Details for: DUS2

Gene ID: 54920

Symbol: DUS2

Ensembl ID: ENSG00000167264

Description: dihydrouridine synthase 2

Associated with

Other Information

Genular Protein ID: 2099005918

Symbol: DUS2L_HUMAN

Name: tRNA-dihydrouridine(20) synthase [NAD(P)+]-like

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 15994936

Title: A novel human tRNA-dihydrouridine synthase involved in pulmonary carcinogenesis.

PubMed ID: 15994936

DOI: 10.1158/0008-5472.can-05-0600

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15616553

Title: The sequence and analysis of duplication-rich human chromosome 16.

PubMed ID: 15616553

DOI: 10.1038/nature03187

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 18096616

Title: Interaction of human tRNA-dihydrouridine synthase-2 with interferon-induced protein kinase PKR.

PubMed ID: 18096616

DOI: 10.1093/nar/gkm1129

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 34798057

Title: Transcription-wide mapping of dihydrouridine reveals that mRNA dihydrouridylation is required for meiotic chromosome segregation.

PubMed ID: 34798057

DOI: 10.1016/j.molcel.2021.11.003

PubMed ID: 26143927

Title: From bacterial to human dihydrouridine synthase: automated structure determination.

PubMed ID: 26143927

DOI: 10.1107/s1399004715009220

PubMed ID: 26429968

Title: An extended dsRBD is required for post-transcriptional modification in human tRNAs.

PubMed ID: 26429968

DOI: 10.1093/nar/gkv989

PubMed ID: 30149704

Title: Electrostatic Potential in the tRNA Binding Evolution of Dihydrouridine Synthases.

PubMed ID: 30149704

DOI: 10.1021/acs.biochem.8b00584

PubMed ID: 30605527

Title: Molecular basis for transfer RNA recognition by the double-stranded RNA-binding domain of human dihydrouridine synthase 2.

PubMed ID: 30605527

DOI: 10.1093/nar/gky1302

Sequence Information:

  • Length: 493
  • Mass: 55050
  • Checksum: 8CFE5046CCF79DCD
  • Sequence:
  • MILNSLSLCY HNKLILAPMV RVGTLPMRLL ALDYGADIVY CEELIDLKMI QCKRVVNEVL 
    STVDFVAPDD RVVFRTCERE QNRVVFQMGT SDAERALAVA RLVENDVAGI DVNMGCPKQY 
    STKGGMGAAL LSDPDKIEKI LSTLVKGTRR PVTCKIRILP SLEDTLSLVK RIERTGIAAI 
    AVHGRKREER PQHPVSCEVI KAIADTLSIP VIANGGSHDH IQQYSDIEDF RQATAASSVM 
    VARAAMWNPS IFLKEGLRPL EEVMQKYIRY AVQYDNHYTN TKYCLCQMLR EQLESPQGRL 
    LHAAQSSREI CEAFGLGAFY EETTQELDAQ QARLSAKTSE QTGEPAEDTS GVIKMAVKFD 
    RRAYPAQITP KMCLLEWCRR EKLAQPVYET VQRPLDRLFS SIVTVAEQKY QSTLWDKSKK 
    LAEQAAAIVC LRSQGLPEGR LGEESPSLHK RKREAPDQDP GGPRAQELAQ PGDLCKKPFV 
    ALGSGEESPL EGW

Genular Protein ID: 628329166

Symbol: B4DKP8_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 458
  • Mass: 51378
  • Checksum: DE7BC5E177559AB9
  • Sequence:
  • MILNSLSLCY HNKLILAPMV RVGTLPMRLL ALDYGADIVY CEELIDLKMI QCKRVVNEVL 
    STVDFVAPDD RVVFRTCERE QNRVVFQMGG MGAALLSDSD KIEKILSTLV KGTRRPVTCK 
    IRILPSLEDT LSLVKRIERT GIAAIAVHGR KREERPQHPV SCEVIKAIAD TLSIPVIANG 
    GSHDHIQQYS DIEDFRQATA ASSVMVARAA MWNPSIFLKE GLRPLEEVMQ KYIRYAVQYD 
    NHYTNTKYCL CQMLREQLES PQGRLLHAAQ SSREICEAFG LGAFYEETTQ ELDAQQARLS 
    AKTSEQTGEP AEDTSGVIKM AVKFDRRAYP AQITPKMCLL EWCRREKLAQ PVYETVQRPL 
    DRLFSSIVTV AEQKYQSTLW DKSKKLAEQA AAIVCLRSQG LPEGRLGEES PSLHKRKREA 
    PDQDPGGPRA QELAQPGDLC KKPFVALGSG EESPLEGW

Genular Protein ID: 1387144457

Symbol: E7EUN9_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 15616553

Title: The sequence and analysis of duplication-rich human chromosome 16.

PubMed ID: 15616553

DOI: 10.1038/nature03187

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

Sequence Information:

  • Length: 458
  • Mass: 51388
  • Checksum: F89E12BCF2BC8D18
  • Sequence:
  • MILNSLSLCY HNKLILAPMV RVGTLPMRLL ALDYGADIVY CEELIDLKMI QCKRVVNEVL 
    STVDFVAPDD RVVFRTCERE QNRVVFQMGG MGAALLSDPD KIEKILSTLV KGTRRPVTCK 
    IRILPSLEDT LSLVKRIERT GIAAIAVHGR KREERPQHPV SCEVIKAIAD TLSIPVIANG 
    GSHDHIQQYS DIEDFRQATA ASSVMVARAA MWNPSIFLKE GLRPLEEVMQ KYIRYAVQYD 
    NHYTNTKYCL CQMLREQLES PQGRLLHAAQ SSREICEAFG LGAFYEETTQ ELDAQQARLS 
    AKTSEQTGEP AEDTSGVIKM AVKFDRRAYP AQITPKMCLL EWCRREKLAQ PVYETVQRPL 
    DRLFSSIVTV AEQKYQSTLW DKSKKLAEQA AAIVCLRSQG LPEGRLGEES PSLHKRKREA 
    PDQDPGGPRA QELAQPGDLC KKPFVALGSG EESPLEGW

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.