Details for: DPP8
Associated with
Other Information
Genular Protein ID: 1967713657
Symbol: DPP8_HUMAN
Name: Dipeptidyl peptidase IV-related protein 1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11012666
Title: Cloning, expression and chromosomal localization of a novel human dipeptidyl peptidase (DPP) IV homolog, DPP8.
PubMed ID: 11012666
PubMed ID: 12662155
Title: Cloning and characterization of dipeptidyl peptidase 10, a new member of an emerging subgroup of serine proteases.
PubMed ID: 12662155
DOI: 10.1042/bj20021914
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 12534281
Title: Structural requirements for catalysis, expression, and dimerization in the CD26/DPIV gene family.
PubMed ID: 12534281
DOI: 10.1021/bi026846s
PubMed ID: 15039077
Title: Purification and characterization of human prolyl dipeptidase DPP8 in Sf9 insect cells.
PubMed ID: 15039077
PubMed ID: 15664838
Title: Novel isoindoline compounds for potent and selective inhibition of prolyl dipeptidase DPP8.
PubMed ID: 15664838
PubMed ID: 20536396
Title: Hydrophilic residues surrounding the S1 and S2 pockets contribute to dimerisation and catalysis in human dipeptidyl peptidase 8 (DP8).
PubMed ID: 20536396
DOI: 10.1515/bc.2010.111
PubMed ID: 27820798
Title: DPP8 and DPP9 inhibition induces pro-caspase-1-dependent monocyte and macrophage pyroptosis.
PubMed ID: 27820798
PubMed ID: 29967349
Title: DPP8/DPP9 inhibitor-induced pyroptosis for treatment of acute myeloid leukemia.
PubMed ID: 29967349
PubMed ID: 32796818
Title: DPP8/9 inhibitors activate the CARD8 inflammasome in resting lymphocytes.
PubMed ID: 32796818
PubMed ID: 34019797
Title: Dipeptidyl peptidase 9 sets a threshold for CARD8 inflammasome formation by sequestering its active C-terminal fragment.
PubMed ID: 34019797
PubMed ID: 33731929
Title: Structural and biochemical mechanisms of NLRP1 inhibition by DPP9.
PubMed ID: 33731929
PubMed ID: 33731932
Title: DPP9 sequesters the C terminus of NLRP1 to repress inflammasome activation.
PubMed ID: 33731932
PubMed ID: 29382749
Title: Structures and mechanism of dipeptidyl peptidases 8 and 9, important players in cellular homeostasis and cancer.
PubMed ID: 29382749
Sequence Information:
- Length: 898
- Mass: 103358
- Checksum: 60B0D036F026DE2A
- Sequence:
MWKRSEQMKI KSGKCNMAAA METEQLGVEI FETADCEENI ESQDRPKLEP FYVERYSWSQ LKKLLADTRK YHGYMMAKAP HDFMFVKRND PDGPHSDRIY YLAMSGENRE NTLFYSEIPK TINRAAVLML SWKPLLDLFQ ATLDYGMYSR EEELLRERKR IGTVGIASYD YHQGSGTFLF QAGSGIYHVK DGGPQGFTQQ PLRPNLVETS CPNIRMDPKL CPADPDWIAF IHSNDIWISN IVTREERRLT YVHNELANME EDARSAGVAT FVLQEEFDRY SGYWWCPKAE TTPSGGKILR ILYEENDESE VEIIHVTSPM LETRRADSFR YPKTGTANPK VTFKMSEIMI DAEGRIIDVI DKELIQPFEI LFEGVEYIAR AGWTPEGKYA WSILLDRSQT RLQIVLISPE LFIPVEDDVM ERQRLIESVP DSVTPLIIYE ETTDIWINIH DIFHVFPQSH EEEIEFIFAS ECKTGFRHLY KITSILKESK YKRSSGGLPA PSDFKCPIKE EIAITSGEWE VLGRHGSNIQ VDEVRRLVYF EGTKDSPLEH HLYVVSYVNP GEVTRLTDRG YSHSCCISQH CDFFISKYSN QKNPHCVSLY KLSSPEDDPT CKTKEFWATI LDSAGPLPDY TPPEIFSFES TTGFTLYGML YKPHDLQPGK KYPTVLFIYG GPQVQLVNNR FKGVKYFRLN TLASLGYVVV VIDNRGSCHR GLKFEGAFKY KMGQIEIDDQ VEGLQYLASR YDFIDLDRVG IHGWSYGGYL SLMALMQRSD IFRVAIAGAP VTLWIFYDTG YTERYMGHPD QNEQGYYLGS VAMQAEKFPS EPNRLLLLHG FLDENVHFAH TSILLSFLVR AGKPYDLQIY PQERHSIRVP ESGEHYELHL LHYLQENLGS RIAALKVI
Genular Protein ID: 3417611847
Symbol: A8K4U2_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 898
- Mass: 103214
- Checksum: 370B53B824B1007A
- Sequence:
MWKRSEQMKI KSGKCNMAAA METEQLGVEI FETADCEENI ESQDRPKLEP FYVERYSWSQ LKKLLADTRK YHGYMMAKAP HDFMFVKRND PDGPHSDRIY YLAMSGENRE NTLFYSEIPK TINRAAVLML SWKPLLDLFQ ATLDYGMYSR EEELLRERKR IGTVGIASYD YHQGSGTFLF QAGSGIYHVK DGGPQGFTQQ PLRPNLVETS CPNIRMDPKL CPADPDWIAF IHSNDIWISN IVTREERRLT YVHNELANME EDARSAGVAT FVLQEEFDRY SGYWWCPKAE TTPSGGKILR ILYEENDESE VEIIHVTSPM LETRRADSFR YPKTGTANPK VTFKMSEIMI DAEGRIIDVI DKELIQPFEI LFEGVEYIAR AGWTPEGKYA WSILLDRSQT RLQIVLISPE LFIPVEDDVM ERQRLIESVP DSVTPLIIYE ETTDIWINIH DIFHVFPQSH EEEIEFIFAS ECKTGFRHLY KITSILKESK YKRSSGGLPA PSDFKCPIKE EIAITSGEWE VLGRHGSNIQ VDEVRRLVYF EGTKDSPLEH HLYVVSYVNP GEVTRLTDRG YSHSCCISQH CDFFISKYSN QKNPHCVSLY KLSSPEDDPT CKTKEFWATI LDSAGPLPDY TPPEIFSFES TTGFTLYGML YKPHDLQPGK KYPTVLFIYG GPQVQLVNNR FKGVKYFRLN TLASLGYVVV VIDNRGSCHR GLKFEGAFKY KMGQIGIDDQ VEGLQYLASR YDFIDLDRVG IHGWSYGGYL SLMALMQRSD IFRVAIAGAP VTLWIFYDTG YTERYMGHPD QNEQGYYLGS VAMQAEKFPS EPNRLLLLHG FLDGNVHFAH TSILLSFLVR AGKPYDLQIY PQERHSIRVP ESGEHYELHL LHYLQENLGS RIAALKVI
Genular Protein ID: 1941390730
Symbol: B4DLA8_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 882
- Mass: 101416
- Checksum: CC9D95665872AA27
- Sequence:
MAAAMETEQL GVEIFETADC EENIESQDRP KLEPFYVERY SWSQLKKLLA DTRKYHGYMM AKAPHDFMFV KRNDPDGPHS DRIYYLAMSG ENRENTLFYS EIPKTINRAA VLMLSWKPLL DLFQATLDYG MYSREEELLR ERKRIGTVGI ASYDYHQGSG TFLFQAGSGI YHVKDGGPQG FTQQPLRPNL VETSCPNIRM DPKLCPADPD WIAFIHSNDI WISNIVTREE RRLTYVHNEL ANMEEDARSA GVATFVLQEE FDRYSGYWWC PKAETTPSGG KILRILYEEN DESEVEIIHV TSPMLETRRA DSFRYSKTGT ANPKVTFKMS EIMIDAEGRI IDVIDKELIQ PFEILFEGVE YIARAGWTPE GKYAWSILLD RSQTRLQIVL ISPELFIPVE DDVMERQRLI ESVPDSVTPL IIYEETTDIW INIHDIFHVF PQSHEEEIEF IFASECKTGF RHLYKITSIL KESKYKRSSG GLPAPSDFKC PIKEEIAITC GEWEVLGRHG SNIQVDEVRR LVYFEGTKDS PLEHHLYVVS YVNPGEVTRL TDRGYSHSCC ISQHCDFFIS KYSNQKNPHC VSLYKLSSPE DDPTCKTKEF WATILDSAGP LPDYTPPEIF SFESTTGFTL YGMLYKPHDL QPGKKYPTVL FIYGGPQVQL VNNRFKGVKY FRLNTLASLG YVVVVIDNRG SCHRGLKFEG AFKYKMGQIE IDDQVEGLQY LASRYDFTDL DRVGIHGWSY GGYLSLMALM QRSDIFRVAI AGAPVTLWIF YDTGYTERYM GHPDQNEQGY YLGSVAMQAE KFPSEPNRLL LLHGFLDENV HFAHTSILLS FLVRAGKPYD LQIYPQERHS IRVPESGEHY ELHLLHYLQE NLGSRIAALK VI
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.