Details for: TIPIN

Gene ID: 54962

Symbol: TIPIN

Ensembl ID: ENSG00000075131

Description: TIMELESS interacting protein

Associated with

Other Information

Genular Protein ID: 3231083047

Symbol: TIPIN_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16572171

Title: Analysis of the DNA sequence and duplication history of human chromosome 15.

PubMed ID: 16572171

DOI: 10.1038/nature04601

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12875843

Title: Tipin, a novel timeless-interacting protein, is developmentally co-expressed with timeless and disrupts its self-association.

PubMed ID: 12875843

DOI: 10.1016/s0022-2836(03)00633-8

PubMed ID: 17116885

Title: Tipin and Timeless form a mutually protective complex required for genotoxic stress resistance and checkpoint function.

PubMed ID: 17116885

DOI: 10.1073/pnas.0609251103

PubMed ID: 17102137

Title: Human Tim/Timeless-interacting protein, Tipin, is required for efficient progression of S phase and DNA replication checkpoint.

PubMed ID: 17102137

DOI: 10.1074/jbc.m605596200

PubMed ID: 17141802

Title: Mammalian TIMELESS and Tipin are evolutionarily conserved replication fork-associated factors.

PubMed ID: 17141802

DOI: 10.1016/j.jmb.2006.10.097

PubMed ID: 17296725

Title: The human Tim/Tipin complex coordinates an Intra-S checkpoint response to UV that slows replication fork displacement.

PubMed ID: 17296725

DOI: 10.1128/mcb.02190-06

PubMed ID: 17525332

Title: ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.

PubMed ID: 17525332

DOI: 10.1126/science.1140321

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 20139726

Title: The many facets of the Tim-Tipin protein families' roles in chromosome biology.

PubMed ID: 20139726

DOI: 10.4161/cc.9.4.10676

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 23359676

Title: Human Tim-Tipin complex affects the biochemical properties of the replicative DNA helicase and DNA polymerases.

PubMed ID: 23359676

DOI: 10.1073/pnas.1222494110

PubMed ID: 28334766

Title: Crystal structure of the N-terminal domain of human Timeless and its interaction with Tipin.

PubMed ID: 28334766

DOI: 10.1093/nar/gkx139

PubMed ID: 35585232

Title: Fast and efficient DNA replication with purified human proteins.

PubMed ID: 35585232

DOI: 10.1038/s41586-022-04759-1

PubMed ID: 34700328

Title: A conserved mechanism for regulating replisome disassembly in eukaryotes.

PubMed ID: 34700328

DOI: 10.1038/s41586-021-04145-3

PubMed ID: 34694004

Title: Structure of a human replisome shows the organisation and interactions of a DNA replication machine.

PubMed ID: 34694004

DOI: 10.15252/embj.2021108819

Sequence Information:

  • Length: 301
  • Mass: 34555
  • Checksum: B0C69117A636CE3A
  • Sequence:
  • MLEPQENGVI DLPDYEHVED ETFPPFPPPA SPERQDGEGT EPDEESGNGA PVRVPPKRTV 
    KRNIPKLDAQ RLISERGLPA LRHVFDKAKF KGKGHEAEDL KMLIRHMEHW AHRLFPKLQF 
    EDFIDRVEYL GSKKEVQTCL KRIRLDLPIL HEDFVSNNDE VAENNEHDVT STELDPFLTN 
    LSESEMFASE LSRSLTEEQQ QRIERNKQLA LERRQAKLLS NSQTLGNDML MNTPRAHTVE 
    EVNTDEDQKE ESNGLNEDIL DNPCNDAIAN TLNEEETLLD QSFKNVQQQL DATSRNITEA 
    R

Genular Protein ID: 2115816592

Symbol: B4DRF3_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 200
  • Mass: 23299
  • Checksum: 9A5ED020570EEDBE
  • Sequence:
  • MLIRHMEHWA HRLFPKLQFE DFIDRVEYLG SKKEVQTCLK RIRLDLPILH EDFVSNNDEV 
    AENNEHDVTS TELDPFLTNL SESEMFASEL SRSLTEEQQQ RIERNKQLAL ERRQAKLLSN 
    SQTLGNDMLM NTPRAHTVEE VNTDEDQKEE SNGLNEDILD NPCNDSIANT LNEEETLLDQ 
    SFKNVQQQLD ATSRNITEAR

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.