Rcan1 | ENSMUSG00000022951 | NCBI 54720

Details for: Rcan1

Gene ID: 54720

Symbol: Rcan1

Ensembl ID: ENSMUSG00000022951

Description: regulator of calcineurin 1

Associated with

Calcineurin-nfat signaling cascade
(GO:0033173)
Calcium-dependent protein serine/threonine phosphatase regulator activity
(GO:0008597)
Calcium-mediated signaling
(GO:0019722)
Cytoplasm
(GO:0005737)
Identical protein binding
(GO:0042802)
Locomotion involved in locomotory behavior
(GO:0031987)
Negative regulation of calcineurin-nfat signaling cascade
(GO:0070885)
Negative regulation of smooth muscle cell differentiation
(GO:0051151)
Nucleic acid binding
(GO:0003676)
Nucleus
(GO:0005634)
Protein binding
(GO:0005515)
Regulation of phosphoprotein phosphatase activity
(GO:0043666)
Response to estrogen
(GO:0043627)
Response to ischemia
(GO:0002931)
Response to oxidative stress
(GO:0006979)
Response to stress
(GO:0006950)
Short-term memory
(GO:0007614)
Skeletal muscle fiber development
(GO:0048741)

Other Information

Proteins

Calcipressin-1
Q542V6_MOUSE

Genular Protein ID: 1410932091

Symbol: RCAN1_MOUSE

Name: Calcipressin-1

UniProtKB Accession Codes:

Q9JHG6 Q7TNY3 Q91WQ4 Q9JK50 Q9JK51 Q9JKK2 Q9JKK3

Database IDs:

Citations:

PubMed ID: 10722714

Title: A protein encoded within the Down syndrome critical region is enriched in striated muscles and inhibits calcineurin signaling.

PubMed ID: 10722714

DOI: 10.1074/jbc.275.12.8719

PubMed ID: 11231093

Title: Dscr1, a novel endogenous inhibitor of calcineurin signaling, is expressed in the primitive ventricle of the heart and during neurogenesis.

PubMed ID: 11231093

DOI: 10.1016/s0925-4773(00)00583-9

PubMed ID: 12809556

Title: Phosphorylation of calcipressin 1 increases its ability to inhibit calcineurin and decreases calcipressin half-life.

PubMed ID: 12809556

DOI: 10.1042/bj20030267

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11080588

Title: The murine DSCR1-like (Down syndrome candidate region 1) gene family: conserved synteny with the human orthologous genes.

PubMed ID: 11080588

DOI: 10.1016/s0378-1119(00)00407-8

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 251
Mass: 28137
Checksum: 09F47C73D847FB2B
Sequence:

MEDGVAGPRL GEVAEAVEAR APRRVTLRPF APFSAAAEGD GGGGGDWSFI DCEMEEVDLQ 
DLPSATIACH LDPRVFVDGL CRAKFESLFR TYDKDTTFQY FKSFKRVRIN FSNPLSAADA 
RLRLHKTEFL GKEMKLYFAQ TLHIGSSHLA PPNPDKQFLI SPPASPPVGW KQVEDATPVI 
NYDLLYAISK LGPGEKYELH AATDTTPSVV VHVCESDQEN EEEEEEMERM KRPKPKIIQT 
RRPEYTPIHL S

Genular Protein ID: 802957320

Symbol: Q542V6_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q542V6

Database IDs:

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

Sequence Information:

Length: 198
Mass: 22851
Checksum: F017C68F18ACC187
Sequence:

MHFRDFSYNF SSLIACVAND DVFSESETRA KFESLFRTYD KDTTFQYFKS FKRVRINFSN 
PLSAADARLR LHKTEFLGKE MKLYFAQTLH IGSSHLAPPN PDKQFLISPP ASPPVGWKQV 
EDATPVINYD LLYAISKLGP GEKYELHAAT DTTPSVVVHV CESDQENEEE EEEMERMKRP 
KPKIIQTRRP EYTPIHLS

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Rcan1

Associated with

Other Information

A protein encoded within the Down syndrome critical region is enriched in striated muscles and inhibits calcineurin signaling. PubMed ID: 10722714

Dscr1, a novel endogenous inhibitor of calcineurin signaling, is expressed in the primitive ventricle of the heart and during neurogenesis. PubMed ID: 11231093

Phosphorylation of calcipressin 1 increases its ability to inhibit calcineurin and decreases calcipressin half-life. PubMed ID: 12809556

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

The murine DSCR1-like (Down syndrome candidate region 1) gene family: conserved synteny with the human orthologous genes. PubMed ID: 11080588

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

High-efficiency full-length cDNA cloning. PubMed ID: 10349636

Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. PubMed ID: 11042159

RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. PubMed ID: 11076861

Functional annotation of a full-length mouse cDNA collection. PubMed ID: 11217851

Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. PubMed ID: 12466851

Antisense Transcription in the Mammalian Transcriptome. PubMed ID: 16141073