Details for: LEPROT

Gene ID: 54741

Symbol: LEPROT

Ensembl ID: ENSG00000213625

Description: leptin receptor overlapping transcript

Associated with

  • Endosome
    (GO:0005768)
  • Endosome membrane
    (GO:0010008)
  • Golgi apparatus
    (GO:0005794)
  • Golgi membrane
    (GO:0000139)
  • Late endosome to vacuole transport via multivesicular body sorting pathway
    (GO:0032511)
  • Negative regulation of growth hormone receptor signaling pathway
    (GO:0060400)
  • Negative regulation of protein localization to cell surface
    (GO:2000009)
  • Negative regulation of receptor signaling pathway via jak-stat
    (GO:0046426)
  • Positive regulation of protein targeting to mitochondrion
    (GO:1903955)
  • Protein binding
    (GO:0005515)
  • Signaling receptor binding
    (GO:0005102)

Other Information

Genular Protein ID: 1854156992

Symbol: OBRG_HUMAN

Name: Leptin receptor gene-related protein

UniProtKB Accession Codes:

O15243 Q6FHL5

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CTD 1 ChiTaRS 1 DIP 1 DNASU 1 DisGeNET 1 EMBL 9 EPD 1 Ensembl 1 ExpressionAtlas 1 GO 10 GeneCards 1 GeneTree 1 Genevisible 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 1 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 RefSeq 2 STRING 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9207021

Title: The leptin receptor promoter controls expression of a second distinct protein.

PubMed ID: 9207021

DOI: 10.1093/nar/25.14.2752

PubMed ID: 16303743

Title: Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.

PubMed ID: 16303743

DOI: 10.1093/dnares/12.2.117

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 18042720

Title: Silencing of OB-RGRP in mouse hypothalamic arcuate nucleus increases leptin receptor signaling and prevents diet-induced obesity.

PubMed ID: 18042720

DOI: 10.1073/pnas.0706671104

PubMed ID: 19907080

Title: LEPROT and LEPROTL1 cooperatively decrease hepatic growth hormone action in mice.

PubMed ID: 19907080

DOI: 10.1172/jci34997

Sequence Information:

  • Length: 131
  • Mass: 14254
  • Checksum: 0F9CE741C2C5ED9C
  • Sequence:
    • MAGVKALVAL SFSGAIGLTF LMLGCALEDY GVYWPLFVLI FHAISPIPHF IAKRVTYDSD 
ATSSACRELA YFFTTGIVVS AFGFPVILAR VAVIKWGACG LVLAGNAVIF LTIQGFFLIF 
GRGDDFSWEQ W

Genular Protein ID: 772835542

Symbol: A0A087X0N2_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A087X0N2

Database IDs:

ARBA 9 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 1 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 1 GeneTree 1 GenomeRNAi 1 HGNC 1 InterPro 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 1 PeptideAtlas 1 Pfam 1 Proteomes 2 RefSeq 1 SAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

Sequence Information:

  • Length: 140
  • Mass: 15428
  • Checksum: CAE48516F89F2A68
  • Sequence:
    • MRDGKGFLQG FLYFALVALS FSGAIGLTFL MLGCALEDYG VYWPLFVLIF HAISPIPHFI 
AKRVTYDSDA TSSACRELAY FFTTGIVVSA FGFPVILARV AVIKWGACGL VLAGNAVIFL 
TIQGFFLIFG RGDDFSWEQW

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.