Details for: FEV

Gene ID: 54738

Symbol: FEV

Ensembl ID: ENSG00000163497

Description: FEV transcription factor, ETS family member

Associated with

  • Cell differentiation
    (GO:0030154)
  • Chromatin
    (GO:0000785)
  • Dna-binding transcription activator activity, rna polymerase ii-specific
    (GO:0001228)
  • Dna-binding transcription factor activity, rna polymerase ii-specific
    (GO:0000981)
  • Maternal behavior
    (GO:0042711)
  • Neuron fate specification
    (GO:0048665)
  • Neuron maturation
    (GO:0042551)
  • Nuclear speck
    (GO:0016607)
  • Nucleus
    (GO:0005634)
  • Positive regulation of gene expression
    (GO:0010628)
  • Positive regulation of transcription by rna polymerase ii
    (GO:0045944)
  • Regulation of transcription by rna polymerase ii
    (GO:0006357)
  • Rna polymerase ii cis-regulatory region sequence-specific dna binding
    (GO:0000978)
  • Sequence-specific double-stranded dna binding
    (GO:1990837)

Other Information

Genular Protein ID: 737917621

Symbol: FEV_HUMAN

Name: Protein FEV

UniProtKB Accession Codes:

Q99581

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CTD 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 4 Ensembl 1 GO 12 Gene3D 1 GeneCards 1 GeneTree 1 Genevisible 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 3 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 3 PDBsum 2 PRINTS 1 PRO 1 PROSITE 3 PROSITE-ProRule 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 RefSeq 1 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 neXtProt 1

Citations:

PubMed ID: 9121764

Title: A new member of the ETS family fused to EWS in Ewing tumors.

PubMed ID: 9121764

DOI: 10.1038/sj.onc.1200933

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12761502

Title: FEV acts as a transcriptional repressor through its DNA-binding ETS domain and alanine-rich domain.

PubMed ID: 12761502

DOI: 10.1038/sj.onc.1206572

PubMed ID: 15003288

Title: The Ets transcription factor Fev is specifically expressed in the human central serotonergic neurons.

PubMed ID: 15003288

DOI: 10.1016/j.neulet.2003.12.086

PubMed ID: 15986391

Title: Regional distribution and cellular localization of the ETS-domain transcription factor, FEV, mRNA in the human postmortem brain.

PubMed ID: 15986391

DOI: 10.1002/syn.20178

PubMed ID: 17172842

Title: Expression of EWS-ETS fusions in NIH3T3 cells reveals significant differences to Ewing's sarcoma.

PubMed ID: 17172842

DOI: 10.4161/cc.5.23.3505

PubMed ID: 17597646

Title: Sudden infant death syndrome: rare mutation in the serotonin system FEV gene.

PubMed ID: 17597646

DOI: 10.1203/pdr.0b013e3180a725a0

Sequence Information:

  • Length: 238
  • Mass: 25030
  • Checksum: 057E4A76FBDD6E0A
  • Sequence:
    • MRQSGASQPL LINMYLPDPV GDGLFKDGKN PSWGPLSPAV QKGSGQIQLW QFLLELLADR 
ANAGCIAWEG GHGEFKLTDP DEVARRWGER KSKPNMNYDK LSRALRYYYD KNIMSKVHGK 
RYAYRFDFQG LAQACQPPPA HAHAAAAAAA AAAAAQDGAL YKLPAGLAPL PFPGLSKLNL 
MAASAGVAPA GFSYWPGPGP AATAAAATAA LYPSPSLQPP PGPFGAVAAA SHLGGHYH

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.