Details for: Egln3

Gene ID: 54702

Symbol: Egln3

Ensembl ID: ENSRNOG00000005053

Description: egl-9 family hypoxia-inducible factor 3

Associated with

Other Information

Genular Protein ID: 2745129289

Symbol: EGLN3_RAT

Name: Egl nine homolog 3

UniProtKB Accession Codes:

Q62630

Database IDs:

AGR 1 AlphaFoldDB 1 BioGRID 1 CTD 1 ChEBI 18 EC 1 EMBL 1 GO 16 Gene3D 1 InParanoid 1 InterPro 3 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIR 1 PRO 1 PROSITE 1 PROSITE-ProRule 1 PaxDb 1 Pfam 1 PhosphoSitePlus 1 Proteomes 1 RGD 1 Reactome 1 RefSeq 1 Rhea 7 SMART 1 SMR 1 STRING 1 UCSC 1 UniProtKB 4 eggNOG 1

Citations:

PubMed ID: 8175725

Title: Identification of a novel growth factor-responsive gene in vascular smooth muscle cells.

PubMed ID: 8175725

DOI: 10.1016/s0021-9258(18)99981-3

PubMed ID: 10386996

Title: Expression of the SM-20 gene promotes death in nerve growth factor-dependent sympathetic neurons.

PubMed ID: 10386996

DOI: 10.1046/j.1471-4159.1999.0730429.x

PubMed ID: 11595184

Title: C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation.

PubMed ID: 11595184

DOI: 10.1016/s0092-8674(01)00507-4

PubMed ID: 11060309

Title: SM-20 is a novel mitochondrial protein that causes caspase-dependent cell death in nerve growth factor-dependent neurons.

PubMed ID: 11060309

DOI: 10.1074/jbc.m008407200

PubMed ID: 15081411

Title: Regulation of the SM-20 prolyl hydroxylase gene in smooth muscle cells.

PubMed ID: 15081411

DOI: 10.1016/j.bbrc.2004.03.115

PubMed ID: 16407229

Title: The novel WD-repeat protein Morg1 acts as a molecular scaffold for hypoxia-inducible factor prolyl hydroxylase 3 (PHD3).

PubMed ID: 16407229

DOI: 10.1074/jbc.m513751200

PubMed ID: 16765982

Title: HIF prolyl hydroxylases in the rat; organ distribution and changes in expression following hypoxia and coronary artery ligation.

PubMed ID: 16765982

DOI: 10.1016/j.yjmcc.2006.04.009

PubMed ID: 20849813

Title: Prolyl hydroxylase 3 interacts with Bcl-2 to regulate doxorubicin-induced apoptosis in H9c2 cells.

PubMed ID: 20849813

DOI: 10.1016/j.bbrc.2010.09.037

Sequence Information:

  • Length: 239
  • Mass: 27242
  • Checksum: F410274976499755
  • Sequence:
    • MPLGHIMRLD LEKIALEYIV PCLHEVGFCY LDNFLGEVVG DCVLERVKQL HYNGALRDGQ 
LAGPRAGVSK RHLRGDQITW IGGNEEGCEA INFLLSLIDR LVLYCGSRLG KYYVKERSKA 
MVACYPGNGT GYVRHVDNPN GDGRCITCIY YLNKNWDAKL HGGVLRIFPE GKSFVADVEP 
IFDRLLFSWS DRRNPHEVQP SYATRYAMTV WYFDAEERAE AKKKFRNLTR KTESALAKD

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.