Details for: AUH

Gene ID: 549

Symbol: AUH

Ensembl ID: ENSG00000148090

Description: AU RNA binding methylglutaconyl-CoA hydratase

Associated with

Other Information

Genular Protein ID: 3145388715

Symbol: AUHM_HUMAN

Name: AU-specific RNA-binding enoyl-CoA hydratase

UniProtKB Accession Codes:

Q13825 B1ALV7 B1ALV8 Q8WUE4

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BioCyc 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 1 CTD 1 ChEBI 12 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EC 2 EMBL 7 EPD 1 Ensembl 2 EvolutionaryTrace 1 GO 8 Gene3D 1 GeneCards 1 GeneTree 1 Genevisible 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 3 MalaCards 1 MassIVE 1 MaxQB 1 MoonProt 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 4 PDBsum 3 PIR 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 1 RefSeq 2 Rhea 8 SABIO-RK 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TopDownProteomics 2 TreeFam 1 UCSC 1 UniPathway 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 7892223

Title: AUH, a gene encoding an AU-specific RNA binding protein with intrinsic enoyl-CoA hydratase activity.

PubMed ID: 7892223

DOI: 10.1073/pnas.92.6.2051

PubMed ID: 15164053

Title: DNA sequence and analysis of human chromosome 9.

PubMed ID: 15164053

DOI: 10.1038/nature02465

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12434311

Title: 3-methylglutaconic aciduria type I is caused by mutations in AUH.

PubMed ID: 12434311

DOI: 10.1086/344712

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 16640564

Title: Biochemical characterization of human 3-methylglutaconyl-CoA hydratase and its role in leucine metabolism.

PubMed ID: 16640564

DOI: 10.1111/j.1742-4658.2006.05218.x

PubMed ID: 29056341

Title: The human knockout gene CLYBL connects itaconate to vitamin B12.

PubMed ID: 29056341

DOI: 10.1016/j.cell.2017.09.051

PubMed ID: 11738050

Title: Crystal structure of human AUH protein, a single-stranded RNA binding homolog of enoyl-CoA hydratase.

PubMed ID: 11738050

DOI: 10.1016/s0969-2126(01)00686-4

PubMed ID: 12655555

Title: Mutations in the AUH gene cause 3-methylglutaconic aciduria type I.

PubMed ID: 12655555

DOI: 10.1002/humu.10202

Sequence Information:

  • Length: 339
  • Mass: 35609
  • Checksum: E04FEB95933FB30B
  • Sequence:
    • MAAAVAAAPG ALGSLHAGGA RLVAACSAWL CPGLRLPGSL AGRRAGPAIW AQGWVPAAGG 
PAPKRGYSSE MKTEDELRVR HLEEENRGIV VLGINRAYGK NSLSKNLIKM LSKAVDALKS 
DKKVRTIIIR SEVPGIFCAG ADLKERAKMS SSEVGPFVSK IRAVINDIAN LPVPTIAAID 
GLALGGGLEL ALACDIRVAA SSAKMGLVET KLAIIPGGGG TQRLPRAIGM SLAKELIFSA 
RVLDGKEAKA VGLISHVLEQ NQEGDAAYRK ALDLAREFLP QGPVAMRVAK LAINQGMEVD 
LVTGLAIEEA CYAQTIPTKD RLEGLLAFKE KRPPRYKGE

Genular Protein ID: 3725633119

Symbol: B4DYI6_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4DYI6

Database IDs:

ARBA 2 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 EMBL 2 GO 1 GenomeRNAi 1 IntAct 1 InterPro 3 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 1 PeptideAtlas 1 Pfam 1 ProteomicsDB 1 RefSeq 1 RuleBase 1 SMR 1 SUPFAM 1

Sequence Information:

  • Length: 255
  • Mass: 26335
  • Checksum: 07D5F5EDE1273C7A
  • Sequence:
    • MAAAVAAAPG ALGSLHAGGA RLVAACSAWL CPGLRLPGSL AGRRAGPAIW AQGWVPAAGG 
PAPKRGYSSE MKTEDELRVR HLEEENRGIV VLGINRAYGK NSLSKNLIKM LSKAVDALKS 
DKKVRTIIIR SEVPGIFCAG ADLKERAKMS SSEVGPFVSK IRAVINDIAN LPVPTIAAID 
GLALGGGLEL ALACDIRVAA SSAKMGLVET KLAIIPGGVT SSTEVLNPSK SSMKIGIIIF 
QTPVNIDILA SSHES

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.