Details for: LIME1

Gene ID: 54923

Symbol: LIME1

Ensembl ID: ENSG00000203896

Description: Lck interacting transmembrane adaptor 1

Associated with

  • Adaptive immune response
    (GO:0002250)
  • B cell receptor complex
    (GO:0019815)
  • B cell receptor signaling pathway
    (GO:0050853)
  • Extracellular space
    (GO:0005615)
  • Protein binding
    (GO:0005515)
  • Protein kinase binding
    (GO:0019901)
  • Regulation of canonical nf-kappab signal transduction
    (GO:0043122)
  • Regulation of non-canonical nf-kappab signal transduction
    (GO:1901222)
  • Regulation of phosphatidylinositol 3-kinase/protein kinase b signal transduction
    (GO:0051896)
  • Regulation of release of sequestered calcium ion into cytosol
    (GO:0051279)
  • Regulation of transcription by rna polymerase ii
    (GO:0006357)
  • T cell receptor signaling pathway
    (GO:0050852)

Other Information

Genular Protein ID: 4033076764

Symbol: LIME1_HUMAN

Name: Lck-interacting transmembrane adapter 1

UniProtKB Accession Codes:

Q9H400 E1P5K5 E1P5K6 Q5JWJ2 Q6XYB3 Q9NX69

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CPTC 1 CTD 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 10 EPD 1 Ensembl 1 ExpressionAtlas 1 GO 11 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 1 KEGG 1 MANE-Select 1 MIM 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 RNAct 1 RefSeq 3 SAM 1 STRING 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 14610046

Title: LIME: a new membrane raft-associated adaptor protein involved in CD4 and CD8 coreceptor signaling.

PubMed ID: 14610046

DOI: 10.1084/jem.20031484

PubMed ID: 14610044

Title: LIME, a novel transmembrane adaptor protein, associates with p56lck and mediates T cell activation.

PubMed ID: 14610044

DOI: 10.1084/jem.20030232

PubMed ID: 15498874

Title: Large-scale cDNA transfection screening for genes related to cancer development and progression.

PubMed ID: 15498874

DOI: 10.1073/pnas.0404089101

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 11780052

Title: The DNA sequence and comparative analysis of human chromosome 20.

PubMed ID: 11780052

DOI: 10.1038/414865a

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16160011

Title: Transmembrane adaptor molecules: a new category of lymphoid-cell markers.

PubMed ID: 16160011

DOI: 10.1182/blood-2005-06-2273

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 295
  • Mass: 31288
  • Checksum: D85ACE978F2DC99E
  • Sequence:
    • MGLPVSWAPP ALWVLGCCAL LLSLWALCTA CRRPEDAVAP RKRARRQRAR LQGSATAAEA 
SLLRRTHLCS LSKSDTRLHE LHRGPRSSRA LRPASMDLLR PHWLEVSRDI TGPQAAPSAF 
PHQELPRALP AAAATAGCAG LEATYSNVGL AALPGVSLAA SPVVAEYARV QKRKGTHRSP 
QEPQQGKTEV TPAAQVDVLY SRVCKPKRRD PGPTTDPLDP KGQGAILALA GDLAYQTLPL 
RALDVDSGPL ENVYESIREL GDPAGRSSTC GAGTPPASSC PSLGRGWRPL PASLP

Genular Protein ID: 1250221583

Symbol: A0A087WT39_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A087WT39

Database IDs:

AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 DNASU 1 EMBL 2 Ensembl 2 ExpressionAtlas 1 GO 2 GeneTree 1 GenomeRNAi 1 HGNC 1 InterPro 1 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 Pfam 1 Proteomes 2 RefSeq 2 SAM 2 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11780052

Title: The DNA sequence and comparative analysis of human chromosome 20.

PubMed ID: 11780052

DOI: 10.1038/414865a

Sequence Information:

  • Length: 176
  • Mass: 18098
  • Checksum: 8DCA6E544654A6F6
  • Sequence:
    • MGLPVSWAPP ALWVLGCCAL LLSLWALCTA CRRPEDAVAP RKRARRQRAR LQGSATAAEA 
QVGHQTARAA PGPAQQQGPA ACQHGSPAPT LAGGVQGHHR TAGSPLCLPT PGAAPGSAGS 
CSHRRVRWPR GHLFQRGAGG PSRGQPGGQP CGGRVCPRPE AQRDPSQSPR ATAGED

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.