Details for: RNF43

Gene ID: 54894

Symbol: RNF43

Ensembl ID: ENSG00000108375

Description: ring finger protein 43

Associated with

Other Information

Genular Protein ID: 1768733943

Symbol: RNF43_HUMAN

Name: E3 ubiquitin-protein ligase RNF43

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 15492824

Title: A novel oncoprotein RNF43 functions in an autocrine manner in colorectal cancer.

PubMed ID: 15492824

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15623641

Title: Ring finger protein 43 as a new target for cancer immunotherapy.

PubMed ID: 15623641

DOI: 10.1158/1078-0432.ccr-04-0104

PubMed ID: 18313049

Title: A cancer-associated RING finger protein, RNF43, is a ubiquitin ligase that interacts with a nuclear protein, HAP95.

PubMed ID: 18313049

DOI: 10.1016/j.yexcr.2008.01.013

PubMed ID: 18655028

Title: Proteomic identification of a PSF/p54nrb heterodimer as RNF43 oncoprotein-interacting proteins.

PubMed ID: 18655028

DOI: 10.1002/pmic.200800083

PubMed ID: 22575959

Title: ZNRF3 promotes Wnt receptor turnover in an R-spondin-sensitive manner.

PubMed ID: 22575959

DOI: 10.1038/nature11019

PubMed ID: 22895187

Title: Tumour suppressor RNF43 is a stem-cell E3 ligase that induces endocytosis of Wnt receptors.

PubMed ID: 22895187

DOI: 10.1038/nature11308

PubMed ID: 24512911

Title: Germline mutations in oncogene-induced senescence pathways are associated with multiple sessile serrated adenomas.

PubMed ID: 24512911

DOI: 10.1053/j.gastro.2013.10.045

PubMed ID: 27081527

Title: A deleterious RNF43 germline mutation in a severely affected serrated polyposis kindred.

PubMed ID: 27081527

DOI: 10.1038/hgv.2015.13

PubMed ID: 29769720

Title: RSPO2 inhibition of RNF43 and ZNRF3 governs limb development independently of LGR4/5/6.

PubMed ID: 29769720

DOI: 10.1038/s41586-018-0118-y

PubMed ID: 23756651

Title: The structural basis of R-spondin recognition by LGR5 and RNF43.

PubMed ID: 23756651

DOI: 10.1101/gad.219915.113

Sequence Information:

  • Length: 783
  • Mass: 85722
  • Checksum: 4E87EA0CC359C858
  • Sequence:
  • MSGGHQLQLA ALWPWLLMAT LQAGFGRTGL VLAAAVESER SAEQKAIIRV IPLKMDPTGK 
    LNLTLEGVFA GVAEITPAEG KLMQSHPLYL CNASDDDNLE PGFISIVKLE SPRRAPRPCL 
    SLASKARMAG ERGASAVLFD ITEDRAAAEQ LQQPLGLTWP VVLIWGNDAE KLMEFVYKNQ 
    KAHVRIELKE PPAWPDYDVW ILMTVVGTIF VIILASVLRI RCRPRHSRPD PLQQRTAWAI 
    SQLATRRYQA SCRQARGEWP DSGSSCSSAP VCAICLEEFS EGQELRVISC LHEFHRNCVD 
    PWLHQHRTCP LCMFNITEGD SFSQSLGPSR SYQEPGRRLH LIRQHPGHAH YHLPAAYLLG 
    PSRSAVARPP RPGPFLPSQE PGMGPRHHRF PRAAHPRAPG EQQRLAGAQH PYAQGWGLSH 
    LQSTSQHPAA CPVPLRRARP PDSSGSGESY CTERSGYLAD GPASDSSSGP CHGSSSDSVV 
    NCTDISLQGV HGSSSTFCSS LSSDFDPLVY CSPKGDPQRV DMQPSVTSRP RSLDSVVPTG 
    ETQVSSHVHY HRHRHHHYKK RFQWHGRKPG PETGVPQSRP PIPRTQPQPE PPSPDQQVTR 
    SNSAAPSGRL SNPQCPRALP EPAPGPVDAS SICPSTSSLF NLQKSSLSAR HPQRKRRGGP 
    SEPTPGSRPQ DATVHPACQI FPHYTPSVAY PWSPEAHPLI CGPPGLDKRL LPETPGPCYS 
    NSQPVWLCLT PRQPLEPHPP GEGPSEWSSD TAEGRPCPYP HCQVLSAQPG SEEELEELCE 
    QAV

Genular Protein ID: 3823999562

Symbol: J3KSE3_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 16625196

Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.

PubMed ID: 16625196

DOI: 10.1038/nature04689

Sequence Information:

  • Length: 742
  • Mass: 81423
  • Checksum: F628E2FAB786B45F
  • Sequence:
  • MAGERGASAV LFDITEDRAA AEQLQQPLGL TWPVVLIWGN DAEKLMEFVY KNQKAHVRIE 
    LKEPPAWPDY DVWILMTVVG TIFVIILASV LRIRCRPRHS RPDPLQQRTA WAISQLATRR 
    YQASCRQARG EWPDSGSSCS SAPVCAICLE EFSEGQELRV ISCLHEFHRN CVDPWLHQHR 
    TCPLCMFNIT EGDSFSQSLG PSRSYQEPGR RLHLIRQHPG HAHYHLPAAY LLGPSRSAVA 
    RPPRPGPFLP SQEPGMGPRH HRFPRAAHPR APGEQQRLAG AQHPYAQGWG LSHLQSTSQH 
    PAACPVPLRR ARPPDSSGSG ESYCTERSGY LADGPASDSS SGPCHGSSSD SVVNCTDISL 
    QGVHGSSSTF CSSLSSDFDP LVYCSPKGDP QRVDMQPSVT SRPRSLDSVV PTGETQVSSH 
    VHYHRHRHHH YKKRFQWHGR KPGPETGVPQ SRPPIPRTQP QPEPPSPDQQ VTRSNSAAPS 
    GRLSNPQCPR ALPEPAPGPV DASSICPSTS SLFNLQKSSL SARHPQRKRR GGPSEPTPGS 
    RPQDATVHPA CQIFPHYTPS VAYPWSPEAH PLICGPPGLD KRLLPETPGP CYSNSQPVWL 
    CLTPRQPLEP HPPGEGPSEW SSDTAEGRPC PYPHCQVLSA QPGEFSEGSG CGRERRLQLN 
    ISGQVKSANK GLMEAEKDTA EMTTKILNHR DSVSCWLECR NTPPLPGATP LVGRSQGGPR 
    EVLVWLRHQK GTWKAGCDGS CL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.