ZRANB1 | ENSG00000019995 | NCBI 54764

Details for: ZRANB1

Gene ID: 54764

Symbol: ZRANB1

Ensembl ID: ENSG00000019995

Description: zinc finger RANBP2-type containing 1

Associated with

Degradation of beta-catenin by the destruction complex
(R-HSA-195253)
Deubiquitination
(R-HSA-5688426)
Metabolism of proteins
(R-HSA-392499)
Ovarian tumor domain proteases
(R-HSA-5689896)
Post-translational protein modification
(R-HSA-597592)
Signaling by wnt
(R-HSA-195721)
Signal transduction
(R-HSA-162582)
Cell migration
(GO:0016477)
Cysteine-type deubiquitinase activity
(GO:0004843)
Cytoplasm
(GO:0005737)
Cytoskeleton organization
(GO:0007010)
Cytosol
(GO:0005829)
Deubiquitinase activity
(GO:0101005)
Intracellular membrane-bounded organelle
(GO:0043231)
K63-linked polyubiquitin modification-dependent protein binding
(GO:0070530)
Metal ion binding
(GO:0046872)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Polyubiquitin modification-dependent protein binding
(GO:0031593)
Positive regulation of wnt signaling pathway
(GO:0030177)
Protein binding
(GO:0005515)
Protein deubiquitination involved in ubiquitin-dependent protein catabolic process
(GO:0071947)
Protein k29-linked deubiquitination
(GO:0035523)
Protein k33-linked deubiquitination
(GO:1990168)
Protein k63-linked deubiquitination
(GO:0070536)
Regulation of cell morphogenesis
(GO:0022604)
Wnt signaling pathway
(GO:0016055)

Other Information

Proteins

ZRAN1_HUMAN

Genular Protein ID: 3399403040

Symbol: ZRAN1_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q9UGI0 B4DZ98 D3DRF4 Q5SQP6 Q69YK3

Database IDs:

Citations:

PubMed ID: 11463333

Title: Isolation and characterization of two novel A20-like proteins.

PubMed ID: 11463333

DOI: 10.1042/0264-6021:3570617

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15164054

Title: The DNA sequence and comparative analysis of human chromosome 10.

PubMed ID: 15164054

DOI: 10.1038/nature02462

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 18281465

Title: Trabid, a new positive regulator of Wnt-induced transcription with preference for binding and cleaving K63-linked ubiquitin chains.

PubMed ID: 18281465

DOI: 10.1101/gad.463208

PubMed ID: 21834987

Title: Identification and characterization of a set of conserved and new regulators of cytoskeletal organisation, cell morphology and migration.

PubMed ID: 21834987

DOI: 10.1186/1741-7007-9-54

PubMed ID: 23827681

Title: OTU deubiquitinases reveal mechanisms of linkage specificity and enable ubiquitin chain restriction analysis.

PubMed ID: 23827681

DOI: 10.1016/j.cell.2013.05.046

PubMed ID: 25752573

Title: K29-selective ubiquitin binding domain reveals structural basis of specificity and heterotypic nature of K29 polyubiquitin.

PubMed ID: 25752573

DOI: 10.1016/j.molcel.2015.01.041

PubMed ID: 33637724

Title: VPS34 K29/K48 branched ubiquitination governed by UBE3C and TRABID regulates autophagy, proteostasis and liver metabolism.

PubMed ID: 33637724

DOI: 10.1038/s41467-021-21715-1

PubMed ID: 22157957

Title: An ankyrin-repeat ubiquitin-binding domain determines TRABID's specificity for atypical ubiquitin chains.

PubMed ID: 22157957

DOI: 10.1038/nsmb.2169

PubMed ID: 25752577

Title: Assembly and specific recognition of K29- and K33-linked polyubiquitin.

PubMed ID: 25752577

DOI: 10.1016/j.molcel.2015.01.042

Sequence Information:

Length: 708
Mass: 80967
Checksum: DBB831697F450248
Sequence:

MSERGIKWAC EYCTYENWPS AIKCTMCRAQ RPSGTIITED PFKSGSSDVG RDWDPSSTEG 
GSSPLICPDS SARPRVKSSY SMENANKWSC HMCTYLNWPR AIRCTQCLSQ RRTRSPTESP 
QSSGSGSRPV AFSVDPCEEY NDRNKLNTRT QHWTCSVCTY ENWAKAKRCV VCDHPRPNNI 
EAIELAETEE ASSIINEQDR ARWRGSCSSG NSQRRSPPAT KRDSEVKMDF QRIELAGAVG 
SKEELEVDFK KLKQIKNRMK KTDWLFLNAC VGVVEGDLAA IEAYKSSGGD IARQLTADEV 
RLLNRPSAFD VGYTLVHLAI RFQRQDMLAI LLTEVSQQAA KCIPAMVCPE LTEQIRREIA 
ASLHQRKGDF ACYFLTDLVT FTLPADIEDL PPTVQEKLFD EVLDRDVQKE LEEESPIINW 
SLELATRLDS RLYALWNRTA GDCLLDSVLQ ATWGIYDKDS VLRKALHDSL HDCSHWFYTR 
WKDWESWYSQ SFGLHFSLRE EQWQEDWAFI LSLASQPGAS LEQTHIFVLA HILRRPIIVY 
GVKYYKSFRG ETLGYTRFQG VYLPLLWEQS FCWKSPIALG YTRGHFSALV AMENDGYGNR 
GAGANLNTDD DVTITFLPLV DSERKLLHVH FLSAQELGNE EQQEKLLREW LDCCVTEGGV 
LVAMQKSSRR RNHPLVTQMV EKWLDRYRQI RPCTSLSDGE EDEDDEDE

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: ZRANB1

Associated with

Other Information

Isolation and characterization of two novel A20-like proteins. PubMed ID: 11463333

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

The DNA sequence and comparative analysis of human chromosome 10. PubMed ID: 15164054

The full-ORF clone resource of the German cDNA consortium. PubMed ID: 17974005

Trabid, a new positive regulator of Wnt-induced transcription with preference for binding and cleaving K63-linked ubiquitin chains. PubMed ID: 18281465

Identification and characterization of a set of conserved and new regulators of cytoskeletal organisation, cell morphology and migration. PubMed ID: 21834987

OTU deubiquitinases reveal mechanisms of linkage specificity and enable ubiquitin chain restriction analysis. PubMed ID: 23827681

K29-selective ubiquitin binding domain reveals structural basis of specificity and heterotypic nature of K29 polyubiquitin. PubMed ID: 25752573

VPS34 K29/K48 branched ubiquitination governed by UBE3C and TRABID regulates autophagy, proteostasis and liver metabolism. PubMed ID: 33637724

An ankyrin-repeat ubiquitin-binding domain determines TRABID's specificity for atypical ubiquitin chains. PubMed ID: 22157957

Assembly and specific recognition of K29- and K33-linked polyubiquitin. PubMed ID: 25752577