Details for: CASZ1

Gene ID: 54897

Symbol: CASZ1

Ensembl ID: ENSG00000130940

Description: castor zinc finger 1

Associated with

  • Chromatin
    (GO:0000785)
  • Cytosol
    (GO:0005829)
  • Dna-binding transcription activator activity, rna polymerase ii-specific
    (GO:0001228)
  • Dna-binding transcription factor activity, rna polymerase ii-specific
    (GO:0000981)
  • Intracellular membrane-bounded organelle
    (GO:0043231)
  • Metal ion binding
    (GO:0046872)
  • Nucleoplasm
    (GO:0005654)
  • Nucleus
    (GO:0005634)
  • Positive regulation of dna-templated transcription
    (GO:0045893)
  • Positive regulation of transcription by rna polymerase ii
    (GO:0045944)
  • Regulation of neuron differentiation
    (GO:0045664)
  • Rna polymerase ii transcription regulatory region sequence-specific dna binding
    (GO:0000977)

Other Information

Genular Protein ID: 380019133

Symbol: CASZ1_HUMAN

Name: Zinc finger protein castor homolog 1

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 16322216

Title: Identification and characterization of survival-related gene, a novel cell survival gene controlling apoptosis and tumorigenesis.

PubMed ID: 16322216

DOI: 10.1158/0008-5472.can-05-2176

PubMed ID: 16631614

Title: Molecular cloning and characterization of human Castor, a novel human gene upregulated during cell differentiation.

PubMed ID: 16631614

DOI: 10.1016/j.bbrc.2006.03.207

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 23639441

Title: CASZ1 promotes vascular assembly and morphogenesis through the direct regulation of an EGFL7/RhoA-mediated pathway.

PubMed ID: 23639441

DOI: 10.1016/j.devcel.2013.03.003

PubMed ID: 27693370

Title: CASZ1 loss-of-function mutation associated with congenital heart disease.

PubMed ID: 27693370

DOI: 10.1016/j.gene.2016.09.044

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

Sequence Information:

  • Length: 1759
  • Mass: 190069
  • Checksum: 4F5146BE72606654
  • Sequence:
  • MDLGTAEGTR CTDPPAGKPA MAPKRKGGLK LNAICAKLSR QVVVEKRADA GSHTEGSPSQ 
    PRDQERSGPE SGAARAPRSE EDKRRAVIEK WVNGEYSEEP APTPVLGRIA REGLELPPEG 
    VYMVQPQGCS DEEDHAEEPS KDGGALEEKD SDGAASKEDS GPSTRQASGE ASSLRDYAAS 
    TMTEFLGMFG YDDQNTRDEL ARKISFEKLH AGSTPEAATS SMLPTSEDTL SKRARFSKYE 
    EYIRKLKAGE QLSWPAPSTK TEERVGKEVV GTLPGLRLPS STAHLETKAT ILPLPSHSSV 
    QMQNLVARAS KYDFFIQKLK TGENLRPQNG STYKKPSKYD LENVKYLHLF KPGEGSPDMG 
    GAIAFKTGKV GRPSKYDVRG IQKPGPAKVP PTPSLAPAPL ASVPSAPSAP GPGPEPPASL 
    SFNTPEYLKS TFSKTDSITT GTVSTVKNGL PTDKPAVTED VNIYQKYIAR FSGSQHCGHI 
    HCAYQYREHY HCLDPECNYQ RFTSKQDVIR HYNMHKKRDN SLQHGFMRFS PLDDCSVYYH 
    GCHLNGKSTH YHCMQVGCNK VYTSTSDVMT HENFHKKNTQ LINDGFQRFR ATEDCGTADC 
    QFYGQKTTHF HCRRPGCTFT FKNKCDIEKH KSYHIKDDAY AKDGFKKFYK YEECKYEGCV 
    YSKATNHFHC IRAGCGFTFT STSQMTSHKR KHERRHIRSS GALGLPPSLL GAKDTEHEES 
    SNDDLVDFSA LSSKNSSLSA SPTSQQSSAS LAAATAATEA GPSATKPPNS KISGLLPQGL 
    PGSIPLALAL SNSGLPTPTP YFPILAGRGS TSLPVGTPSL LGAVSSGSAA SATPDTPTLV 
    ASGAGDSAPV AAASVPAPPA SIMERISASK GLISPMMARL AAAALKPSAT FDPGSGQQVT 
    PARFPPAQVK PEPGESTGAP GPHEASQDRS LDLTVKEPSN ESNGHAVPAN SSLLSSLMNK 
    MSQGNPGLGS LLNIKAEAEG SPAAEPSPFL GKAVKALVQE KLAEPWKVYL RRFGTKDFCD 
    GQCDFLHKAH FHCVVEECGA LFSTLDGAIK HANFHFRTEG GAAKGNTEAA FPASAAETKP 
    PMAPSSPPVP PVTTATVSSL EGPAPSPASV PSTPTLLAWK QLASTIPQMP QIPASVPHLP 
    ASPLATTSLE NAKPQVKPGF LQFQENDPCL ATDCKYANKF HFHCLFGNCK YVCKTSGKAE 
    SHCLDHINPN NNLVNVRDQF AYYSLQCLCP NQHCEFRMRG HYHCLRTGCY FVTNITTKLP 
    WHIKKHEKAE RRAANGFKYF TKREECGRLG CKYNQVNSHF HCIREGCQFS FLLKHQMTSH 
    ARKHMRRMLG KNFDRVPPSQ GPPGLMDAET DECMDYTGCS PGAMSSESST MDRSCSSTPV 
    GNESTAAGNT ISMPTASGAK KRFWIIEDMS PFGKRRKTAS SRKMLDEGMM LEGFRRFDLY 
    EDCKDAACQF SLKVTHYHCT RENCGYKFCG RTHMYKHAQH HDRVDNLVLD DFKRFKASLS 
    CHFADCPFSG TSTHFHCLRC RFRCTDSTKV TAHRKHHGKQ DVISAAGFCQ FSSSADCAVP 
    DCKYKLKCSH FHCTFPGCRH TVVGMSQMDS HKRKHEKQER GEPAAEGPAP GPPISLDGSL 
    SLGAEPGSLL FLQSAAAGLG LALGDAGDPG PPDAAAPGPR EGAAAAAAAA GESSQEDEEE 
    ELELPEEEAE DDEDEDDDED DDDEDDDEDD DDEDLRTDSE ESLPEAAAEA AGAGARTPAL 
    AALAALGAPG PAPTAASSP

Genular Protein ID: 609628638

Symbol: B3KRV8_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

Sequence Information:

  • Length: 1166
  • Mass: 124816
  • Checksum: 530176F28E97F212
  • Sequence:
  • MDLGTAEGTR CTDPPAGKPA MAPKRKGGLK LNAICAKLSR QVVVEKRADA GSHTEGSPSQ 
    PRDQERSGPE SGAARAPRSE EDKRRAVIEK WVNGEYSEEP APTPVLGRIA REGLELPPEG 
    VYMVQPQGCS DEEDHAEEPS KDGGALEEKD SDGAASKEDS GPSTRQASGE ASSLRDYAAS 
    TMTEFLGMFG YDDQNTRDEL ARKISFEKLH AGSTPEAATS SMLPTSEDTL SKRARFSKYE 
    EYIRKLKAGE QLSWPAPSTK TEERVGKEVV GTLPGLRLPS STAHLETKAT ILPLPSHSSV 
    QMQNLVARAS KYDFFIQKLK TGENLRPQNG STYKKPSKYD LENVKYLHLF KPGEGSPDMG 
    GAIAFKTGKV GRPSKYDVRG IQKPGPAKVP PTPSLAPAPL ASVPSAPSAP GPGPEPPASL 
    SFNTPEYLKS TFSKTDSITT GTVSTVKNGL PTDKPAVTED VNIYQKYIAR FSGSQHCGHI 
    HCAYQYREHY HCLDPECNYR RFTSKQDVIR HYNMHKKRDN SLQHGFMRFS PLDDCSVYYH 
    GCHLNGKSTH YHCMQVGCNK VYTSTSDVMT HENFHKKNTQ LINDGFQRFR ATEDCGTADC 
    QFYGQKTTHF HCRRPGCTFT FKNKCDIEKH KSYHIKDDAY AKDGFKKFYK YEECKYEGCV 
    YSKATNHFHC IRAGCGFTFT STSQMTSHKR KHERRHIRSS GALGLPPSLL GAKDTEHEES 
    SNDDLVDFSA LSSKNSSLSA SPTSQQSSAS LAAATAATEA GPSATKPPNS KISGLLPQGL 
    PGSIPLALAL SNSGLPTPTP YFPILAGRGS TSLPVGTPSL LGAVSSGSAA SATPDTPTLV 
    ASGAGDSAPV AAASVPAPPA SIMERISASK GLISPMMARL AAAALKPSAT FDPGSGQQVT 
    PARFPPAQVK PEPGESTGAP GPHEASQDRS LDLTVKEPSN ESNGHAVPAN SSLLSSLMNK 
    MSQGNPGLGS LLNIKAEAEG SPAAEPSPFL GKAVKALVQE KLAEPWKVYL RRFGTKDFCD 
    GQCDFLHKAH FHCVVEECGA LFSTLDGAIK HANFHFRTEG GAAKGNTEAA FPASAAETKP 
    PMAPSSPPVP PVTTATVSSL EGPAPSPASV PSTPTLLAWK QLASTIPQMP QIPASVPHLP 
    ASPLATTSLE NAKPQVKPGF LQFQEK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.