPDYGS GVRQSGTAKI SFDDQHFEKF QSESCPVVGM SRSGTSQEEL RIVEGQGQGA 
DVGPSADEVN NNTCSAVPPE GLLLDSSEKA ALDGPLDAAL DHLRLGNTFT FRVTVLQASS 
ISAEYADIFC QFNFIHRHDE AFSTEPLKNT GRGPPLGFYH VQNIAVEVTK SFIEYIKSQP 
IVFEVFGHYQ QHPFPPLCKD VLSPLRPSRR HFPRVMPLSK PVPATKLSTL TRPCPGPCHC 
KYDLLVYFEI CELEANGDYI PAVVDHRGGM PCMGTFLLHQ GIQRRITVTL LHETGSHIRW 
KEVRELVVGR IRNTPETDES LIDPNILSLN ILSSGYIHPA QDDRTFYQFE AAWDSSMHNS 
LLLNRVTPYR EKIYMTLSAY IEMENCTQPA VVTKDFCMVF YSRDAKLPAS RSIRNLFGSG 
SLRASESNRV TGVYELSLCH VADAGSPGMQ RRRRRVLDTS VAYVRGEENL AGWRPRSDSL 
ILDHQWELEK LSLLQEVEKT RHYLLLREKL ETAQRPVPEA LSPAFSEDSE SHGSSSASSP 
LSAEGRPSPL EAPNERQREL AVKCLRLLTH TFNREYTHSH VCVSASESKL SEMSVTLLRD 
PSMSPLGVAT LTPSSTCPSL VEGRYGATDL RTPQPCSRPA SPEPELLPEA DSKKLPSPAR 
ATETDKEPQR LLVPDIQEIR VSPIVSKKGY LHFLEPHTSG WARRFVVVRR PYAYMYNSDK 
DTVERFVLNL ATAQVEYSED QQAMLKTPNT FAVCTEHRGI LLQAASDKDM HDWLYAFNPL 
LAGTIRSKLS RRRSAQMRV

Genular Protein ID: 432755203

Symbol: A0A3B3IT28_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A3B3IT28

Database IDs:

ARBA 7 Antibodypedia 1 Bgee 1 CDD 3 CTD 1 ChEBI 1 ChiTaRS 1 DNASU 1 EMBL 2 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 7 Gene3D 4 GeneTree 1 HGNC 1 InterPro 11 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 7 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 6 Proteomes 2 RefSeq 1 SAM 2 SMART 3 SMR 1 SUPFAM 3 VEuPathDB 1

Citations:

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

Sequence Information:

  • Length: 1708
  • Mass: 192970
  • Checksum: 1704D8FC2783AD21
  • Sequence:
    • MAGASVKVAV RVRPFNSREM SRDSKCIIQM SGSTTTIVNP KQPKETPKSF SFDYSYWSHT 
SPEDINYASQ KQVYRDIGEE MLQHAFEGYN VCIFAYGQTG AGKSYTMMGK QEKDQQGIIP 
QLCEDLFSRI NDTTNDNMSY SVEVSYMEIY CERVRDLLNP KNKGNLRVRE HPLLGPYVED 
LSKLAVTSYN DIQDLMDSGN KARTVAATNM NETSSRSHAV FNIIFTQKRH DAETNITTEK 
VSKISLVDLA GSERADSTGA KGTRLKEGAN INKSLTTLGK VISALAEMDS GPNKNKKKKK 
TDFIPYRDSV LTWLLRENLG GNSRTAMVAA LSPADINYDE TLSTLRYADR AKQIRCNAVI 
NEDPNNKLIR ELKDEVTRLR DLLYAQGLGD ITDTNTVPGG PKLTNALVGM SPSSSLSALS 
SRAASVSSLH ERILFAPGSE EAIERLKETE KIIAELNETW EEKLRRTEAI RMEREALLAE 
MGVAMREDGG TLGVFSPKKT PHLVNLNEDP LMSECLLYYI KDGITRVGRE DGERRQDIVL 
SGHFIKEEHC VFRSDSRGGS EAVVTLEPCE GADTYVNGKK VTEPSILRSG NRIIMGKSHV 
FRFNHPEQAR QERERTPCAE TPAEPVDWAF AQRELLEKQG IDMKQEMEQR LQELEDQYRR 
EREEATYLLE QQRLDYESKL EALQKQMDSR YYPEVNEEEE EPEDEVQWTE RECELALWAF 
RKWKWYQFTS LRDLLWGNAI FLKEANAISV ELKKKVQFQF VLLTDTLYSP LPPDLLPPEA 
AKDRETRPFP RTIVAVEVQD QKNGATHYWT LEKLRQRLDL MREMYDRAAE VPSSVIEDCD 
NVVTGGDPFY DRFPWFRLVG RAFVYLSNLL YPVPLVHRVA IVSEKGEVKG FLRVAVQAIS 
ADEEAPDYGS GVRQSGTAKI SFDDQHFEKF QSESCPVVGM SRSGTSQEEL RIVEGQGQGA 
DVGPSADEVN NNTCSAVPPE GLLLDSSEKA ALDGPLDAAL DHLRLGNTFT FRVTVLQASS 
ISAEYADIFC QFNFIHRHDE AFSTEPLKNT GRGPPLGFYH VQNIAVEVTK SFIEYIKSQP 
IVFEVFGHYQ QHPFPPLCKD VLSPLRPSRR HFPRVMPLSK PVPATKLSTL TRPCPGPCHC 
KYDLLVYFEI CELEANGDYI PAVVDHRGGM PCMGTFLLHQ GIQRRITVTL LHETGSHIRW 
KEVRELVVGR IRNTPETDES LIDPNILSLN ILSSGYIHPA QDDRQFLDSD IPRTFYQFEA 
AWDSSMHNSL LLNRVTPYRE KIYMTLSAYI EMENCTQPAV VTKDFCMVFY SRDAKLPASR 
SIRNLFGSGS LRASESNRVT GVYELSLCHV ADAGSPGMQR RRRRVLDTSV AYVRGEENLA 
GWRPRSDSLI LDHQWELEKL SLLQEVEKTR HYLLLREKLE TAQRPVPEAL SPAFSEDSES 
HGSSSASSPL SAEGRPSPLE APNERQRELA VKCLRLLTHT FNREYTHSHV CVSASESKLS 
EMSVTLLRDP SMSPLGVATL TPSSTCPSLV EGRYGATDLR TPQPCSRPAS PEPELLPEAD 
SKKLPSPARA TETDKEPQRL LVPDIQEIRV SPIVSKKGYL HFLEPHTSGW ARRFVVVRRP 
YAYMYNSDKD TVERFVLNLA TAQVEYSEDQ QAMLKTPNTF AVCTEHRGIL LQAASDKDMH 
DWLYAFNPLL AGTIRSKLSR RRSAQMRV

Genular Protein ID: 1111105731

Symbol: A0A3B3ITE5_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A3B3ITE5

Database IDs:

ARBA 7 Antibodypedia 1 Bgee 1 CDD 3 CTD 1 ChEBI 1 ChiTaRS 1 DNASU 1 EMBL 2 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 7 Gene3D 4 GeneTree 1 HGNC 1 InterPro 11 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 7 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 6 Proteomes 2 RefSeq 1 SAM 2 SMART 3 SMR 1 SUPFAM 3 VEuPathDB 1

Citations:

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

Sequence Information:

  • Length: 1724
  • Mass: 194556
  • Checksum: 038AE5CE2C4B2BFE
  • Sequence:
    • MAGASVKVAV RVRPFNSREM SRDSKCIIQM SGSTTTIVNP KQPKETPKSF SFDYSYWSHT 
SPEDINYASQ KQVYRDIGEE MLQHAFEGYN VCIFAYGQTG AGKSYTMMGK QEKDQQGIIP 
QLCEDLFSRI NDTTNDNMSY SVEVSYMEIY CERVRDLLNP KNKGNLRVRE HPLLGPYVED 
LSKLAVTSYN DIQDLMDSGN KARTVAATNM NETSSRSHAV FNIIFTQKRH DAETNITTEK 
VSKISLVDLA GSERADSTGA KGTRLKEGAN INKSLTTLGK VISALAEMDS GPNKNKKKKK 
TDFIPYRDSV LTWLLRENLG GNSRTAMVAA LSPADINYDE TLSTLRYADR AKQIRCNAVI 
NEDPNNKLIR ELKDEVTRLR DLLYAQGLGD ITDTNTVPGG PKYVSDLENN NLNRGGTVNE 
APDPLSTVTN ALVGMSPSSS LSALSSRAAS VSSLHERILF APGSEEAIER LKETEKIIAE 
LNETWEEKLR RTEAIRMERE ALLAEMGVAM REDGGTLGVF SPKKTPHLVN LNEDPLMSEC 
LLYYIKDGIT RVGREDGERR QDIVLSGHFI KEEHCVFRSD SRGGSEAVVT LEPCEGADTY 
VNGKKVTEPS ILRSGNRIIM GKSHVFRFNH PEQARQERER TPCAETPAEP VDWAFAQREL 
LEKQGIDMKQ EMEQRLQELE DQYRREREEA TYLLEQQRLD YESKLEALQK QMDSRYYPEV 
NEEEEEPEDE VQWTERECEL ALWAFRKWKW YQFTSLRDLL WGNAIFLKEA NAISVELKKK 
VQFQFVLLTD TLYSPLPPDL LPPEAAKDRE TRPFPRTIVA VEVQDQKNGA THYWTLEKLR 
QRLDLMREMY DRAAEVPSSV IEDCDNVVTG GDPFYDRFPW FRLVGRAFVY LSNLLYPVPL 
VHRVAIVSEK GEVKGFLRVA VQAISADEEA PDYGSGVRQS GTAKISFDDQ HFEKFQSESC 
PVVGMSRSGT SQEELRIVEG QGQGADVGPS ADEVNNNTCS AVPPEGLLLD SSEKAALDGP 
LDAALDHLRL GNTFTFRVTV LQASSISAEY ADIFCQFNFI HRHDEAFSTE PLKNTGRGPP 
LGFYHVQNIA VEVTKSFIEY IKSQPIVFEV FGHYQQHPFP PLCKDVLSPL RPSRRHFPRV 
MPLSKPVPAT KLSTLTRPCP GPCHCKYDLL VYFEICELEA NGDYIPAVVD HRGGMPCMGT 
FLLHQGIQRR ITVTLLHETG SHIRWKEVRE LVVGRIRNTP ETDESLIDPN ILSLNILSSG 
YIHPAQDDRT FYQFEAAWDS SMHNSLLLNR VTPYREKIYM TLSAYIEMEN CTQPAVVTKD 
FCMVFYSRDA KLPASRSIRN LFGSGSLRAS ESNRVTGVYE LSLCHVADAG SPGMQRRRRR 
VLDTSVAYVR GEENLAGWRP RSDSLILDHQ WELEKLSLLQ EVEKTRHYLL LREKLETAQR 
PVPEALSPAF SEDSESHGSS SASSPLSAEG RPSPLEAPNE RQRELAVKCL RLLTHTFNRE 
YTHSHVCVSA SESKLSEMSV TLLRDPSMSP LGVATLTPSS TCPSLVEGRY GATDLRTPQP 
CSRPASPEPE LLPEADSKKL PSPARATETD KEPQRLLVPD IQEIRVSPIV SKKGYLHFLE 
PHTSGWARRF VVVRRPYAYM YNSDKDTVER FVLNLATAQV EYSEDQQAML KTPNTFAVCT 
EHRGILLQAA SDKDMHDWLY AFNPLLAGTI RSKLSRRRSA QMRV

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.